Patents by Inventor Richard S. Lee
Richard S. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11961952Abstract: A secondary battery is provided for cycling between a charged and a discharged state, the secondary battery including a battery enclosure, an electrode assembly, carrier ions, a non-aqueous liquid electrolyte within the battery enclosure, and a set of electrode constraints. The set of electrode constraints includes a primary constraint system having first and second primary growth constraints and at least one primary connecting member, the first and second primary growth constraints separated from each other in the longitudinal direction, wherein the primary constraint array restrains growth of the electrode assembly in the longitudinal direction such that any increase in the Feret diameter of the electrode assembly in the longitudinal direction over 20 consecutive cycles of the secondary battery is less than 20%.Type: GrantFiled: September 6, 2022Date of Patent: April 16, 2024Assignee: Enovix CorporationInventors: Robert S. Busacca, Ashok Lahiri, Murali Ramasubramanian, Bruno A. Valdes, Gardner Cameron Dales, Christopher J. Spindt, Geoffrey Matthew Ho, Harrold J. Rust, III, James D. Wilcox, John F. Varni, Kim Han Lee, Nirav S. Shah, Richard J. Contreras, Lynn Van Erden, Vladimir Dioumaev
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Patent number: 11235294Abstract: A receptacle comprises opposed members, a plurality of chambers having perimeter walls defined by seals formed between the opposed members and portals interconnecting the chambers, and a rigid frame supporting the opposed members at their peripheral edges. The frame comprises a front frame portion and a rear frame portion, and the peripheral edges of the opposed members are retained between the front and rear frame portions. An inlet port extends between the front and rear frame portions and is in fluid communication with one of the chambers.Type: GrantFiled: December 27, 2018Date of Patent: February 1, 2022Assignee: GEN-PROBE INCORPORATEDInventors: Scott S. Breidenthal, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 11235295Abstract: A method of processing a sample in a receptacle comprising a plurality of chambers. Each of the chambers is connected to at least one other chamber by a portal and at least a first one of the chambers is formed of a flexible material. The method includes the steps of causing gas bubbles contained in the first chamber to accumulate in a portion of the first chamber, applying a compressive external force to the first chamber to cause some or all of the liquid contents of the first chamber to flow into an interconnected second chamber through a portal connecting the first and second chambers; and preventing the gas bubbles accumulated in a portion of the first chamber from flowing through the portal into the second chamber.Type: GrantFiled: December 27, 2018Date of Patent: February 1, 2022Assignees: GEN-PROBE INCORPORATED, QUALIGEN, INC.Inventors: Scott S. Breidenthal, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 10744469Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: GrantFiled: December 12, 2008Date of Patent: August 18, 2020Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 10745737Abstract: Methods, reagents, and kits for the reversible immobilization of glycoproteins to a solid support, the release and capture of a glycan portion of the glycoprotein, and the subsequent release and capture of the polypeptide portion of the glycoprotein are provided. The disclosure also provides suitable solid support materials, surface chemistries, and devices for use in the disclosed methods. The methods, reagents, kits, and devices provided herein are useful for the analysis of protein glycosylation, for example, in a diagnostic context, in the context of proteoglycomics, and in the context of producing glycosylated proteins for therapeutic purposes.Type: GrantFiled: November 7, 2013Date of Patent: August 18, 2020Assignee: Children's Medical Center CorporationInventors: Richard S. Lee, Hui Zhou
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Patent number: 10688458Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: GrantFiled: April 12, 2017Date of Patent: June 23, 2020Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Publication number: 20190126220Abstract: A method of processing a sample in a receptacle comprising a plurality of chambers. Each of the chambers is connected to at least one other chamber by a portal and at least a first one of the chambers is formed of a flexible material.Type: ApplicationFiled: December 27, 2018Publication date: May 2, 2019Applicants: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. BREIDENTHAL, Richard S. LEE, Norman C. NELSON, Matthew J. SCOTT, Jason A. TAYLOR
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Publication number: 20190126219Abstract: A receptacle comprises opposed members, a plurality of chambers having perimeter walls defined by seals formed between the opposed members and portals interconnecting the chambers, and a rigid frame supporting the opposed members at their peripheral edges. The frame comprises a front frame portion and a rear frame portion, and the peripheral edges of the opposed members are retained between the front and rear frame portions. An inlet port extends between the front and rear frame portions and is in fluid communication with one of the chambers.Type: ApplicationFiled: December 27, 2018Publication date: May 2, 2019Applicants: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. BREIDENTHAL, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Publication number: 20190002857Abstract: Polynucleotide sequences are provided encoding a thermostable cellulase and directing its increased expression are provided, and the use of the thermostable cellulase in hydraulic fracturing methods and the treatment of flowback fluids.Type: ApplicationFiled: July 6, 2018Publication date: January 3, 2019Inventors: Xuqiu Tan, Kenneth E. Barrett, Richard S. Lee
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Patent number: 10017754Abstract: Polynucleotide sequences are provided encoding a thermostable cellulase and directing its increased expression are provided, and the use of the thermostable cellulase in hydraulic fracturing methods and the treatment of flowback fluids.Type: GrantFiled: March 12, 2013Date of Patent: July 10, 2018Assignee: BASF Enzymes LLCInventors: Xuqiu Tan, Kenneth E. Barrett, Richard S. Lee
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Patent number: 9744506Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.Type: GrantFiled: April 3, 2013Date of Patent: August 29, 2017Assignee: GEN-PROBE INCORPORATEDInventors: Sara H. Fan, Richard S. Lee
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Publication number: 20170218431Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: ApplicationFiled: April 12, 2017Publication date: August 3, 2017Applicants: GEN-PROBE INCORPORATED, QUALIGEN, INC.Inventors: Scott S. Breidenthal, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Publication number: 20160003842Abstract: A system including a device with at least one processor and memory storing computer-executable instructions that, when executed by the at least one processor, perform a method of identifying glycopeptides in a sample, the method including, analyzing a mass spectrum of the sample to identify at least one portion of the mass spectrum having at least one characteristic of mass spectra indicative of presence of glycopeptides, identifying the glycopeptides in the sample based on the at least one identified portion; and analyzing at least one glycopeptide of the identified glycopeptides.Type: ApplicationFiled: February 20, 2014Publication date: January 7, 2016Applicant: Children's Medical Center CorporationInventors: Richard S. Lee, John Froehlich
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Publication number: 20150291996Abstract: Methods, reagents, and kits for the reversible immobilization of glycoproteins to a solid support, the release and capture of a glycan portion of the glycoprotein, and the subsequent release and capture of the polypeptide portion of the glycoprotein are provided. The disclosure also provides suitable solid support materials, surface chemistries, and devices for use in the disclosed methods. The methods, reagents, kits, and devices provided herein are useful for the analysis of protein glycosylation, for example, in a diagnostic context, in the context of proteoglycomics, and in the context of producing glycosylated proteins for therapeutic purposes.Type: ApplicationFiled: November 7, 2013Publication date: October 15, 2015Inventors: Richard S. Lee, Hui Zhou
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Publication number: 20150235326Abstract: Operation of a business that is involved in the preparation or supply of pollutant capture sorbent products within a master limited partnership (MLP) structure is facilitated by the methods, systems and computer program products described herein. In one embodiment, a method for operating a business involving carbon-based mercury capture sorbent product may include performing at least one processing or supply activity in connection with preparing or supplying mercury capture sorbent product comprising sorbent particles with a porous carbonaceous structure comprising carbon from coal, receiving revenue as a consequence of performing the at least one activity, and distributing at least a portion of the revenue to at least one MLP unit holder pursuant to provisions of a MLP agreement.Type: ApplicationFiled: February 20, 2015Publication date: August 20, 2015Inventors: Ronald Peter Owen Hansen, Richard S. Lee
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Publication number: 20150072397Abstract: Polynucleotide sequences are provided encoding a thermostable cellulase and directing its increased expression are provided, and the use of the thermostable cellulase in hydraulic fracturing methods and the treatment of flowback fluids.Type: ApplicationFiled: March 12, 2013Publication date: March 12, 2015Inventors: Xuqiu Tan, Kenneth E. Barrett, Richard S. Lee
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Patent number: 8765367Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: GrantFiled: December 12, 2008Date of Patent: July 1, 2014Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Sara H. Fan, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 8735055Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: GrantFiled: December 12, 2008Date of Patent: May 27, 2014Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Sara H. Fan, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 8491178Abstract: A receptacle having interconnected chambers arranged to permit multiple process steps to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.Type: GrantFiled: March 7, 2012Date of Patent: July 23, 2013Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Sara H. Fan, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor
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Patent number: 8480976Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.Type: GrantFiled: July 13, 2011Date of Patent: July 9, 2013Assignees: Gen-Probe Incorporated, Qualigen, Inc.Inventors: Scott S. Breidenthal, Sara H. Fan, Richard S. Lee, Norman C. Nelson, Matthew J. Scott, Jason A. Taylor