Patents by Inventor Richard Torres

Richard Torres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200371033
    Abstract: The invention provides improved systems and methods for multiphoton microscopy including pixel clocking techniques for minimizing pixel integration time and providing consistent signal intensity with maximized imaging speeds. Various systems and method are described for optimizing laser repetition rate based on dye lifetime, combining polygonal mirror scanning and stage translation, using the laser pulse signal to time pixel collection, and minimizing laser pulses and dye usage based on signal to background ratios.
    Type: Application
    Filed: June 8, 2020
    Publication date: November 26, 2020
    Inventors: Michael Levene, Richard Torres
  • Publication number: 20200348216
    Abstract: The present invention relates to systems and methods for tissue processing and analysis. Tissue chambers are configured to allow single-container chemical processing, imaging, and wax embedding of tissue samples in a single container without manipulation between steps. Tissue chambers with features to support the tissue sample and allow fluid flow between the tissue sample and the tissue chamber surface are disclosed. The features may be index matched to sample structures of interest or dissolvable in clearing solution to allow for in-chamber imaging with minimal distortion. Specialized tissue processing and wax removal apparatuses are also disclosed including for use with tissue chambers having frangible portions to permit ease of wax removal.
    Type: Application
    Filed: January 6, 2020
    Publication date: November 5, 2020
    Inventors: Michael Levene, Richard Torres
  • Publication number: 20200339672
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Application
    Filed: July 10, 2020
    Publication date: October 29, 2020
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Lynn MACDONALD, Richard TORRES, Marc R. MORRA, Joel H. MARTIN, Joel C. REINHARDT, Paul TISEO
  • Patent number: 10745471
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: August 18, 2020
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Lynn MacDonald, Richard Torres, Marc R. Morra, Joel H. Martin, Joel C. Reinhardt, Paul Tiseo
  • Publication number: 20200225758
    Abstract: A method for augmenting a two-stage hand gesture input comprises receiving hand tracking data for a hand of a user. A gesture recognition machine recognizes that the user has performed a first-stage gesture based on one or more parameters derived from the received hand tracking data satisfying first-stage gesture criteria. An affordance cueing a second-stage gesture is provided to the user responsive to recognizing the first-stage gesture. The gesture recognition machine recognizes that the user has performed the second-stage gesture based on one or more parameters derived from the received hand tracking data satisfying second-stage gesture criteria. A graphical user interface element is displayed responsive to recognizing the second-stage gesture.
    Type: Application
    Filed: March 26, 2019
    Publication date: July 16, 2020
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Sheng Kai TANG, Julia SCHWARZ, Thomas Matthew GABLE, Casey Leon MEEKHOF, Chuan QIN, Nahil Tawfik SHARKASI, Nicholas Ferianc KAMUDA, Ramiro S. TORRES, Joshua Kyle NEFF, Jamie Bryant KIRSCHENBAUM, Neil Richard KRONLAGE
  • Patent number: 10677730
    Abstract: The invention provides improved systems and methods for multiphoton microscopy including pixel clocking techniques for minimizing pixel integration time and providing consistent signal intensity with maximized imaging speeds. Various systems and method are described for optimizing laser repetition rate based on dye lifetime, combining polygonal mirror scanning and stage translation, using the laser pulse signal to time pixel collection, and minimizing laser pulses and dye usage based on signal to background ratios.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: June 9, 2020
    Assignee: APLLIKATE TECHNOLOGIES LLC
    Inventors: Michael Levene, Richard Torres
  • Patent number: 10654976
    Abstract: A method for producing a cross-linked siloxane network comprises the steps of: (a) providing a first part comprising (i) a first siloxane compound comprising at least one cyclic siloxane moiety and (ii) a second siloxane compound comprising a plurality of siloxane moieties, (b) providing a second part, the second part comprising a hydroxide salt, (c) combining the first part and the second part to produce a reaction mixture, (d) heating the reaction mixture to a temperature sufficient for the hydroxide salt to open the ring of the cyclic siloxane moiety, and (e) maintaining the reaction mixture at an elevated temperature so that at least a portion of the opened cyclic siloxane moieties react to produce a cross-linked siloxane network.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: May 19, 2020
    Assignee: Milliken & Company
    Inventors: Yunzhang Wang, Xinfei Yu, Russell A. Stapleton, Michael E. Wilson, Eduardo Torres, Sudhanshu Srivastava, Richard Lawson, Robbie W. J. M. Hanssen
  • Patent number: 10591392
    Abstract: A biopsy-sized tissue sample is stained for quick imaging. A significant amount of permeation enhancer is included in a mixed solution of permeant enhancer, fixative or dehydrant, and one or two fluorescent dyes to simultaneously dehydrate and dye the tissue sample. The permeation enhancer, e.g., 10% to 50% in the mixed solution, achieves an image of dyed tissue in the contacted tissue sample at a depth of at least 200 um within no more than 1.5 hours. One of the fluorescent dyes is a fluorescent nuclear dye such as DAPI, SYTOX green, acridine orange, propidium iodide, or a Hoechst dye. The other fluorescent dye is a fluorescent protein dye such as eosin or rhodamine B. The tissue sample is cleared with a clearing agent having a refractive index of at least 1.4[R2], e.g., using BABB. The mixed solution may further include Chloroform or other morphology preservative.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: March 17, 2020
    Assignee: APPLIKATE TECHNOLOGIES LLC
    Inventors: Richard Torres, Michael Levene
  • Patent number: 10527528
    Abstract: The present invention relates to systems and methods for tissue processing and analysis. Tissue chambers are configured to allow single-container chemical processing, imaging, and wax embedding of tissue samples in a single container without manipulation between steps. Tissue chambers with features to support the tissue sample and allow fluid flow between the tissue sample and the tissue chamber surface are disclosed. The features may be index matched to sample structures of interest or dissolvable in clearing solution to allow for in-chamber imaging with minimal distortion. Specialized tissue processing and wax removal apparatuses are also disclosed including for use with tissue chambers having frangible portions to permit ease of wax removal.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: January 7, 2020
    Assignee: APPLIKATE TECHNOLOGIES LLC
    Inventors: Michael Levene, Richard Torres
  • Publication number: 20190360901
    Abstract: The present invention relates to systems and methods for tissue processing and analysis. Tissue chambers are configured to allow single-container chemical processing, imaging, and wax embedding of tissue samples in a single container without manipulation between steps. Tissue chambers with features to support the tissue sample and allow fluid flow between the tissue sample and the tissue chamber surface are disclosed. The features may be index matched to sample structures of interest or dissolvable in clearing solution to allow for in-chamber imaging with minimal distortion. Specialized tissue processing and wax removal apparatuses are also disclosed including for use with tissue chambers having frangible portions to permit ease of wax removal.
    Type: Application
    Filed: October 18, 2018
    Publication date: November 28, 2019
    Inventors: Michael Levene, Richard Torres
  • Publication number: 20190211090
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Application
    Filed: February 21, 2019
    Publication date: July 11, 2019
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Lynn MACDONALD, Richard TORRES, Marc R. MORRA, Joel H. MARTIN, Joel C. REINHARDT, Paul TISEO
  • Patent number: 10266588
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: April 23, 2019
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Lynn MacDonald, Richard Torres, Marc R. Morra, Joel H. Martin, Joel C. Reinhardt, Paul Tiseo
  • Publication number: 20160237148
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Application
    Filed: May 2, 2016
    Publication date: August 18, 2016
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Lynn MACDONALD, Richard TORRES, Marc R. MORRA, Joel H. MARTIN, Joel C. REINHARDT, Paul TISEO
  • Patent number: 9353176
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: May 31, 2016
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Lynn MacDonald, Richard Torres, Marc R. Morra, Joel H. Martin, Joel C. Reinhardt, Paul Tiseo
  • Publication number: 20160003716
    Abstract: The present invention includes novel methods of processing a tissue sample. The present invention also includes novel methods of imaging a tissue sample. The present invention further includes a specimen holding device for performing the novel methods of processing a tissue sample and a microscope system for performing the novel methods of imaging a tissue sample.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 7, 2016
    Inventors: Richard Torres, Michael Levene
  • Publication number: 20160003715
    Abstract: The present invention includes novel methods of processing a tissue sample. The present invention also includes novel methods of imaging a tissue sample.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 7, 2016
    Inventors: Richard Torres, Michael Levene
  • Publication number: 20140220023
    Abstract: Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved.
    Type: Application
    Filed: September 26, 2013
    Publication date: August 7, 2014
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: LYNN MACDONALD, RICHARD TORRES, MARC R. MORRA, JOEL H. MARTIN, JOEL C. REINHARDT, PAUL TISEO
  • Patent number: D866666
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: November 12, 2019
    Assignee: INCREDIBLE TECHNOLOGIES, INC
    Inventors: Richard A Ditton, Larry Hodgson, Omar Torres, Bryan McVey, George Biggs, Matthew Randazzo
  • Patent number: D866668
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: November 12, 2019
    Assignee: INCREDIBLE TECHNOLOGIES, INC.
    Inventors: Richard A Ditton, Larry Hodgson, Omar Torres, Bryan McVey, George Biggs
  • Patent number: D882754
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: April 28, 2020
    Assignee: Presspart GmbH & Co. KG
    Inventors: Richard Turner, Benjamin Jung, Dana Shears, Hans-Peter Schmelzer, David Hibbard, Benjamin Glace, Douglas Browne, Karl Edward Robinson, Victor Torres