Patents by Inventor Richard T. Sayre

Richard T. Sayre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946059
    Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoids in plant cell suspension cultures.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: April 2, 2024
    Assignee: TRAIT BIOSCIENCES, INC.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga, Stephanie Willette
  • Patent number: 11905543
    Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble acetylated cannabinoid glycosides in plant cell suspension cultures.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: February 20, 2024
    Assignee: TRAIT BIOSCEINCES, INC.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga, Stephanie Willette
  • Patent number: 11773402
    Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in stably transformed whole plant, or a cell suspension culture system.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: October 3, 2023
    Assignee: TRAIT BIOSCIENCES INC.
    Inventors: Richard T. Sayre, Elton Carvalho Goncalves, Tawanda Zidenga
  • Publication number: 20230047351
    Abstract: The inventive technology relates to novel paratransgenic strategies for the biocontrol of pathogens in animal systems using interfering RNA molecules expressed in genetically modified bacteria that may be configured to colonize a target host. In one preferred embodiment, the invention includes novel paratransgenic strategies for the biocontrol of pathogens in aquatic organisms raised in aquaculture environments.
    Type: Application
    Filed: September 13, 2022
    Publication date: February 16, 2023
    Inventors: Richard T. Sayre, Tatiana Vinogradova-Shah, Elena Sineva
  • Patent number: 11466281
    Abstract: The present invention includes systems, methods and compositions for the generation of water-soluble cannabinoids in yeast, and other plant cell suspension cultures as well as novel water-soluble cannabinoid compounds. The present invention also includes compositions of matter that may contain one or more water-soluble cannabinoids.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: October 11, 2022
    Assignee: TRAIT BIOSCIENCES INC.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga
  • Patent number: 11446339
    Abstract: The inventive technology relates to novel paratransgenic strategies for the biocontrol of pathogens in animal systems using interfering RNA molecules expressed in genetically modified bacteria that may be configured to colonize a target host. In one preferred embodiment, the invention includes novel paratransgenic strategies for the biocontrol of pathogens in aquatic organisms raised in aquaculture environments.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: September 20, 2022
    Assignee: PEBBLE LABS INC.
    Inventors: Richard T. Sayre, Tatiana Vinogradova-Shah, Elena Sineva
  • Patent number: 11447788
    Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: September 20, 2022
    Assignee: TRAIT BIOSCEINCES, INC.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga
  • Publication number: 20220267820
    Abstract: The present invention relates generally to the use of novel UDP-glucosyltransferases enzymes having specific activity towards cannabinoid compounds. The present invention further relates generally to the use of novel UGT enzymes having specific activity towards cannabinoid compounds to generate water-soluble cannabinoid glycoside compounds.
    Type: Application
    Filed: March 1, 2021
    Publication date: August 25, 2022
    Inventors: Richard T. Sayre, Elton Carvalho Goncalves, Tawanda Zidenga, Stephanie Willette, Timothy Travers, Erick Lebrun
  • Patent number: 11352634
    Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: June 7, 2022
    Assignee: Trait Biosciences, Inc.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga
  • Patent number: 11339400
    Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: May 24, 2022
    Assignee: Trait Biosciences, Inc.
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga
  • Publication number: 20220151977
    Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis. In particular, the inventive technology includes novel systems, methods, and compositions to solubilize short-chain fatty acid phenolic coin-pounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein such as: lipocalins, lipocalin-like, odorant-binding proteins, and odorant-binding-like proteins.
    Type: Application
    Filed: February 4, 2020
    Publication date: May 19, 2022
    Inventors: Jennifer Stamps, Elton Carvalho Goncalves, Richard T. Sayre, Tawanda Zidenga, Erick Scott LeBrun, Timothy Travers
  • Publication number: 20220152212
    Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis and other cannabinoid producing plants. In particular, the inventive technology includes novel systems and methods to solubilize short-chain fatty acid phenolic compounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein.
    Type: Application
    Filed: February 4, 2020
    Publication date: May 19, 2022
    Inventors: Jennifer Stamps, Elton Carvalho Goncalves, Richard T. Sayre, Tawanda Zidenga, Erick Scott LeBrun, Timothy Travers
  • Publication number: 20210348204
    Abstract: The current inventive technology includes novel systems, methods and compositions for the in vivo production, modification and isolation of terpene compounds from Cannabis or other plants. In particular, the invention provides systems and methods for high level in vivo biosynthesis of water-soluble terpene compounds. In one preferred embodiment, the present invention generally relates to the conversion of Cannabis sativa or hemp derived terpenes into water-soluble terpene compounds, such as terpene glycosides, glycosylated-xylosylated terpenes, and an acetylated glycoside terpenes. In one preferred aspect, the invention may include system for producing water-soluble terpene compounds in yeast and tobacco cell suspension cultures, as well as an in planta system using transgenic Cannabis or hemp plants.
    Type: Application
    Filed: October 16, 2019
    Publication date: November 11, 2021
    Inventors: Richard T. Sayre, Elton Carvalho Goncalves, Jennifer Stamps, Tawanda Zidenga, Stephanie Willette
  • Publication number: 20210024948
    Abstract: The invention include systems, methods, and compositions related to the enhancement of photosynthetic electron transfer rates, abiotic stress tolerance, CO2 fixation rates, and increases in yield/biomass in plants. These methods and associated transgenic plants encompass the expression, or overexpression, of one or more genes that improve photosynthetic electron transfer rates, abiotic stress tolerance, CO2 fixation rates, and yield/biomass in plants. Such enhanced plant characteristics may be achieved through the expression, or overexpression of select photosynthetic ferredoxin proteins in a plant or plant cell. In certain embodiments, such enhanced plant characteristics may be achieved through the expression, or overexpression, of one or more photosynthetic ferredoxin proteins from a C4 plant in a C3 plant or plant cell.
    Type: Application
    Filed: March 28, 2019
    Publication date: January 28, 2021
    Inventors: Richard T. Sayre, Panagiotis Lymperopoulos, Choon-Hwan Lee, Guangxi Wu
  • Publication number: 20200405782
    Abstract: The inventive technology relates to novel paratransgenic strategies for the biocontrol of pathogens in animal systems using interfering RNA molecules expressed in genetically modified bacteria that may be configured to colonize a target host. In one preferred embodiment, the invention includes novel paratransgenic strategies for the biocontrol of pathogens in aquatic organisms raised in aquaculture environments.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: Richard T. Sayre, Tatiana Vinogradova-Shah, Elena Sineva
  • Patent number: 10774329
    Abstract: The inventive technology relates to novel paratransgenic strategies for the biocontrol of pathogens in animal systems using interfering RNA molecules expressed in genetically modified bacteria that may be configured to colonize a target host. In one preferred embodiment, the invention includes novel paratransgenic strategies for the biocontrol of pathogens in aquatic organisms raised in aquaculture environments.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: September 15, 2020
    Assignee: PEBBLE LABS USA INC.
    Inventors: Richard T. Sayre, Tatiana Vinogradova-Shah
  • Publication number: 20200046639
    Abstract: The present invention includes systems, methods and compositions related to the production and use of chemically modified cannabinoid food and beverage additives having enhanced water solubility and stability.
    Type: Application
    Filed: May 29, 2019
    Publication date: February 13, 2020
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga, Stephanie Willette
  • Publication number: 20200032267
    Abstract: The inventive technology relates to novel paratransgenic strategies for the biocontrol of pathogens in animal systems using interfering RNA molecules expressed in genetically modified bacteria that may be configured to colonize a target host. In one preferred embodiment, the invention includes novel paratransgenic strategies for the biocontrol of pathogens in aquatic organisms raised in aquaculture environments.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 30, 2020
    Inventors: Richard T. Sayre, Tatiana Vinogradova-Shah
  • Publication number: 20190382807
    Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble acetylated cannabinoid glycosides in plant cell suspension cultures.
    Type: Application
    Filed: May 29, 2019
    Publication date: December 19, 2019
    Inventors: Richard T. Sayre, Elton Carvalho Gonçalves, Tawanda Zidenga, Stephanie Willette
  • Publication number: 20190338301
    Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in stably transformed whole plant, or a cell suspension culture system.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 7, 2019
    Inventors: RICHARD T. SAYRE, ELTON CARVALHO GONCALVES, TAWANDA ZIDENGA