Abstract: This invention generally relates to stents, such as intravascular stents. More particularly, the invention is directed to stents comprising expandable stent segments, such as unconnected expandable stent segments. The invention is also directed to methods for making such stents.

Abstract: A medical device coated with carrier macromolecules, wherein the carrier macromolecules are conjugated with a therapeutic agent. The carrier macromolecules may be antibodies which bind the therapeutic agent at the antigen binding site or by covalent bonding. The carrier macromolecules may be tethered to the surface of or dispersed within a coating on the medical device. The carrier macromolecules may release the therapeutic agent upon exposure to a trigger, which may be exposure to an aqueous environment, or a change in the pH or the ionic strength of the environment. The carrier macromolecules may also be bispecific antibodies directed to both a therapeutic agent and a target antigen. In some cases, binding of the target antigen causes the therapeutic agent to be released from the bispecific antibody. Also provided are methods of controlling the release and targeting of therapeutic agents eluted from a medical device.

Abstract: A stent formed of a plurality of serpentine bands, each band formed from a plurality of straight sections connected by curved end portions, at least some of the end portions having a curable resin composition disposed thereon, and a method of making and using the same.

Abstract: A stent assembly comprises a second stent body and a substantially tubular first stent body defining a first lumen and containing a side branch opening. In an undeployed state, the second stent body is at least partially comprised of rings having peaks and spans between these peaks. In a deployed state, the rings of the second stent body define a second lumen opening in fluid communication with the first lumen. The second lumen is capable of having tapering strength and geometry and can extend and form an oblique angle relative to the longitudinal axis of the first stent body.

Abstract: A stent may comprise a plurality of serpentine bands connected by connector struts. The stent may further comprise a side branch cell having a plurality of outwardly deployable petals. Each serpentine band may have an approximate longitudinal axis. A portion of the serpentine bands may be flared in the unexpanded state, wherein a portion of the axis of each flared band is oriented helically about a portion of the stent. The bands may reorient during stent expansion, whereafter the axis of each band is oriented in a circumferential direction.

Abstract: A stent has an undeployed state and a deployed state. The stent has a primary body with an outer surface and an inner surface with a wall extending therebetween. The inner surface defines a first lumen having a first longitudinal axis therethrough. The primary body has at least two side branch portions which define secondary lumens having a second longitudinal axis therethrough. The first lumen and the secondary lumen are in fluid communication and in the deployed state one of the side branch portions deploy and the second longitudinal axis forms an oblique angle with the first longitudinal axis.

Abstract: A stent assembly comprises a second stent body and a substantially tubular first stent body defining a first lumen and containing a side branch opening. In an undeployed state, the second stent body is at least partially comprised of rings having peaks and valleys at least some of the valleys of adjacent rings being interconnected by bridges. In an expanded state, the rings of the second stent body define a second lumen opening in fluid communication with the first lumen. The second lumen has superior body vessel coverage and is flexible enough to form an oblique angle relative to the longitudinal axis of the first stent body.

Abstract: A stent assembly comprises a proximal stent and a distal stent. Each stent has a tubular body defining a stent lumen and a circumference. A proximal flap extends from the distal end of the proximal stent and a distal flap extends from the proximal end of the distal stent. Each flap defines only a portion of the circumference. In an expanded state the proximal flap and the distal flap form a side branch support having a side branch support lumen. The side branch support lumen is in fluid communication with the stent lumen and has a longitudinal axis different from that of the stent lumen.