Patents by Inventor Richard Sayre

Richard Sayre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130224822
    Abstract: Genetically engineered algae strains for biofuels and bioproduct production have improved iron utilization including iron uptake and storage, and exhibit improved growth characteristics, magnetic separation, and magnetic hysteresis induced cell lysis. Pond production algal strain embodiments with high iron scavenging capabilities limit iron availability to contaminating microorganisms and invading species. Accumulation of high iron and other paramagnetic elements content in the form of ferritin enhances the cells magnetic susceptibility improving efficiency of magnetic separation and magnetic hysteresis induced cell lysis. Several genes of the embodiments are capable of improving iron acquisition including the ferritin gene fer1, iron transport gene fea1, and iron reductase gene fre1.
    Type: Application
    Filed: July 7, 2011
    Publication date: August 29, 2013
    Inventors: Richard Sayre, Brad Postier
  • Publication number: 20130059334
    Abstract: The present invention generally relates to the production of industrially relevant quantities of selenoprotein enzymes in eukaryotic cell cultures. More specifically, the present invention generally relates to the production of such enzymes wherein one or more catalytic cysteine or serine residues are mutagenically replaced by selenocysteine.
    Type: Application
    Filed: June 28, 2012
    Publication date: March 7, 2013
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Richard Sayre, Hangsik Moon
  • Patent number: 8236936
    Abstract: The present invention generally relates to the production of industrially relevant quantities of selenoprotein enzymes in eukaryotic cell cultures. More specifically, the present invention generally relates to the production of such enzymes wherein one or more catalytic cysteine or serine residues are mutagenically replaced by selenocysteine.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: August 7, 2012
    Assignee: Ohio State University
    Inventors: Richard Sayre, Hangsik Moon
  • Publication number: 20120183572
    Abstract: The present invention is to a safe, biodegradable trace metal binding system that effectively delivers chromium, cobalt, copper, iron, manganese, molybdenum, selenium and zinc to animals. The method of preparing an animal foodstuff composition involves the steps of: providing transgenic algal cells comprising a nucleotide sequence, the nucleotide sequence being capable of expressing a non-native metal-binding protein in the transgenic algal cells; binding the metal-binding protein with at least one metal so as to produce a metal-bound adduct of the metal-binding protein; and admixing the metal-bound adduct with animal foodstuff. The invention is also to a animal foodstuff composition comprising animal foodstuff and transgenic algal cells expressing a non-native metal-binding protein in the transgenic algal cells, such that the transgenic algal cells contain the metal-binding protein and the metal-binding protein being bound to a metal.
    Type: Application
    Filed: August 9, 2004
    Publication date: July 19, 2012
    Applicants: Phycotransgenics L.L.C., The Ohio State University Research Foundation
    Inventors: Richard Sayre, Richard Wagner
  • Publication number: 20100159511
    Abstract: The present invention generally relates to the production of industrially relevant quantities of selenoprotein enzymes in eukaryotic cell cultures. More specifically, the present invention generally relates to the production of such enzymes wherein one or more catalytic cysteine or serine residues are mutagenically replaced by selenocysteine.
    Type: Application
    Filed: June 21, 2006
    Publication date: June 24, 2010
    Applicant: OHIO STATE UNIVERSITY
    Inventors: Richard Sayre, Hangsik Moon
  • Publication number: 20050281840
    Abstract: The present invention is to a safe, biodegradable trace metal binding system that effectively delivers chromium, cobalt, copper, iron, manganese, molybdenum, selenium and zinc to animals. The method of preparing an animal foodstuff composition involves the steps of: providing transgenic algal cells comprising a nucleotide sequence, the nucleotide sequence being capable of expressing a non-native metal-binding protein in the transgenic algal cells; binding the metal-binding protein with at least one metal so as to produce a metal-bound adduct of the metal-binding protein; and admixing the metal-bound adduct with animal foodstuff. The invention is also to a animal foodstuff composition comprising animal foodstuff and transgenic algal cells expressing a non-native metal-binding protein in the transgenic algal cells, such that the transgenic algal cells contain the metal-binding protein and the metal-binding protein being bound to a metal.
    Type: Application
    Filed: August 9, 2004
    Publication date: December 22, 2005
    Applicants: The Ohio State University Research Foundation, Phycotransgenics L.L.C.
    Inventors: Richard Sayre, Richard Wagner
  • Patent number: 6932980
    Abstract: The present invention is to a safe, biodegradable trace metal binding system that effectively delivers chromium, cobalt, copper, iron, manganese, molybdenum, selenium and zinc to animals. The method of preparing an animal foodstuff composition involves the steps of: providing transgenic algal cells comprising a nucleotide sequence, the nucleotide sequence being capable of expressing a non-native metal-binding protein in the transgenic algal cells; binding the metal-binding protein with at least one metal so as to produce a metal-bound adduct of the metal-binding protein; and admixing the metal-bound adduct with animal foodstuff. The invention is also to a animal foodstuff composition comprising animal foodstuff and transgenic algal cells expressing a non-native metal-binding protein in the transgenic algal cells, such that the transgenic algal cells contain the metal-binding protein and the metal-binding protein being bound to a metal.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: August 23, 2005
    Inventors: Richard Sayre, Richard Wagner