Abstract: A method of manufacturing a preform, the method including positioning at least one glass tube in a glass outer cladding to form a preform precursor, the glass tube comprising a first open end and a second open end, forming a preform from the preform precursor, and thermally treating at least one of the preform precursor and the preform. The thermally treating including sealing the first open end and the second open end of the glass tube to form a closed tube and heating and/or cooling the glass tube to manipulate gas pressure within the closed glass tube.

Abstract: A clearance control assembly for a gas turbine engine that defines an axial direction and a radial direction and includes a stage of rotor blades and a shroud hanger. The assembly includes a case configured to be positioned outward along the radial direction from the stage of rotor blades when installed in the gas turbine engine. The case is further configured to be engaged with the shroud hanger at a first location when installed in the gas turbine engine. The assembly also includes a baffle positioned outward along the radial direction from the case to define a chamber therebetween. The baffle has a forward end and an aft end. The forward end of the baffle is engaged with the case to form a first seal and the aft end of the baffle is engaged with the case to form a second seal. The baffle, the case, or both define an inlet to allow a fluid to enter the chamber and the case defines an outlet to allow the fluid to exit the chamber.

Abstract: Bacterial cultures are provided that comprise a modified Pseudomonas aeruginosa bacterium missing or deficient in two or more virulence factors. The two or more virulence factors can be selected from exotoxin A, hemolytic phospholipase C, phenazine-specific methyltransferase, alpha-1,3-rhamnosyltransferase, and 3-phosphoshikimate 1-carboxyvinyltransferase. Certain of the modified Pseudomonas aeruginosa bacteria are also missing or deficient in one or more alginate acetylation enzymes including the alginate O-acetyltransferases AlgI, AlgJ, AlgF, AlgX, and/or the C5-mannuronan epimerase AlgG. Methods of producing alginate are also provided along with compositions comprising alginate produced by the modified Pseudomonas aeruginosa bacteria.

Abstract: Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

Abstract: The present disclosure provides three-dimensional (3D) printing processes, apparatuses, software, and systems for the production of at least one desired 3D object. The 3D printer system (e.g., comprising a processing chamber, build module, or an unpacking station) described herein may retain a desired (e.g., inert) atmosphere around the material bed and/or 3D object at multiple 3D printing stages. The 3D printer described herein comprises one or more build modules that may have a controller separate from the controller of the processing chamber. The 3D printer described herein comprises a platform that may be automatically constructed. The invention(s) described herein may allow the 3D printing process to occur for a long time without operator intervention and/or down time.

Abstract: A system for communicating an impact sustained by a work machine moving at a worksite to a remote operator workstation for controlling the work machine through the remote operator workstation. The system includes a controller configured to obtain data associated with an acceleration of the work machine along one or more degrees of motion during a movement of the work machine at the worksite and derive an acceleration value based on the data. The controller is further configured to issue a notification of the impact of the work machine to the remote operator workstation through an output device of the remote operator workstation if the acceleration value exceeds a threshold acceleration value during the movement of the work machine.

Abstract: The present disclosure provides three-dimensional (3D) printing processes, apparatuses, software, and systems for controlling and/or treating gas borne debris in an atmosphere of a 3D printing system.

Abstract: The present disclosure provides three-dimensional (3D) printing processes, apparatuses, software, and systems for the production of at least one desired 3D object. The 3D printer system (e.g., comprising a processing chamber, build module, or an unpacking station) described herein may retain a desired (e.g., inert) atmosphere around the material bed and/or 3D object at multiple 3D printing stages. The 3D printer described herein comprises one or more build modules that may have a controller separate from the controller of the processing chamber. The 3D printer described herein comprises a platform that may be automatically constructed. The invention(s) described herein may allow the 3D printing process to occur for a long time without operator intervention and/or down time.

Abstract: An augmented reality, virtual reality, or other wearable apparatus comprises an eye tracking device comprising an image sensor, a lens, and one or more processors. In some embodiments, the lens comprises a marker, and the one or more processors are configured to receive an image from the image sensor, wherein the image shows the marker, determine a distance from the image sensor to the marker based on the image, and change a calibration parameter of an eye tracking algorithm based on the distance. In some embodiments, the one or more processors are configured to receive image data from the image sensor, wherein the image data corresponds to an image as observed through the lens, determine a level or pattern of pincushion distortion in the image based on the image data, and change a calibration parameter of an eye tracking algorithm based on the level or the pattern of pincushion distortion.

Abstract: An Internet of Things (IoT) network includes an orchestrator to issue service management requests, a service coordinator to identify components to participate in the service, and a component to perform a network service element. An IoT network includes an IoT device with service enumerator, contract enumerator, and join contract function. An IoT network apparatus includes permissions guide drafter for discovered peers, and permissions guide action executor. An IoT network apparatus includes floating service permissions guide drafter for discovered hosts, host hardware selector, floating service permissions guide executor, and service wallet value transferor. An IoT network apparatus includes permissions guide drafter for first and second discovered peers, parameter weight calculator, permissions guide term generator, and permissions guide action executor.

Abstract: Systems and methods are provided to create training data, validate, deploy and test artificial intelligence (AI) systems in a virtual development environment, incorporating virtual spaces, objects, machinery, devices, subsystems, and actual human action and behavior.

Abstract: A turbine blade tip shroud has a first cutter tooth extending from a tip rail from one of the upstream side and the downstream side of the tip rail and adjacent the leading edge of the body. The tip shroud also includes a second cutter tooth extending from the tip rail from the other side of the tip rail at a position axially distant from the first cutter tooth. The cutter teeth are thus axially offset. The tip shroud can be initially manufactured with this shape or may be modified from a used tip shroud having, for example, opposing cutter teeth near a leading edge of a body of the tip shroud. Various tip shroud surface profiles, which are expressed in terms of Cartesian coordinates, are also provided.

Abstract: A control system for a machine includes a chassis, an implement attached to the chassis, at least one sensor coupled to the chassis or the implement, and a controller in communication with the sensor. The controller is configured to receive one or more signals from the at least one sensor, determine a stabilization factor based on the one or more signals from the at least one sensor, and signal one or more actuators to control a movement and/or a position of the implement based at least in part on the stabilization factor.

Abstract: The present invention relates to a polypeptide comprising 7 ?-strands A, B, C, D, E, F, and G sequentially connected together by connecting chains of amino acids, and a first ?-helix sequentially located on the EF chain between ?-strands E and F, wherein the ?-strands are arranged so as to form a first ?-sheet comprising ?-strands A, B, D, and E, and a second ?-sheet comprising ?-strands C, F and G, said first and second ?-sheets being covalently bonded together so as to form a first Ig domain; wherein the EF chain between ?-strands E and F comprises the sequence X1-X2-X3-X4-K5H6 (SEQ ID NO:98), and X1, X3 and X4 are each independently any amino acid residue, characterized in that X2 is selected from the group consisting of A, G, I, V, L, R, S, T, Q, P, N, M, H, W, and pharmaceutically acceptable salts, stereoisomers, tautomers, solvates, and prodrugs thereof.

Abstract: A tip shroud includes a pair of opposed, axially extending wings configured to couple to an airfoil at a radially outer end thereof. The tip shroud also includes a tip rail extending radially from the pair of opposed, axially extending wings. Tip shroud surface profiles may be of the downstream and/or upstream side of the tip rail, a leading Z-notch of the tip shroud, and/or downstream radially inner surface of a wing. The surface profiles may have a nominal profile substantially in accordance with at least part of Cartesian coordinate values of X and Y, and perhaps Z and a thickness, set forth in a respective table. The radially inner surface of the wing may define a protrusion extending along the radially outer end of the airfoil, the suction side fillet, and a radial inner surface of the wing to an axial edge of the wing.

Abstract: A tip shroud may include a platform to couple to an airfoil having a pressure side and a suction side. A front tip rail and a rear tip rail extend radially from the platform with each including a downstream side, an upstream side, and an origin(s). Each of the downstream side and the upstream side of the rear tip rail and the downstream side of the front tip rail has a shape having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y, Z set forth in a respective table and originating at a selected origin. The Cartesian coordinate values are non-dimensional values of from 0% to 100% convertible to distances by multiplying the X, Y, Z values by a minimum rear tip rail X-wise extent expressed in units of distance. The X, Y, Z values are connected by lines to define each respective surface profile.

Abstract: An airfoil includes a root and a tip, which define a span of the airfoil therebetween. The airfoil also includes a leading edge and a trailing edge downstream of the leading edge along a flow direction. The leading edge and the trailing edge each extend across the span of the airfoil from the root to the tip. The airfoil further includes a pressure side surface and a suction side surface. The airfoil also includes a thermal barrier coating on the pressure side surface and the suction side surface. The thermal barrier coating includes a base layer and a top coat. A thickness of the base layer varies across each of the pressure side surface and the suction side surface with a maximum thickness of the base layer at the leading edge.

Abstract: A tip shroud includes a pair of opposed, axially extending wings configured to couple to an airfoil at a radially outer end thereof. The tip shroud also includes a tip rail extending radially from the pair of opposed, axially extending wings. Tip shroud surface profiles may be of the downstream and/or upstream side of the tip rail, a leading Z-notch of the tip shroud, and/or a downstream radially inner surface of a wing. The surface profiles may have a nominal profile substantially in accordance with at least part of Cartesian coordinate values of X and Y, and perhaps Z and a thickness, set forth in a respective table. The radially inner surface of the wing may define a protrusion extending along the radially outer end of the airfoil, the suction side fillet, and a radial inner surface of the wing to an axial edge of the wing.

Abstract: A turbine blade tip shroud has a first cutter tooth extending from a tip rail from one of the upstream side and the downstream side of the tip rail and adjacent the leading edge of the body. The tip shroud also includes a second cutter tooth extending from the tip rail from the other side of the tip rail at a position axially distant from the first cutter tooth. The cutter teeth are thus axially offset. The tip shroud can be initially manufactured with this shape or may be modified from a used tip shroud having, for example, opposing cutter teeth near a leading edge of a body of the tip shroud. Various tip shroud surface profiles, which are expressed in terms of Cartesian coordinates, are also provided.

Abstract: A tip shroud includes a pair of opposed, axially extending wings configured to couple to an airfoil at a radially outer end thereof. The tip shroud also includes a tip rail extending radially from the pair of opposed, axially extending wings. Tip shroud surface profiles may be of the downstream and/or upstream side of the tip rail, a leading Z-notch of the tip shroud, and/or downstream radially inner surface of a wing. The surface profiles may have a nominal profile substantially in accordance with at least part of Cartesian coordinate values of X and Y, and perhaps Z and a thickness, set forth in a respective table. The radially inner surface of the wing may define a protrusion extending along the radially outer end of the airfoil, the suction side fillet, and a radial inner surface of the wing to an axial edge of the wing.