Patents by Inventor Richard Truran

Richard Truran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MANUFACTURING GENE THERAPY VECTORS
    Publication number: 20210355503
    Abstract: Disclosed are methods for the production and/or purification of a recombinant AAV (rAAV) particle from a mammalian host cell culture.
    Type: Application
    Filed: September 23, 2019
    Publication date: November 18, 2021
    Inventors: Julian Hanak, Richard Truran
  • AAV COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE
    Publication number: 20210145929
    Abstract: Disclosed are methods for the purification of a recombinant AAV (rAAV) particle from a mammalian host cell culture. The disclosure further provides a pharmaceutical composition produced by the methods of the disclosure, pharmaceutical compositions and method of using the pharmaceutical compositions described herein for the treatment of disease.
    Type: Application
    Filed: April 5, 2019
    Publication date: May 20, 2021
    Inventors: Valerie Girard, Richard Truran, Tuyen Ong
  • TREATMENT OF RETINITIS PIGMENTOSA
    Publication number: 20200353098
    Abstract: A polynucleotide comprising a nucleotide sequence encoding the retinitis pigmentosa GTPase regulator ORF15 isoform (RPGRORF15) wherein the RPGRORF15 encoding nucleotide sequence has been codon optimised to increase fidelity of replication and wherein the sequence comprises one or more nucleotides selected from: C at the position corresponding to position 1968 of SEQ ID NO: 2, A at the position corresponding to position 2088 of SEQ ID NO: 2, and C at the position corresponding to position 2205 of SEQ ID NO: 2.
    Type: Application
    Filed: March 16, 2018
    Publication date: November 12, 2020
    Inventors: Julian Hanak, Richard Truran, Gregory Robinson, Scott Loiler
  • Virus purification
    Patent number: 10273502
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: April 30, 2019
    Assignee: Oxford BioMedica (UK) Limited
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus Purification
    Publication number: 20170175135
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: September 14, 2015
    Publication date: June 22, 2017
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus Purification
    Publication number: 20170073702
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 16, 2017
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus purification
    Patent number: 9169491
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilization step wherein the filter-sterilization step is not the final step in the purification process.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 27, 2015
    Assignee: Oxford BioMedica (UK) Limited
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • VIRUS PURIFICATION
    Publication number: 20090325284
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: June 18, 2009
    Publication date: December 31, 2009
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous