Abstract: This invention relates to compounds and methods for the treatment of cancer. In particular, the invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising the compounds, and methods of using the compounds for the treatment of cancer.

Abstract: According to one of the aspects of the present invention there is provided a substrate carrier arranged to hold a substrate in position using a vacuum, the vacuum being established in a sealed space created between the substrate carrier and the substrate.

Abstract: A color television receiver circuit for preventing excessive X-radiation is described. A spark gap is coupled between the high voltage supply for the color tube and ground. Should the high voltage output tend to exceed a level beyond which undesirable X-radiation may be emitted, the spark gap breaks down, effectively shorting the high voltage output to ground and preventing the excessive voltage condition. At the same time, the picture is eliminated and the viewer must have the set serviced. Two embodiments are described in detail. In one, the spark gap is built into the tube socket of a high voltage rectifier; in the other, the spark gap is incorporated into a voltage multiplier circuit.