Abstract: The disclosed embodiments concern methods, apparatus, systems and computer program products for determining the presence or absence of repeat expansions of interest, including repeat expansions of repeat sequences that are medically significant. Some embodiments provide methods for identifying and calling medically relevant repeat expansions using anchored reads. An anchored read is a paired end read that is unaligned to a repeat sequence under consideration, but it is paired with an anchor read that is aligned to or near the repeat sequence. Some embodiments use both anchor and anchored reads to determine the presence or absence of the repeat expansions. System, apparatus, and computer program products are also provided for determining repeat expansion implementing the methods disclosed.

Abstract: The invention provides processes that significantly reduce acid consumption while maintaining efficient leach recovery of copper from oxide and acid consuming ores. The invention provides a hydrometallurgical process that reduces acid required for leaching in the presence of a solid ion exchange media. The presence of the ion exchanger leads to copper extraction from solution into the ion exchange phase, the removal of the copper from solution shifts the dissolved copper equilibrium, enabling additional copper dissolution at weak acidities where normally the leaching equilibrium would be hindered. In select embodiments, the process is not reliant on an external neutralising agent to control pH but rather on the acid consuming characteristic of the ore being processed and a limit to the amount of acid added. At the pH at which the leach is controlled, iron (if present) is predominantly present as the ferrous ion, which has a lower affinity for the resin than copper.

Abstract: In order to reduce torsional vibrations in a drive including a torque converter with a turbine and impeller, clutch slip speed of the drive is adjusted by manipulation of clutch pressure. This may be done in either closed loop mode or open loop mode by setting the clutch pressure to a predetermined value or continuously adjusting clutch pressure. Pressure is adjusted to produce a positively sloped function of sensed total torque of the clutch and turbine over the clutch slip speed. This produces extended service life of the drive train components, greater efficiency of the torque converter, and smoother operation of the drive.

Abstract: The present invention relates to a replaceable battery module for an electrically driven vehicle, with at least one bracket that can be detachably arranged on a bearing structure of the motor vehicle, and carries at least one battery unit.

Abstract: Systems and methods of managing workload at a data center are disclosed. An example method may include actively managing workload at a data center to realize energy savings. The method may also include providing excess power generated for the data center onto a utility grid.

Abstract: The invention relates to a device for sanding a predetermined impression into a workpiece. The device has a pattern belt positioned inside the area formed by a sanding belt. A pad is positioned inside the area formed by the pattern belt. A raised pattern is formed on the outer surface of the pattern belt. In use, the pad contacts the pattern belt, urging the raised pattern of the pattern belt to contact the sanding belt. The portion of the sanding belt contacted by the pattern belt is urged toward the workpiece so that the predetermined impression is sanded into the workpiece.

Abstract: The present disclosure provides method, systems, and devices for adjusting an arch of teeth. An appliance includes a removable shell formed of a first material having a number of cavities formed therein, wherein the number of cavities are shaped to receive teeth of a patient, and an arch element extending from the removable shell in a lingual direction and across at least a portion of the arch width of the removable shell, wherein the arch element is designed to expand an arch of the teeth of the patient, wherein the arch element has a width specific to a stage of a treatment plan.

Abstract: The invention relates to a device and method for using same for sanding a predetermined impression into a workpiece. The device has a pattern belt positioned inside the area formed by a sanding belt. A pad is positioned inside the area formed by the pattern belt. A raised pattern is formed on the outer surface of the pattern belt. In use, the pad is selectively controlled to contact the pattern belt, thereby urging the raised pattern of the pattern belt to contact the sanding belt. The portion of the sanding belt contacted by the pattern belt is urged toward the workpiece so that the predetermined impression is sanded into the workpiece.

Abstract: An opening and/or closing device for a movable, flexurally rigid and at least regionally transparent wall element of a motor vehicle is provided. The device includes at least one supporting arm and at least one supporting body. The supporting arm and the supporting body encompass a first end that faces the wall element and is pivoted to the wall element, and encompass a second end that faces away from the wall element and is pivoted to a vehicle structure. By turning the supporting arm and the supporting body, the wall element is moved from an open functional position, in which a vehicle interior is accessible from outside for entry and/or egress and in which the wall element is situated in a frontal area of the motor vehicle, into a closed functional position, in which the vehicle interior is sealed to the outside by the wall element.

Abstract: In order to reduce torsional vibrations in a drive including a torque converter with a turbine and impeller, clutch slip speed of the drive is adjusted by manipulation of clutch pressure. This may be done in either closed loop mode or open loop mode by setting the clutch pressure to a predetermined value or continuously adjusting clutch pressure. Pressure is adjusted to produce a positively sloped function of sensed total torque of the clutch and turbine over the clutch slip speed. This produces extended service life of the drive train components, greater efficiency of the torque converter, and smoother operation of the drive.

Abstract: An aft heat shield for a fuel nozzle tip includes: an annular shield wall; an annular shield flange extending radially outward from an aft end of the shield wall; an annular baffle flange surrounding the conical section, and disposed such that an axial gap is defined between the shield flange and the baffle flange, the baffle flange including a radially outer rim extending axially forward therefrom; and a plurality of impingement cooling holes passing through the baffle flange and oriented to as to direct air flow towards the shield wall.

Abstract: A self-ready flash null Convention Logic (NCL) gate includes a one-shot circuit to create the flash timing to reset the gate to a null state. The one-shot circuit may be any type of circuit to generate a pulse in response to a change of state of an input line. In one embodiment, the one-shot circuit may start the pulse in response to a change of a flash input line and end the pulse in response to the NCL output being reset to a null state.

Abstract: An exemplary messaging anonymity system (MAS) for providing anonymous messaging between a mobile device and a third-party service provider via a communications network can include a processor, a network interface, and a memory. The memory can be configured to store instructions that, when executed, perform the steps of an exemplary method. The exemplary method can include receiving a mobile-originated (MO) message from a mobile device, the MO message being destined for a third-party service provider, determining to provision an anonymous subscriber identification (ASI) to be used in lieu of a subscriber address associated with the mobile device, provisioning the ASI, and sending the MO message to the third-party service provider, wherein the ASI is presented to the third-party service provider as an originating subscriber address.

Abstract: The invention relates to a device and method for using same for sanding a predetermined impression into a workpiece. The device has a pattern belt positioned inside the area formed by a sanding belt. A pad is positioned inside the area formed by the pattern belt. A raised pattern is formed on the outer surface of the pattern belt. In use, the pad is selectively controlled to contact the pattern belt, thereby urging the raised pattern of the pattern belt to contact the sanding belt. The portion of the sanding belt contacted by the pattern belt is urged toward the workpiece so that the predetermined impression is sanded into the workpiece.

Abstract: The invention relates to a device for sanding a predetermined impression into a workpiece. The device has a pattern belt positioned inside the area formed by a sanding belt. A pad is positioned inside the area formed by the pattern belt. A raised pattern is formed on the outer surface of the pattern belt. In use, the pad contacts the pattern belt, urging the raised pattern of the pattern belt to contact the sanding belt. The portion of the sanding belt contacted by the pattern belt is urged toward the workpiece so that the predetermined impression is sanded into the workpiece.

Abstract: Implementations described herein comprise knives and cutting systems for forming a predetermined impression into a wood layer and methods associated therewith. In some aspects a cutting system comprises at least one knife, and a means for rotating the wood block about a rotation axis. Each knife of the at least one knife can have a cutting portion and a base portion, wherein the cutting portion comprises a cutting surface defining a pattern. The at least one knife can be operatively positioned relative to the wood block such that, upon rotation of the wood block about the rotation axis, the peripheral surface of the wood block is urged against the cutting surface of the at least one knife to form the wood layer and the pattern defined on the cutting surface of the at least one knife is configured to form the predetermined impression into the wood layer.

Abstract: The invention relates to a device for sanding a predetermined impression into a workpiece. The device has a pattern belt positioned inside the area formed by a sanding belt. A pad is positioned inside the area formed by the pattern belt. A raised pattern is formed on the outer surface of the pattern belt. In use, the pad contacts the pattern belt, urging the raised pattern of the pattern belt to contact the sanding belt. The portion of the sanding belt contacted by the pattern belt is urged toward the workpiece so that the predetermined impression is sanded into the workpiece.

Abstract: An exemplary messaging anonymity system (MAS) for providing anonymous messaging between a mobile device and a third-party service provider via a communications network can include a processor, a network interface, and a memory. The memory can be configured to store instructions that, when executed, perform the steps of an exemplary method. The exemplary method can include receiving a mobile-originated (MO) message from a mobile device, the MO message being destined for a third-party service provider, determining to provision an anonymous subscriber identification (ASI) to be used in lieu of a subscriber address associated with the mobile device, provisioning the ASI, and sending the MO message to the third-party service provider, wherein the ASI is presented to the third-party service provider as an originating subscriber address.

Abstract: An exemplary messaging anonymity system (MAS) for providing anonymous messaging between a mobile device and a third-party service provider via a communications network can include a processor, a network interface, and a memory. The memory can be configured to store instructions that, when executed, perform the steps of an exemplary method. The exemplary method can include receiving a mobile-originated (MO) message from a mobile device, the MO message being destined for a third-party service provider, determining to provision an anonymous subscriber identification (ASI) to be used in lieu of a subscriber address associated with the mobile device, provisioning the ASI, and sending the MO message to the third-party service provider, wherein the ASI is presented to the third-party service provider as an originating subscriber address.