Abstract: The present invention relates to therapeutic dosing regimens utilizing a dose reduction strategy for treating disorders characterized by marked elevations of low density protein cholesterol (LDL-C) in the plasma of a patient. The subject therapeutic dosing regimens involve delivering as a single administration or plurality of administrations of an anti-proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist antibody as an initial dose of at least about 100 mg, and delivering as a single administration or plurality of administrations at a subsequent dose in an amount that is about the same as the initial dose, or at least half the initial dose after the patient has a LDL-C level at or below about 25, 20, 15 or 10 mg/dL, preferably at or below 10 mg/dL.

Abstract: Described is a system and method for defining a first time in a startup sequence of a computing system and determining first external resources that are available at the first time. A device driver then performs a first action based on the first external resources available at the first time. A second time in the startup sequence is defined and second external resources that are available at the second time are determined. The device driver then performs a second action based on the second external resources available at the second time.

Abstract: A foam controlling system uses electromagnetic energy to cut foam on the surface of a solution or liquid in a processing tank into at least two portions prior to the foam propagating and reaching the perimeter of the tank such that currents within the solution or liquid dissipate at least one of the foam portions. A purging fluid is provided to a laser head unit of the foam controlling system to reduce the dew point therein and thereby reduce or substantially eliminate undesirable condensation that could otherwise cause adverse optics contamination. Advantageously, the versatility and simplicity of the foam controlling system as well as its adaptability to various manufacturing formats makes the system an economical full plant solution.

Abstract: A radio frequency power amplifier has first and second amplifier transistors. The first and second amplifier transistors have a common element thereof electrically interconnected with a common bus. A forked conductor having two legs thereof electrically connected to the common bus, each leg having a distal end proximate one of the first and second amplifier transistors. The common bus and the forked conductor are generally symmetric about an axis about which the first and second amplifier transistors are symmetrically disposed.

Abstract: Methods of assembling a coupler are provided in which a first printed circuit board is provided, and a second printed circuit board is then surface mounted on the first printed circuit board. The first printed circuit board and the second printed circuit board are then electrically and mechanically connected to provide a coupler having a shielded region defined between the first printed circuit board and the second printed circuit board. The shielded region at least partly surrounds a coupler circuit disposed therein.

Abstract: A disposable beverage filter package comprises a flexible and permeable pouch having a sidewall extending downwardly from a top opening to a closed bottom. The pouch is suspended from and supported exclusively by an imperforate impermeable lid configured and arranged to close the top opening and to coact with the pouch in defining an enclosed chamber. A dry beverage medium is loosely contained within the chamber. The lid is piercable to admit a flow of heated liquid under pressure into the chamber, with the permeability of the pouch being such that the thus admitted liquid is retained temporarily in the chamber for infusion with the beverage medium before permeating through and flowing downwardly along the exterior of the sidewall as a liquid beverage.

Abstract: A surface mount technology (“SMT”) apparatus for use in routing radio frequencies (“RF”) between cavities that require a high level of isolation on a single printed circuit board (“PCB”). The SMT part is attached to the PCB over a stripline-ready trace which transitions to microstrip before and after the SMT stripline part to maintain consistent characteristic impedance. When presented with a high isolation need between two cavities using microstrip transmission lines, the proposed stripline SMT apparatus under the isolation wall will tend to provide the necessary isolation. The present invention provides a repeatable and reliable interconnect while improving the electrical match between the two cavities. Furthermore, the invention removes the costs associated with manually forming and soldering cables between PCBs.

Abstract: A cupholder for holding containers is provided with a number of container-holding cavities. Each of the container-holding cavities includes pairs of gripping flanges that extend inwardly toward centers of the cavities. The flanges include gripping points that extend toward each other and exert a gripping force along a bottom of an inserted container. The gripping flanges are pliable to accept a variety of inserted container sizes, but resilient enough to exert a container-holding force against containers inserted into the container-holding cavities.

Abstract: A radio frequency power amplifier has first and second amplifier transistors. The first and second amplifier transistors have a common element thereof electrically interconnected with a common bus. A forked conductor having two legs thereof electrically connected to the common bus, each leg having a distal end proximate one of the first and second amplifier transistors. The common bus and the forked conductor are generally symmetric about an axis about which the first and second amplifier transistors are symmetrically disposed.

Abstract: A beverage filter cartridge includes a cup-shaped outer container with a bottom and a side wall extending upwardly from the bottom wall to a circular rim surrounding an upper opening. The side wall has an upper section extending downwardly from the rim to an intermediate section, and a tapered lower section configured to provide a plurality of circumferentially spaced flutes extending downwardly from the intermediate section to the bottom wall. A filter element subdivides the interior of the container into first and second chambers. A beverage medium is stored in the first chamber. A cover is joined to the side wall at the rim to close the upper opening. The cover is yieldably piercable to accommodate an injection of liquid into the first chamber for combination with the beverage medium to produce a beverage.

Abstract: A surface mount technology (“SMT”) apparatus for use in routing radio frequencies (“RF”) between cavities that require a high level of isolation on a single printed circuit board (“PCB”). The SMT part is attached to the PCB over a stripline-ready trace which transitions to microstrip before and after the SMT stripline part to maintain consistent characteristic impedance. When presented with a high isolation need between two cavities using microstrip transmission lines, the proposed stripline SMT apparatus under the isolation wall will tend to provide the necessary isolation. The present invention provides a repeatable and reliable interconnect while improving the electrical match between the two cavities. Furthermore, the invention removes the costs associated with manually forming and soldering cables between PCBs.

Abstract: A beverage filter cartridge includes a cup-shaped outer container with a bottom and a side wall extending upwardly from the bottom wall to a circular rim surrounding an upper opening. The side wall has an upper section extending downwardly from the rim to an intermediate section, and a tapered lower section configured to provide a plurality of circumferentially spaced flutes extending downwardly from the intermediate section to the bottom wall. A filter element subdivides the interior of the container into first and second chambers. A beverage medium is stored in the first chamber. A cover is joined to the side wall at the rim to close the upper opening. The cover is yieldably piercable to accommodate an injection of liquid into the first chamber for combination with the beverage medium to produce a beverage.

Abstract: A door guard for protecting a door assembly including a door frame and moldings positioned about a door. Guide channels are provided on the base of the door guard for receiving tightening straps to secure the door guard to the door assembly. Raised ridges are provided on the outer side panels of the door guard to receive the tightening straps and communicate tightening pressure to the door guard. A raised block is provided on an inside surface of the door guard to maintain separation of the moldings in response to the tightening pressure. A pad is provided on an outside surface of the door guard to cushion the end of the door assembly.