Abstract: Embodiments of the invention relate to a freestanding landscape waterfall assembly which reduces the weight of the waterfall as compared to conventional cast block waterfalls. In one embodiment, a freestanding landscape waterfall includes a face plate having an elongated aperture, a manifold having an outlet configured to direct water through the aperture, and an engagement feature configured to suspend the face plate such that the elongated aperture is in a horizontal orientation. In another embodiment, a freestanding landscape waterfall assembly includes a freestanding landscape waterfall, an overhead support system configured to suspend the freestanding landscape waterfall, and a catch basin positionable below the freestanding landscape waterfall.

Abstract: Embodiments of the present invention generally relate to a landscape waterfall. In one embodiment, a landscape waterfall includes an extruded frame structure and a catch basin disposed adjacent the frame structure. The landscape waterfall also includes a manifold having an outlet positioned to direct water into the catch basin and a pump system configured to pump water from the catch basin to the manifold. In another embodiment, a landscape waterfall includes a plastic extruded frame structure and a housing affixed to a front side of the extruded frame structure. The landscape waterfall also includes a catch basin disposed within the housing, a manifold coupled to the frame structure, and a pump system. In yet another embodiment, a landscape waterfall assembly kit includes a pump manifold, a plastic extruded back frame, a pump system, and packaging securing the pump manifold, the plastic extruded back frame, and the pump system.

Abstract: The present invention provides compositions and methods for investigating the structural basis of the activation process of CRAC channels, which are essential for T-lymphocyte activation and adaptive immunity. The invention also provides compositions and methods to design, identify and evaluate agents that modulate calcium signaling by regulating the interaction between STIM and Orai proteins. The invention also provides therapeutic agents for cases of immunological disorders, compromised immune function, organ transplantation, or thrombosis.

Abstract: An integrated circuit substrate having embedded lands with etching and plating control features provides improved manufacture of a high-density and low cost mounting and interconnect structure for integrated circuits. The integrated circuit substrate is formed by generating channels in a dielectric material, adding conductive material to fill the channels and then planarizing the conductive material, so that conductors are formed beneath the surface of the dielectric material. Lands are formed with feature shapes that reduce a dimpling effect at etching and/or an over-deposit of material during plating, both due to increased current density at the relatively larger land areas. Feature shapes may be a grid formed with line sizes similar to those employed to form conductive interconnects, so that all features on the substrate have essentially the same line width.

Abstract: The present invention relates to non contact, vision (imaging device/camera) guided, vision-enabled, solenoid valve liquid dispensing systems and methods of using same for automation of complex laboratory workflows and especially useful for a variety of biomedical and other applications including automated front-end sample preparation for matrix assisted laser desorption/ionization (MALDI) mass spectrometry analysis.

Abstract: An improved lighted rail system is provided in the present invention. In one embodiment, the lighted rail system includes a rail member having a plurality of spindle-receiving holes formed in a first side, at least one wire routed through the rail member; and a plurality of light elements coupled to the wire. In another embodiment, a rail member utilized in a lighted rail system includes an upper portion of a rail member having a conduit formed therein, a spindle-receiving portion configured to receive a spindle, a spindle stop formed in the rail member separating the conduit from the spindle-receiving portion, and a lighting system disposed in the rail member.

Abstract: The present invention provides a method and an apparatus for facilitating the creation and study of biological substrates. In particular, the present invention allows the location of materials deposited on a substrate to be identified, and communicated with great precision. This in turn allows additional biological materials to be deposited as probes over target locations. The present invention also allows for small regions of biological materials deposited on a substrate to be identified and repeatedly accessed, even when the biological substrate has been removed from the device originally used to review the region of interest and is then reinserted into the original device. Furthermore, the present invention allows a region of interest to be accurately located even using a machine that is different from the machine originally used to identify the region of interest.

Abstract: Systems, devices and methods are provided for viewing a pattern of biological material stained with dyes capable of absorbing, scattering or fluorescing light when illuminated by light emitting diodes (LEDs). The system includes a light source containing multiple light source arrays of different LED types emitting light at different wavelengths optimized for detecting specific dyes, a diffuser, a detector or viewer, and optional optical filters to ensure that the only light reaching the detector or viewer is light produced by fluorescence of the various dyes within a specific wavelength band. The optical filters are optional for detecting or viewing absorbance and light scatter. The different arrays of LED types can be selected in any combination during illumination and their intensity is adjustable over a range from 0-100%. A system and method is also provided for comparing patterns for two or more dyes contained in a single material.

Abstract: The present invention provides a method and an apparatus for facilitating the creation and study of biological substrates. In particular, the present invention allows the location of materials deposited on a substrate to be identified, and communicated with great precision. This in turn allows additional biological materials to be deposited as probes over target locations. The present invention also allows for small regions of biological materials deposited on a substrate to be identified and repeatedly accessed, even when the biological substrate has been removed from the device originally used to review the region of interest and is then reinserted into the original device. Furthermore, the present invention allows a region of interest to be accurately located even using a machine that is different from the machine originally used to identify the region of interest.