Patents by Inventor Richard Schneiderman

Richard Schneiderman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR IMPROVING CELL LINE ACTIVITY IN IMMUNOISOLATION DEVICES
    Publication number: 20090110669
    Abstract: Methods for maintaining and improving the secretory activity of cells housed in immunoisolation devices.
    Type: Application
    Filed: January 5, 2009
    Publication date: April 30, 2009
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Richard Schneiderman, Revati J. Tatake, Randall Wilber Barton
  • Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
    Publication number: 20070009498
    Abstract: Unique multifunctional nucleotide expression cassettes comprising a nucleotide sequence encoding a human protease driven by a glucose-regulatable promoter, a nucleotide sequence encoding human proinsulin having sites at its B-C and C-A junctions altered to permit cleavage by the human protease, and a CMV promoter driving the transcription of the nucleotide sequence encoding the human proinsulin, such cassettes optionally having polyadenylation sequences after each structural gene and the nucleotide sequence encoding human proinsulin optionally carrying an H10D variant, and cells transformed thereby.
    Type: Application
    Filed: January 17, 2006
    Publication date: January 11, 2007
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Revati Tatake, Richard Schneiderman, Randall Barton
  • Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
    Patent number: 7045346
    Abstract: Unique multifunctional nucleotide expression cassettes comprising a nucleotide sequence encoding a human protease driven by a glucose-regulatable promoter, a nucleotide sequence encoding human proinsulin having sites at its B-C and C-A junctions altered to permit cleavage by the human protease, and a CMV promoter driving the transcription of the nucleotide sequence encoding the human proinsulin, such cassettes optionally having polyadenylation sequences after each structural gene and the nucleotide sequence encoding human proinsulin optionally carrying an H10D variant, and cells transformed thereby.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: May 16, 2006
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Revati J. Tatake, Richard Schneiderman, Randall Wilber Barton
  • Methods for improving cell line activity in immunoisolation devices
    Publication number: 20060029584
    Abstract: Methods for maintaining and improving the secretory activity of cells housed in immunoisolation devices.
    Type: Application
    Filed: September 27, 2005
    Publication date: February 9, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Richard Schneiderman, Revati Tatake, Randall Barton
  • Mini-Ad vector for immunization
    Publication number: 20040208846
    Abstract: The present invention provides a method for treating a disorder such as hemophilia. A method of treating hemophilia in a mammal by administering recombinant virus virions comprising a nucleotide sequence having an adenoviral inverted terminal repeat fusion sequence, a packaging signal, a transcriptional control region, and a nucleic acid encoding a therapeutic protein such as FVIII. In addition, the DNA molecule does not encode an adenoviral protein. It is preferred that the virions be administered to the mammal under conditions that result in the expression of the therapeutic protein at a level that provides a therapeutic effect in said mammal.
    Type: Application
    Filed: June 15, 2004
    Publication date: October 21, 2004
    Inventors: Wei-Wei Zhang, Ramon Alemany, Yifan Dai, Steven Josephs, Cristina Balague, David Ayares, Richard Schneiderman
  • Minimal adenoviral vector
    Publication number: 20030192066
    Abstract: This invention is related to adenoviral (Ad) vectors and their applications in the field of genetic medicine, including gene transfer, gene therapy, and gene vaccination. More specifically, this invention is related to the Ad vectors that carry the minimal cis-element of the Ad genome (mini-Ad vector) and are capable of delivering transgenes and/or heterologous DNA up to 36 kb. The generation and propagation of the mini-Ad vectors require trans-complementation of a packaging-attenuated and replication-defective helper Ad (helper) in an Ad helper cell line.
    Type: Application
    Filed: May 28, 2002
    Publication date: October 9, 2003
    Applicant: GenStar Therapeutics Corp.
    Inventors: Wei-Wei Zhang, Ramon Alemany, Yifan Dai, Steven Josephs, Cristina Balague, David Ayares, Richard Schneiderman
  • Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
    Publication number: 20030032144
    Abstract: Unique multifunctional nucleotide expression cassettes comprising a nucleotide sequence encoding a human protease driven by a glucose-regulatable promoter, a nucleotide sequence encoding human proinsulin having sites at its B-C and C-A junctions altered to permit cleavage by the human protease, and a CMV promoter driving the transcription of the nucleotide sequence encoding the human proinsulin, such cassettes optionally having polyadenylation sequences after each structural gene and the nucleotide sequence encoding human proinsulin optionally carrying an H10D variant, and cells transformed thereby.
    Type: Application
    Filed: June 10, 2002
    Publication date: February 13, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Revati J. Tatake, Richard Schneiderman, Randall Wilber Barton
  • Methods for improving cell line activity in immunoisolation devices
    Publication number: 20030012772
    Abstract: Methods for maintaining and improving the secretory activity of cells housed in immunoisolation devices.
    Type: Application
    Filed: June 10, 2002
    Publication date: January 16, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Richard Schneiderman, Revati J. Tatake, Randall Wilber Barton