Patents by Inventor Richard S. Williams
Richard S. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7641679Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: October 17, 2005Date of Patent: January 5, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams
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Patent number: 7546004Abstract: A photonic interconnect system avoids high capacitance electric interconnects by using optical signals to communicate data between devices. The system can provide massively parallel information output by mapping logical addresses to frequency bands, so that modulation of a selected frequency band can encode information for a specific location corresponding to the logical address. Wavelength-specific directional couplers, modulators, and detectors for the photonic interconnect system can be efficiently fabricated at defects in a photonic bandgap crystal. The interconnect system can be used for both classical and quantum information processing.Type: GrantFiled: January 11, 2008Date of Patent: June 9, 2009Assignee: Hewlett-Packard Development Company, L.P.Inventors: Raymond G. Beausoleil, Philip J. Kuekes, William J. Munro, Timothy P. Spiller, Richard S. Williams, Sean D. Barrett
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Patent number: 7343059Abstract: A photonic interconnect system avoids high capacitance electric interconnects by using optical signals to communicate data between devices. The system can provide massively parallel information output by mapping logical addresses to frequency bands, so that modulation of a selected frequency band can encode information for a specific location corresponding to the logical address. Wavelength-specific directional couplers, modulators, and detectors for the photonic interconnect system can be efficiently fabricated at defects in a photonic bandgap crystal.Type: GrantFiled: October 11, 2003Date of Patent: March 11, 2008Assignee: Hewlett-Packard Development Company, L.P.Inventors: Raymond G. Beausoleil, Philip J. Kuekes, William J. Munro, Timothy P. Spiller, Richard S. Williams, Sean D. Barrett
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Publication number: 20070299433Abstract: A medical device for treating esophageal tissue comprises a catheter, a balloon, placeable within the esophagus of the patient, and a refrigerant. The refrigerant is deliverable into the interior of the balloon so to place the balloon into an expanded, cooled state so that the balloon can press against and cool esophageal tissue. In other examples the medical device may include means for limiting radial expansion of the balloon.Type: ApplicationFiled: June 26, 2007Publication date: December 27, 2007Applicant: C2 TherapeuticsInventors: Richard S. Williams, Peter Garcia-Meza
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Patent number: 7195639Abstract: An intraluminal grafting system having a balloon catheter assembly, a capsule catheter assembly and capsule jacket assembly is used for deploying in the vessel of an animal body a bifurcated graft having a plurality of attachment systems. The deployment catheters contain an ipsilateral capsule assembly, a contralateral capsule assembly and a distal capsule assembly, wherein the attachment systems of the bifurcated graft are disposed within the three capsule assemblies. A removable sheath of the capsule jacket assembly covers the bifurcated graft and capsule assemblies to provide a smooth transition along the length of the deployment catheters. The bifurcated graft is comprised of a main tubular member and two tubular legs, having attachment systems with wall engaging members secured to the superior end of the main tubular member and the inferior ends of the tubular legs. An inflatable membrane configured on the balloon catheter is used to firmly implant the attachment systems within the vessel.Type: GrantFiled: January 23, 2004Date of Patent: March 27, 2007Assignee: Endovascular Technologies, Inc.Inventors: Dinah B. Quiachon, Alec A. Piplani, Richard S. Williams, Steve G. Baker, Peter K. Johansson
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Patent number: 7118594Abstract: An apparatus for repairing a vessel using a multicapsule catheter having first, second and third capsules for releasably retaining each terminal end of a bifurcated graft. The method for repairing the vessel includes the steps of performing a surgical technique to gain remote access to the vessel, advancing the multicapsule catheter within the vessel and releasing the bifurcated graft within the vessel to thereby repair the vessel.Type: GrantFiled: September 28, 2004Date of Patent: October 10, 2006Assignee: Endovascular Technologies, Inc.Inventors: Dinah B. Quiachon, Alec A. Piplani, Steve G. Baker, Ronald G. Williams, Richard S. Williams, Kenneth L. Osborn, Ted W. Layman, Peter K. Johansson
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Patent number: 7081112Abstract: The invention provides techniques and devices for treating atherosclerotic disease using controlled cryogenic cooling, often in combination with angioplusty. The efficacy of endolusninal cryogenic cooling is enhanced by cooling of target tissues using an insulated cryogenic balloon, the lnsulation ideally comprising a fluid which undergoes a phase change at a predetermined temperature. A combination cryogenic/angioplasty catheter avoids exchange procedures between dilation of a stenotic region within a vessel wall and the application of cryogenic cooling. The combination angioplasty/cryogenic cooling catheter may cool the diseased blood vessel before, during, and/or after dilation. Controlled cooling of the vessel wall may change its mechanical properties, weakening the vessel and allowing it to be expanded at a much lower pressure than with conventional uncooled angioplasty.Type: GrantFiled: August 7, 2002Date of Patent: July 25, 2006Assignee: Cryovascular Systems, Inc.Inventors: James Joye, Kristine Tatsutani, Ronald Williams, Richard S. Williams
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Patent number: 7060062Abstract: Devices, systems, and methods controllably cool blood vessels and other body lumens. The blood vessel will often be treated for atherosclerotic or other diseases by inflating a balloon so as to engage the surrounding luminal wall. Controlled cooling of the balloon effected by a change in phase of a cryogenic fluid within the balloon typically a change from a liquid phase to a gas phase can be provided with a controlled, gradual inflation of the balloon. A single control system can be used for any of a variety of alternative selectable balloon catheters having significantly differing cooling fluid flow characteristics.Type: GrantFiled: June 4, 2003Date of Patent: June 13, 2006Assignee: Cryo Vascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Glen Reuschling
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Patent number: 6972015Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: February 23, 2004Date of Patent: December 6, 2005Assignee: CryoVascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams
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Patent number: 6786901Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: March 21, 2002Date of Patent: September 7, 2004Assignee: CryoVascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams
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Publication number: 20040167505Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: ApplicationFiled: February 23, 2004Publication date: August 26, 2004Applicant: CryoVascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams
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Publication number: 20040153143Abstract: An intraluminal grafting system having a balloon catheter assembly, a capsule catheter assembly and capsule jacket assembly is used for deploying in the vessel of an animal body a bifurcated graft having a plurality of attachment systems. The deployment catheters contain an ipsilateral capsule assembly, a contralateral capsule assembly and a distal capsule assembly, wherein the attachment systems of the bifurcated graft are disposed within the three capsule assemblies. A removable sheath of the capsule jacket assembly covers the bifurcated graft and capsule assemblies to provide a smooth transition along the length of the deployment catheters. The bifurcated graft is comprised of a main tubular member and two tubular legs, having attachment systems with wall engaging members secured to the superior end of the main tubular member and the inferior ends of the tubular legs. An inflatable membrane configured on the balloon catheter is used to firmly implant the attachment systems within the vessel.Type: ApplicationFiled: January 23, 2004Publication date: August 5, 2004Inventors: Dinah B. Quiachon, Alec A. Piplani, Richard S. Williams, Steve G. Baker, Peter K. Johansson
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Patent number: 6682557Abstract: An intraluminal grafting system having a balloon catheter assembly, a capsule catheter assembly and capsule jacket assembly is used for deploying in the vessel of an animal body a bifurcated graft having a plurality of attachment systems. The deployment catheters contain an ipsilateral capsule assembly, a contralateral capsule assembly and a distal capsule assembly, wherein the attachment systems of the bifurcated graft are disposed within the three capsule assemblies. A removable sheath of the capsule jacket assembly covers the bifurcated graft and capsule assemblies to provide a smooth transition along the length of the deployment catheters. The bifurcated graft is comprised of a main tubular member and two tubular legs, having attachment systems with wall engaging members secured to the superior end of the main tubular member and the inferior ends of the tubular legs. An inflatable membrane configured on the balloon catheter is used to firmly implant the attachment systems within the vessel.Type: GrantFiled: December 18, 2001Date of Patent: January 27, 2004Assignee: Endovascular Technologies, Inc.Inventors: Dinah B. Quiachon, Alec A. Piplani, Richard S. Williams, Steve G. Baker, Peter K. Johansson
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Patent number: 6663666Abstract: An apparatus for repairing a vessel using a multicapsule catheter having first, second and third capsules for releasably retaining each terminal end of a bifurcated graft. The method for repairing the vessel includes the steps of performing a surgical technique to gain remote access to the vessel, advancing the multicapsule catheter within the vessel and releasing the bifurcated graft within the vessel to thereby repair the vessel.Type: GrantFiled: May 22, 2001Date of Patent: December 16, 2003Assignee: Endovascular Technologies, Inc.Inventors: Dinah B. Quiachon, Alec A. Piplani, Steve G. Baker, Ronald G. Williams, Richard S. Williams, Kenneth L. Osborn, Ted W. Layman
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Publication number: 20030109912Abstract: Techniques and devices for treating atherosclerotic disease use controlled cryogenic cooling, often in combination with angioplasty and/or stenting. A combination cryogenic/angioplasty catheter may cool the diseased blood vessel before, during, and/or after dilation. Controlled cooling of the vessel wall reduces actual/observed hyperplasia as compared to conventional uncooled angioplasty. Similar reductions in restenosis may be provided for other primary treatments of the blood vessel, including directional arthrectomy, rotational arthrectomy, laser angioplasty, stenting, and the like. Cooling of vessel wall tissues will often be performed through plaque, and the cooling process will preferably take the thermodynamic effects of the plaque into account.Type: ApplicationFiled: August 7, 2002Publication date: June 12, 2003Applicant: CryoVascular Systems, Inc.Inventors: James Joye, Kristine Tatsutani, Ronald Williams, Richard S. Williams
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Patent number: 6514245Abstract: Improved devices, systems, and methods for inhibiting hyperplasia in blood vessels provide controlled and safe cryotherapy treatment of a target portion within a body lumen of a patient. Efficacy of endoluminal cryogenic cooling can be enhanced by limiting cooling of target tissues using a thermal barrier disposed between a dual balloon cryotherapy catheter. Containment of both balloons can be monitored by applying a vacuum within a space between the first and second balloons, and by coupling the vacuum space to a fluid shutoff so as to inhibit flow of cryogenic fluid in response to a change in the vacuum space. Controlled cooling of the vessel can be improved by use of a nebulizer in fluid communication with a cryogenic liquid supply lumen and a gas supply lumen.Type: GrantFiled: July 19, 2000Date of Patent: February 4, 2003Assignee: Cryovascular Systems, Inc.Inventors: Ronald Williams, James Joye, Richard S. Williams, Timothy D. Holland
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Publication number: 20020183731Abstract: Improved devices, systems, and methods for inhibiting hyperplasia in blood vessels provide controlled and safe cryotherapy treatment of a target portion within a body lumen of a patient. Efficacy of endoluminal cryogenic cooling can be enhanced by limiting cooling of target tissues using a thermal barrier disposed between a dual balloon cryotherapy catheter. Containment of both balloons can be monitored by applying a vacuum within a space between the first and second balloons, and by coupling the vacuum space to a fluid shutoff so as to inhibit flow of cryogenic fluid in response to a change in the vacuum space. Controlled cooling of the vessel can be improved by use of a nebulizer in fluid communication with a cryogenic liquid supply lumen and a gas supply lumen.Type: ApplicationFiled: July 11, 2002Publication date: December 5, 2002Applicant: CRYOVASCULAR SYSTEMS, INC., A Delaware CorporationInventors: Timothy D. Holland, James Joye, Ronald Williams, Richard S. Williams
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Patent number: 6468297Abstract: Techniques and devices for treating atherosclerotic disease use controlled cryogenic cooling, often in combination with angioplasty and/or stenting. A combination cryogenic/angioplasty catheter may cool the diseased blood vessel before, during, and/or after dilation. Controlled cooling of the vessel wall reduces actual/observed hyperplasia as compared to conventional uncooled angioplasty. Similar reductions in restenosis may be provided for other primary treatments of the blood vessel, including directional arthrectomy, rotational arthrectomy, laser angioplasty, stenting, and the like. Cooling of vessel wall tissues will often be performed through plaque, and the cooling process will preferably take the thermodynamic effects of the plaque into account.Type: GrantFiled: February 23, 2000Date of Patent: October 22, 2002Assignee: Cryovascular Systems, Inc.Inventors: Ronald Williams, James Joye, Richard S. Williams, Kristine Tatsutani
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Patent number: 6454796Abstract: A bifurcated vascular graft having a tubular trunk with an inner diameter. Tubular limbs having respective inner diameters extend longitudinally from the trunk, and the diameter of at least one of the limbs is unequal to half the trunk diameter. In one embodiment, the graft is flared such that the combined diameters of the limbs exceed the diameter of the trunk. In another embodiment, the graft is tapered such that the diameter of the trunk exceeds the combined diameters of the limbs. In a third embodiment, the limb diameters are unequal to one another.Type: GrantFiled: May 5, 2000Date of Patent: September 24, 2002Assignee: Endovascular Technologies, Inc.Inventors: Kimberley Barkman, Peter Ma, Richard S. Williams
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Patent number: 6432102Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: March 15, 1999Date of Patent: August 13, 2002Assignee: Cryovascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams