Patents by Inventor Richard Tizard

Richard Tizard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHODS FOR THE DETECTION OF CRIPTO-3
    Publication number: 20100041032
    Abstract: The present invention is based, at least in part, on the discovery that the pseudogene TDGF3 (Cripto-3) is expressed in cells and, in particular, that TDGF3 overexpression is associated with transformation of a cell, e.g., TDGF3 is overexpressed in cancer cell lines and cells from tumor tissue. Accordingly, the invention provides compositions, kits, and methods for detecting the presence of a TDGF3 polynucleotide or polypeptide in a sample. The invention further provides compositions, kits and methods for assessing whether a cell is transformed as well as for assessing whether a patient is a suitable candidate for an anti-Cripto antibody therapy.
    Type: Application
    Filed: April 30, 2007
    Publication date: February 18, 2010
    Applicant: Biogen Idec MA Inc.
    Inventors: Olivia Orozco, Michele Sanicola-Nadel, Eugene Choi, John Carulli, Richard Tizard, Suzanne Szak, Chao Sun
  • Renal Regulatory Elements and Methods of Use Thereof
    Publication number: 20070130629
    Abstract: Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.
    Type: Application
    Filed: January 17, 2007
    Publication date: June 7, 2007
    Applicants: Biogen Idec MA Inc., The General Hospital Corporation
    Inventors: Michele Sanicola-Nadel, Catherine Hession, Richard Tizard, Joseph Bonventre
  • Renal regulatory elements and methods of use thereof
    Patent number: 7179901
    Abstract: Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: February 20, 2007
    Assignees: Biogen Idec MA Inc., The General Hospital Corporation
    Inventors: Michele Sanicola-Nadel, Catherine Hession, Richard Tizard, Jr., Joseph Bonventre
  • Renal regulatory elements and methods of use thereof
    Publication number: 20030215831
    Abstract: Disclosed are cis-acting regulatory elements from a KIM-1 gene. The elements can be used to direct the expression of operably linked sequences in renal tissue.
    Type: Application
    Filed: March 28, 2003
    Publication date: November 20, 2003
    Inventors: Michele Sanicola- Nadel, Catherine Hession, Richard Tizard, Joseph Bonventre
  • DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3
    Patent number: 4956281
    Abstract: Polypeptides that bind to CD2, the receptor on the surface of T-lymphocytes. Most preferably, the polypeptides bind to CD2 on the surface of T-lymphocytes and inhibit adhesion between T-lymphocytes and target cells. DNA sequences that code on expression in appropriate unicellular hosts for those polypeptides. Methods of making and using those polypeptides in therapy and diagnosis.
    Type: Grant
    Filed: June 3, 1987
    Date of Patent: September 11, 1990
    Assignees: Biogen, Inc., Dana Farber Cancer Institute, Inc.
    Inventors: Barbara P. Wallner, Timothy A. Springer, Catherine Hession, Richard Tizard, Robert Mattaliano, Michael L. Dustin