Abstract: A method of operating a material reduction or separating machine includes operating the machine with power from a power system to produce an outlet stream of material. The volume of the outlet stream of material is monitored, as is consumption of the power system from the operation of the material reduction or separating machine. With an on-board controller of the material reduction or separating machine a productivity measure is calculated as a unit volume per unit consumption. The productivity measure is displayed on an operator's display during the operation of the material reduction or separating machine to produce the outlet stream of material.

Abstract: A haul truck can include a frame, a traction system for moving the frame, an access platform coupled to the frame, a truck bed having a canopy extending over the access platform, an antenna support structure arranged on the access platform, the antenna support structure extending upward to support a GNSS receiver positioned proximate a front of the canopy, and a non-metallic protective barrier coupled to the canopy and positioned towards the front of the canopy and positioned to deflect objects from striking the GNSS receiver.

Abstract: It is advantageous for the dump body of a mining or off-road truck to be both strong and lightweight. Accordingly, a dump body with a faceted floor is disclosed. The dump body comprises a floor formed from a plurality of planar plates, arranged in two dimensions, and joined at angles to form a pseudo-curvature. The planar plates are easy and inexpensive to manufacture, and the angled joints provide rigidity that eliminates the need for external stiffeners, thereby maintaining the strength of the dump body while decreasing the weight and cost of the dump body.

Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus (“PEDV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PEDV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full length PEDV genomes that can replicate efficiently in host animals and tissue culture.

Abstract: An underground utility locator is provided. The underground utility locator includes a wand, a GNSS module, a power module, a smoothing circuit, and a multi-layer enclosure. The wand has a top end and a bottom end and includes at least one antenna configured to output a field strength signal in response to an electromagnetic field. The GNSS module is coupled to the top end of the wand. The power module is coupled to the wand. The multi-layer enclosure at least partially surrounds the GNSS module and includes an outer shell layer and an inner shell layer. The outer shell layer and the inner shell layer are partially separated by an air gap.

Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus (“PEDV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PEDV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full length PEDV genomes that can replicate efficiently in host animals and tissue culture.

Abstract: Deposition of calcium-containing minerals such as hydroxyapatite and whitlockite in the subretinal pigment epithelial (sub-RPE) space is linked to the development of, and progression to, end-stage age-related macular degeneration (AMD). Calcification in the sub-RPE space is also directly linked to other diseases such as Pseudoxanthoma elasticum (PXE). These deposits bind to tetracycline derivatives and can be imaged by fluorescence lifetime contrast using multiphoton (infrared) excitation.

Abstract: This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.

Abstract: Embodiments include an end effector including an anvil that includes a first end, a second end, and an anvil face positionable on the first side of an anatomical structure, a cartridge operably configured to house a plurality of staples, the cartridge comprising a first end, a second end, and a cartridge face positionable on the second side of the anatomical structure. The end effector includes a blade assembly comprising a blade, a beam, and a nut, the blade comprising a first side and a second side joined at a cutting edge. The end effector includes first and second electrodes coupled to the first side of the blade and an electrosurgical power generating source in electrical communication with the first and second electrodes.

Abstract: Embodiments include an end effector including an anvil that includes a first end, a second end, and an anvil face positionable on the first side of an anatomical structure, a cartridge operably configured to house a plurality of staples, the cartridge comprising a first end, a second end, and a cartridge face positionable on the second side of the anatomical structure. The end effector includes a blade assembly comprising a blade, a beam, and a nut, the blade comprising a first side and a second side joined at a cutting edge. The end effector includes first and second electrodes coupled to the first side of the blade and an electrosurgical power generating source in electrical communication with the first and second electrodes.

Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus (“PEDV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PEDV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full length PEDV genomes that can replicate efficiently in host animals and tissue culture.

Abstract: A hand held spray dispenser in which air and liquid are pressurised towards a mixing chamber by energy generated by a manual activation element that is rotated with a unidirectional twist to energise one or more energy storage bodies, energy from which is released to generate sufficient air pressure and air flow and sufficient liquid flow for a spray to be formed from the air-liquid mixture.

Abstract: This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.

Abstract: A request from a client device is received at a first one of a plurality of compute nodes at a first one of a plurality of data centers of a distributed cloud computing network. A destination of the request is determined. An optimized route for transmitting the request toward an origin server that corresponds with the destination of the request is determined, where the optimized route is based on at least in part on probe data between data centers of the distributed cloud computing network for a plurality of transit connections, and where the optimized route has an IP address that encodes an identification of which of the plurality of transit connections is to be used to deliver the request. The request is transmitted to a next hop as defined by the optimized route over the identified one of the plurality of transit connections.

Abstract: A hand held spray dispenser in which air and liquid are pressurised towards a turbulence chamber and wherein air is introduced into the liquid adjacent to an inlet orifice of the turbulence chamber and the mixture passes through the inlet orifice into the turbulence chamber before being expelled through an exit orifice.

Abstract: Embodiments include an end effector including an anvil that includes a first end, a second end, and an anvil face positionable on the first side of an anatomical structure, a cartridge operably configured to house a plurality of staples, the cartridge comprising a first end, a second end, and a cartridge face positionable on the second side of the anatomical structure. The end effector includes a blade assembly comprising a blade, a beam, and a nut, the blade comprising a first side and a second side joined at a cutting edge. The end effector includes first and second electrodes coupled to the first side of the blade and an electrosurgical power generating source in electrical communication with the first and second electrodes.

Abstract: A request from a client device is received at a first one of a plurality of compute nodes at a first one of a plurality of data centers of a distributed cloud computing network. A destination of the request is determined. An optimized route for transmitting the request toward an origin server that corresponds with the destination of the request is determined, where the optimized route is based on at least in part on probe data between data centers of the distributed cloud computing network for a plurality of transit connections, and where the optimized route has an IP address that encodes an identification of which of the plurality of transit connections is to be used to deliver the request. The request is transmitted to a next hop as defined by the optimized route over the identified one of the plurality of transit connections.

Abstract: A request from a client device is received at a first one of a plurality of compute nodes at a first one of a plurality of data centers of a distributed cloud computing network. A destination of the request is determined. An optimized route for transmitting the request toward an origin server that corresponds with the destination of the request is determined, where the optimized route is based on at least in part on probe data between data centers of the distributed cloud computing network for a plurality of transit connections, and where the optimized route has an IP address that encodes an identification of which of the plurality of transit connections is to be used to deliver the request. The request is transmitted to a next hop as defined by the optimized route over the identified one of the plurality of transit connections.

Abstract: A game-hosting service of a service provider network is configured to place game sessions on fleets of virtual machine (VM) instances using a value-based approach. In order to place a game session on a fleet, the game-hosting service may determine one or more attributes of the game session request, such as player attributes and/or game attributes. The game-hosting service may also determine available fleets of VM instances allocated to a subscriber associated with the game session request, which may be located across disparate geographical regions. A value(s) may be determined based on the attributes of the game session request, and the value(s) may be used to select a fleet of the available fleets for hosting the game session.

Abstract: A multi-region game server fleet may span a plurality of computing regions including a home computing region and one or more remote computing regions. A fleet management service operating in the home computing region may receive a request to perform a modification to the multi-region game server fleet, such as adding an additional remote computing region, removing an existing remote computing region, or making a configuration change. The modification may be performed, at least in part, by one or more region specific worker processes hosted in the home region. The fleet management service operating in the home computing region may also receive a request to perform an interaction with a specific remote region game server. An instruction corresponding to the interaction may be transmitted, by a region-specific computing function hosted in the home region, to the specific remote region game server.