Abstract: Provided are modified arginine deiminase (ADI) proteins, including ADI proteins that comprise one or more substitutions which increase expression in bacteria as insoluble and refoldable inclusion bodies. Also provided are methods of producing the modified ADI proteins, compositions comprising the ADI proteins, and related methods of treating arginine-dependent and related diseases such as cancer.

Abstract: A mounting device for an elongate member, comprising: an elongate housing having an elongate axis; an internal passageway passing through the elongate housing parallel to the elongate axis; an elongate sleeve located within the internal passageway and being configured for longitudinal movement along the passageway; a plurality of ball-receiving recesses in the wall of the internal passageway, each recess having a ball-guiding surface inclined to the longitudinal axis; a plurality of apertures in the sleeve; a ball located in each of the ball-receiving recesses and engaged with a respective aperture in the sleeve, the balls and the apertures being configured to allow the balls to project partially through the apertures but to prevent balls from passing through; biasing means configured to bias the sleeve in a direction to urge the balls to project radially inwardly through their respective apertures in the sleeve and into the internal passageway.

Abstract: A mounting device (110) for an elongate flexible member extending through an aperture (102), comprising: an elongate body (130) having a longitudinal axis; an internal passageway passing through the elongate body (130) parallel to the longitudinal axis, for receipt of the elongate flexible member; a plurality of apertures (132) in the elongate body (130); an engagement member (136) in each apertures (132) and constrained to move along a displacement axis inclined to the longitudinal axis of the elongate body (130); a plurality of actuation members (142), each engaged with a respective engagement member (136), whereby displacement of the actuation member (142) in a first direction displaces the engagement members (136) outwardly to project beyond the periphery of the elongate body (130) and displacement of the actuations members (142) in a second, opposite direction displaces the engagement members (136) inwardly; and biasing means (182) biasing the actuation members (142) in the first direction.

Abstract: A mounting device (110) for an elongate flexible member extending through an aperture (102), comprising: an elongate body (130) having a longitudinal axis; an internal passageway passing through the elongate body (130) parallel to the longitudinal axis, for receipt of the elongate flexible member; a plurality of apertures (132) in the elongate body (130); an engagement member (136) in each apertures (132) and constrained to move along a displacement axis inclined to the longitudinal axis of the elongate body (130); a plurality of actuation members (142), each engaged with a respective engagement member (136), whereby displacement of the actuation member (142) in a first direction displaces the engagement members (136) outwardly to project beyond the periphery of the elongate body (130) and displacement of the actuations members (142) in a second, opposite direction displaces the engagement members (136) inwardly; and biasing means (182) biasing the actuation members (142) in the first direction.

Abstract: An apparatus and method are provided for implementing one or more security services to messages and data being communicated between a first network and a second network. In particular, a network bridge device is provided for applying communications security services to data passing by means of the device from a first network to a second network, the device having a first network interface for linking to the first network, a second network interface for linking to the second network, and a unidirectional link between the first and second network interfaces within the device incorporating a first hardware logic module, configured to apply one or more predetermined data security functions to message data received via the first network interface, and a second hardware logic module, arranged to apply a predetermined scheme for authentication of the source of messages passing through the device.

Abstract: Mounting devices for an elongate flexible member, such as an electrical cable passing through the wall of a structure, are described. The mounting devices may include an elongate body having a longitudinal axis and elongate recesses that are inclined with respect to the longitudinal axis. An internal passageway for the elongate flexible member may pass through the elongate body parallel to the longitudinal axis, and apertures corresponding to the recesses may be disposed in the outer peripheral face of the elongate body. An engagement member, such as a ball, may be mounted in each recess and move along the recess. The engagement members, recesses and the apertures may be dimensioned to allow the engagement members to project partially beyond the outer peripheral face of the elongate body but to prevent the engagement members from leaving the recesses through the apertures in the outer peripheral face of the elongate body.

Abstract: An integrated, automated method to make various abdominal aortic stents with 3D printing technology and computerized recognition algorithms. Cost, risk, and time from assessment to recovery are reduced.

Abstract: Mounting devices for an elongate flexible member, such as an electrical cable passing through the wall of a structure, are described. The mounting devices may include an elongate body having a longitudinal axis and elongate recesses that are inclined with respect to the longitudinal axis. An internal passageway for the elongate flexible member may pass through the elongate body parallel to the longitudinal axis, and apertures corresponding to the recesses may be disposed in the outer peripheral face of the elongate body. An engagement member, such as a ball, may be mounted in each recess and move along the recess. The engagement members, recesses and the apertures may be dimensioned to allow the engagement members to project partially beyond the outer peripheral face of the elongate body but to prevent the engagement members from leaving the recesses through the apertures in the outer peripheral face of the elongate body.

Abstract: A magnetic circuit (400) comprises a magnetic path which includes at least one magnetic source (102) arranged to generate magnetic flux within the magnetic path. A magnetic flux-concentrating element 402 is magnetically coupled to the magnetic source, and arranged to concentrate magnetic-flux generated by the magnetic source within a volume adjacent to the magnetic flux-concentrating element (402). Some embodiments of the magnetic circuit (400) comprise at least first (102) and second (104) magnetic sources, which may advantageously be arranged to generate magnetic flux in a common direction within the magnetic path.

Abstract: An apparatus and method are provided for implementing one or more security services to messages and data being communicated between a first network and a second network. In particular, a network bridge device is provided for applying communications security services to data passing by means of the device from a first network to a second network, the device having a first network interface for linking to the first network, a second network interface for linking to the second network, and a unidirectional link between the first and second network interfaces within the device incorporating a first hardware logic module, configured to apply one or more predetermined data security functions to message data received via the first network interface, and a second hardware logic module, arranged to apply a predetermined scheme for authentication of the source of messages passing through the device.

Abstract: A business process management system may include a parent workflow process and a child workflow process. The parent workflow process may include a call to the child workflow process. The business process management system may also include a workflow engine that is configured to execute the parent workflow process and the child workflow process, and that is configured to determine an undefined characteristic of the child workflow process with reference to data that corresponds to the parent workflow process.

Abstract: A system (1321) for accessing an image album comprising a plurality of source images over a network (1305) is disclosed. A representation of the image album is stored on a server (1301). The system (1321) comprises means (1304) for downloading, from the server (1301), the representation of the image album. The means (1304) accesses a reduced resolution version of a said one of the plurality of source images dependent upon the representation of the album, and retrieves, from a storage device (eg 1302) located remotely from the server (1301), the source image corresponding to the reduced resolution version.

Abstract: A system (1321) for accessing an image album comprising a plurality of source images over a network (1305) is disclosed. A representation of the image album is stored on a server (1301). The system (1321) comprises means (1304) for downloading, from the server (1301), the representation of the image album. The means (1304) accesses a reduced resolution version of a said one of the plurality of source images dependent upon the representation of the album, and retrieves, from a storage device (eg 1302) located remotely from the server (1301), the source image corresponding to the reduced resolution version.