Patents by Inventor Richard Rest

Richard Rest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METAL OR METAL OXIDE DEPOSITED FIBROUS MATERIALS
    Publication number: 20110192789
    Abstract: A method for electrospraying nanosized metal or metal oxide particles onto a substrate. A metal oxide deposited fibrous material comprising a substrate, fibers and metal oxide particles may be made using the method. The material may be a flexible and porous fibrous matrix on which metal oxide particles may be uniformly deposited on a surface thereof. In an exemplary embodiment, the invention is directed to an electrospun nanofibrous material on which electrosprayed photocatalytic metal oxide particles are uniformly deposited without agglomeration.
    Type: Application
    Filed: September 2, 2009
    Publication date: August 11, 2011
    Applicant: DREXEL UNIVERSITY
    Inventors: Yury Gogotsi, Byung-Yong Lee, Kris Behler, Richard Rest
  • Compositions and methods for preventing and treating anthrax diseases
    Patent number: 7588912
    Abstract: Compounds, methods for identifying compounds and methods for using compounds which modulate interaction of lethal factor and anthrolysin O in the treatment and prevention of anthrax diseases are provided.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: September 15, 2009
    Assignees: Regents of the University of California, Philadelphia Health and Education Corporation
    Inventors: Richard Rest, Michael Karin, Jin Mo Park
  • Compositions and methods for activating Toll-like receptor 4
    Patent number: 7521073
    Abstract: Methods for activating Toll-like receptor 4 via cholesterol-dependent cytolysins isolated from a Gram-positive bacteria are provided. In addition compositions containing an isolated cholesterol-dependent cytolysin or a fragment thereof or a mimetic of the cytolysin or fragment thereof and methods for use of such composition in inhibiting binding and/or interaction of Toll-like receptor 4 with endotoxin are provided. Methods for identifying modulators of Toll-like receptor 4 activation by a cholesterol-dependent cytolysin and use of such modulators in treatment of septicemia and/or septic shock are also provided.
    Type: Grant
    Filed: June 18, 2007
    Date of Patent: April 21, 2009
    Assignee: Philadelphia Health and Education Corporation
    Inventors: Richard Rest, Michael Karin, Jin Mo Park
  • Compositions and Methods for Activating Toll-like Receptor 4
    Publication number: 20070248706
    Abstract: Methods for activating Toll-like receptor 4 via cholesterol-dependent cytolysins isolated from a Gram-positive bacteria are provided. In addition compositions containing an isolated cholesterol-dependent cytolysin or a fragment thereof or a mimetic of the cytolysin or fragment thereof and methods for use of such composition in inhibiting binding and/or interaction of Toll-like receptor 4 with endotoxin are provided. Methods for identifying modulators of Toll-like receptor 4 activation by a cholesterol-dependent cytolysin and use of such modulators in treatment of septicemia and/or septic shock are also provided.
    Type: Application
    Filed: June 18, 2007
    Publication date: October 25, 2007
    Inventors: Richard Rest, Michael Karin, Jin Park
  • Compositions and methods for preventing and treating anthrax diseases
    Publication number: 20060204525
    Abstract: Compounds, methods for identifying compounds and methods for using compounds which modulate interaction of lethal factor and anthrolysin O in the treatment and prevention of anthrax diseases are provided.
    Type: Application
    Filed: October 12, 2005
    Publication date: September 14, 2006
    Inventors: Richard Rest, Michael Karin, Jin Park
  • Compositions and methods for activating toll-like receptor 4
    Publication number: 20060089305
    Abstract: Methods for activating Toll-like receptor 4 via cholesterol-dependent cytolysins isolated from a Gram-positive bacteria are provided. In addition compositions containing an isolated cholesterol-dependent cytolysin or a fragment thereof or a mimetic of the cytolysin or fragment thereof and methods for use of such composition in inhibiting binding and/or interaction of Toll-like receptor 4 with endotoxin are provided. Methods for identifying modulators of Toll-like receptor 4 activation by a cholesterol-dependent cytolysin and use of such modulators in treatment of septicemia and/or septic shock are also provided.
    Type: Application
    Filed: October 12, 2005
    Publication date: April 27, 2006
    Inventors: Richard Rest, Michael Karin, Jin Park