Patents by Inventor Richard Shimkets

Richard Shimkets has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20030224982
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 2, 2002
    Publication date: December 4, 2003
    Inventors: Li Li, Suresh G. Shenoy, Meera Patturajan, Karen Ellerman, Linda Gorman, Mei Zhong, Elina Catterton, Kimberly A. Spytek, Charles E. Miller, Shlomit R. Edinger, Tord Hjalt, Valerie Gerlach, Richard A. Shimkets, Raymond J. Taupier, David W. Anderson, Xiaojia (Sasha) Guo, Jason C. Baumgartner, Muralidhara Padigaru, John A. Peyman, Glennda Smithson, Stacie J. Casman, Edward Z. Voss, Ferenc L. Boldog, Carol E. A. Pena, Andrei Chapoval, Luca Rastelli, Ramesh Kekuda, Corine A.M. Vernet
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20030219823
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 6, 2002
    Publication date: November 27, 2003
    Inventors: John P. Alsobrook, Catherine E. Burgess, Shlomit R. Edinger, Valerie Gerlach, Denise M. Lepley, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Richard A. Shimkets, Kimberly A. Spytek, Raymond J. Taupier, Mei Zhong
  • Proteins and nucleic acids encoding same
    Publication number: 20030215449
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 15, 2002
    Publication date: November 20, 2003
    Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger, Edward Z. Voss, Charles E. Miller
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030216308
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: June 17, 2002
    Publication date: November 20, 2003
    Inventors: David W. Anderson, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, John L. Herrmann, Li Li, Peter S. Mezes, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Raymond J. Taupier, Corine A.M. Vernet
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030212257
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: April 2, 2002
    Publication date: November 13, 2003
    Inventors: Kimberly A. Spytek, Li Li, Shlomit R. Edinger, Karen Ellerman, David J. Stone, Uriel M. Malyankar, Richard A. Shimkets, Xiaojia Sasha Guo, David W. Anderson, Meera Patturajan, Constance Berghs, Valerie Gerlach, Vladimir Y. Gusev, Ramesh Kekuda, Linda Gorman, Bryan D. Zerhusen, Jason C. Baumgartner, Velizar T. Tchernev, Corine A.M. Vernet, Glennda Smithson, Suresh G. Shenoy, Xiaohong Liu, John R. MacDoughall
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030211485
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 29, 2002
    Publication date: November 13, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, David J. Stone, Glennda Smithson, Muralidhara Padigaru, Catherine Burgess, Corine Vernet, Elma Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan Zerhusen
  • Proteins and nucleic acids encoding same
    Publication number: 20030212256
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 16, 2001
    Publication date: November 13, 2003
    Inventors: Shlomit R. Edinger, Valerie Gerlach, John R. MacDougall, Uriel M. Malyankar, Glennda Smithson, Isabelle Millet, John A. Peyman, David J. Stone, Erik Gunther, Karen Ellerman, Richard A. Shimkets, Muralidhara Padigaru, Xiaojia Guo, Meera Patturajan, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Ramesh Kekuda, Kimberly A. Spytek, Esha A. Gangolli, Elma R. Fernandes, Linda Gorman
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030207800
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 13, 2001
    Publication date: November 6, 2003
    Inventors: Uriel M. Malyankar, Suresh G. Shenoy, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Xiaojia (Sasha) Guo, Ramesh Kekuda, Esha A. Gangolli, Richard A. Shimkets, Raymond J. Taupier, Li Li, Muralidhara Padigaru
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030207394
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 3, 2002
    Publication date: November 6, 2003
    Inventors: John P. Alsobrook, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, William M. Grosse, Vladimir Y. Gusev, Weizhen Ji, Denise M. Lepley, Xiaohong Liu, Amanda J. Mezick, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, Lei Shen, Suresh G. Shenoy, Richard A. Shimkets, Steven K. Spaderna, Kimberly A. Spytek, Edward S. Szekeres, Raymond J. Taupier, Velizar T. Tchernev, Bryan D. Zerhusen, Edward Z. Voss
  • Polypeptides and polynucleotides encoding same
    Publication number: 20030207348
    Abstract: The invention provides polypeptides, designated herein as SECP polypeptides, as well as polynucleotides encoding SECP polypeptides, and antibodies that immunospecifically-bind to SECP polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the SECP polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
    Type: Application
    Filed: February 13, 2002
    Publication date: November 6, 2003
    Inventors: Richard A. Shimkets, Elma R. Fernandes, Li Li, Linda Gorman, Vladimir Y. Gusev, Muralidhara Padigaru, Meera Patturajan, Suresh G. Shenoy, Kimberly A. Spytek
  • Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
    Publication number: 20030204052
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 4, 2001
    Publication date: October 30, 2003
    Inventors: John L. Herrmann, Luca Rastelli, Richard A. Shimkets
  • Proteins and nucleic acids encoding same
    Publication number: 20030203843
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: April 11, 2002
    Publication date: October 30, 2003
    Inventors: Carol E. A. Pena, Xiaojia (Sasha) Guo, Richard A. Shimkets, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Fuad Mehraban, James Newman Topper, Uriel M. Malyankar, Scott Michael Wasserman, Shlomit R. Edinger, Glennda Smithson, Erik Gunther, Laszlo Komuves
  • Novel amino acid sequences for human epidermal growth factor-like polypeptides
    Publication number: 20030199103
    Abstract: This application is drawn to novel amino acid sequences for mammalian polypeptides that have sequence similarity to a protein fragment of human epidermal growth factor. The polypeptides are novel secreted proteins of approximately 708 amino acids.
    Type: Application
    Filed: October 15, 2001
    Publication date: October 23, 2003
    Applicant: CuraGen Corporation
    Inventors: Richard A. Shimkets, Elma Fernandes, John Herrman, Corine Vernet
  • Proteins and nucleic acids encoding same
    Publication number: 20030198957
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: March 1, 2002
    Publication date: October 23, 2003
    Inventors: Ramesh Kekuda, Pamela B. Conley, Ruey-Bing Yang, Matthew Hart, James E. Tomlinson, James Newman Topper, Richard A. Shimkets, Martin D. Leach, Bryan D. Zerhusen, Laszlo Komuves, Muralidhara Padigaru
  • Noval human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030198958
    Abstract: The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
    Type: Application
    Filed: March 13, 2002
    Publication date: October 23, 2003
    Inventors: Richard A. Shimkets, Elma Fernandes, John L. Herrmann, Xiaohong Liu, Meijia Yang, Ferenc L. Boldog, Glennda Smithson, Luca Rastelli
  • Novel nucleic acid sequences encoding human fibroblast growth factor-like polypeptides
    Publication number: 20030194761
    Abstract: This application is drawn to novel nucleic acid sequences encoding mammalian polypeptides that have sequence similarity to human fibroblast growth factor, FGF-10. The nucleic acid sequence is 670 nucleotides long and contains an open reading frame from nucleotides 130 to 639. The encoded polypeptides are novel secreted proteins.
    Type: Application
    Filed: October 31, 2001
    Publication date: October 16, 2003
    Applicant: CuraGen Corporation
    Inventors: Richard A. Shimkets, Elma Fernandes, Ferenc Boldog
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030190715
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 12, 2001
    Publication date: October 9, 2003
    Inventors: William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Vishnu Mishra, Ramesh Kekuda, Li Li, Muralidhara Padigaru, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly A. Spytek, Shlomit R. Edinger, Valerie Gerlach, John R. MacDougall, Isabelle Millet, David J. Stone, Erik Gunther, Karen Ellerman
  • Novel hepatoma-derived growth factor-like proteins, polynucleotides encoding them and methods of use
    Publication number: 20030190708
    Abstract: The present invention provides HDGFX, a novel isolated polypeptide, as well as a polynucleotide encoding HDGFX and antibodies that immunospecifically bind to HDGFX or any derivative, variant, mutant, or fragment of the HDGFX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the HDGFX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: April 17, 2003
    Publication date: October 9, 2003
    Applicant: CuraGen Corporation
    Inventors: Catherine Burgess, Richard A. Shimkets, Corine Vernet, Ferenc L. Boldog, Meiji Yang, William J. La Rochelle, Stacey Minskoff
  • Novel fibroblast growth factor and nucleic acids encoding same
    Publication number: 20030186433
    Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.
    Type: Application
    Filed: June 17, 2002
    Publication date: October 2, 2003
    Inventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, William Grosse
  • Proteins and nucleic acids encoding same
    Publication number: 20030170630
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 21, 2001
    Publication date: September 11, 2003
    Inventors: John P. Alsobrook, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Denise M. Lepley, Catherine E. Burgess, Richard A. Shimkets, William M. Grosse, Edward S. Szekeres, Corine A.M. Vernet, Li Li, Stacie J. Casman, Ference L. Boldog, Linda Gorman, Esha A. Gangolli, Elma R. Fernandes, Danier K. Rieger, Shlomit R. Edinger, Erik Gunther, Isabelle Millet, Paul Sciore, Karen Ellerman, John R. MacDougall, Glennda Smithson