Patents by Inventor Richard Reinier Zwaal

Richard Reinier Zwaal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasminogen and plasmin variants
    Patent number: 9644196
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatalytic destruction of the protease activity of plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: May 9, 2017
    Assignee: ThromboGenics NV
    Inventor: Richard Reinier Zwaal
  • Variants of plasminogen and plasmin
    Patent number: 9226953
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity of plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: January 5, 2016
    Assignee: ThromboGenics NV
    Inventor: Richard Reinier Zwaal
  • Plasminogen and plasmin variants
    Patent number: 9121014
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: September 1, 2015
    Assignee: ThromboGenies NV
    Inventor: Richard Reinier Zwaal
  • PLASMINOGEN AND PLASMIN VARIANTS
    Publication number: 20140205588
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatalytic destruction of the protease activity of plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Application
    Filed: August 13, 2012
    Publication date: July 24, 2014
    Applicant: THROMBOGENICS NV
    Inventor: Richard Reinier Zwaal
  • PLASMINOGEN AND PLASMIN VARIANTS
    Publication number: 20130273028
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Application
    Filed: January 4, 2012
    Publication date: October 17, 2013
    Applicant: ThromboGenics NV
    Inventor: Richard Reinier Zwaal
  • VARIANTS OF PLASMINOGEN AND PLASMIN
    Publication number: 20120114630
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity of plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Application
    Filed: July 9, 2010
    Publication date: May 10, 2012
    Applicant: THROMBOGENICS NV
    Inventor: Richard Reinier Zwaal