Patents by Inventor Richard Scott Jope

Richard Scott Jope has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of bisindolylmaleimide compounds to induce Fas-mediated apoptosis
    Patent number: 6284783
    Abstract: The present invention provides a method of inducing apoptosis in target cells of a subject by administering, to the subject a pharmaceutically effective amount of at least one compound of the formula: wherein: R1 is hydrogen, C1-C12 alkyl, C1-C12 substituted alkyl, C3-C7 heterocycle, or C3-C7 substituted heterocycle, R2 and R3 are independently H or C1-C12 alkyl, and the pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, wherein following the administration of the compound of Formula I, the target cell is caused to undergo apoptosis.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: September 4, 2001
    Assignee: The UAB Research Foundation
    Inventors: Tong Zhou, Richard Scott Jope