Patents by Inventor Richard Shimonkevitz

Richard Shimonkevitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20220288062
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: May 23, 2022
    Publication date: September 15, 2022
    Inventors: David BAR-OR, Raphael BAR-OR, Richard SHIMONKEVITZ
  • Treatment of T-cell mediated diseases
    Patent number: 11369598
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: June 28, 2022
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20210121457
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: October 1, 2020
    Publication date: April 29, 2021
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 10828296
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: November 10, 2020
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREAMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20200030321
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: October 2, 2019
    Publication date: January 30, 2020
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREAMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20180140598
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: July 6, 2017
    Publication date: May 24, 2018
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 9730924
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: August 15, 2017
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 9707227
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: July 18, 2017
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20160015705
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: March 3, 2015
    Publication date: January 21, 2016
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8969308
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: March 3, 2015
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8962568
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: February 24, 2015
    Assignee: Ampio Pharmaceuticals, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8551953
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: October 8, 2013
    Assignee: DMI Acquisition Corp.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8513196
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: August 20, 2013
    Assignee: DMI Acquisition Corp.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8324167
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: December 4, 2012
    Assignee: DMI Biosciences, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • Treatment of T-cell mediated diseases
    Patent number: 8183209
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Grant
    Filed: September 28, 2011
    Date of Patent: May 22, 2012
    Assignee: DMI Biosciences, Inc.
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20120022004
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: September 28, 2011
    Publication date: January 26, 2012
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20100190696
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20100143338
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 10, 2010
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz
  • TREATMENT OF T-CELL MEDIATED DISEASES
    Publication number: 20100144611
    Abstract: The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 10, 2010
    Inventors: David Bar-Or, Raphael Bar-Or, Richard Shimonkevitz