Abstract: Dynamic allocation of power modules for charging electric vehicles is described herein. The charging system includes multiple dispensers that each include one or more power modules that can supply power to any one of the dispensers at a time. A dispenser includes a first power bus that is switchably connected to one or more local power modules and switchably connected to one or more power modules located remotely in another dispenser. The one or more local power modules are switchably connected to a second power bus in the other dispenser. The dispenser includes a control unit that is to cause the local power modules and the remote power modules to switchably connect and disconnect from the first power bus to dynamically allocate the power modules between the dispenser and the other dispenser.

Abstract: The present disclosure details systems, computer program products, and methods for machine engine analysis of network interaction data to identify conflicts. This involves the activation of an intelligence engine that connects to a backend data engine to access a database of conflict of interest (COI) datasets. The intelligence engine analyzes incoming applicant data and the COI datasets to identify potential conflicts. The identified conflicts are validated using stochastic metrics via a rules engine. A quantifiable probability metric is calculated, representing the probability of conflict from both organizational and individual perspectives. Based on the potential conflict of interest, a recommendation is generated that aligns with the calculated probability. The system then provides recommendations via API or on a user interface that is communicatively coupled to the processor.

Abstract: A system is provided for computing and tracking resource state changes using a multichain distributed register technology. In particular, the system may comprise an index distributed register that may be stored across a plurality of distributed register nodes. The index distributed register may comprise one or more resource-specific data records that may in turn make up a resource-specific distributed register originating from the index distributed register. The resource-specific distributed register may comprise an initial data record that defines the attributes of the resource, and one or more subsequent data records that may be linked with the initial data record to reflect changes in the state of the resource to be tracked. Based on the data within each of the resource-specific distributed register, the system may compute resource analysis scores and/or trigger real-time user alerts.

Abstract: Techniques are disclosed to provide an interactive visual representation of semantically related extracted data. In various embodiments, a plurality of data entities are extracted from a file, each entity comprising a key-value pair. One or more sets of related entities, each set comprising an occurrence of a defined repeating type of entity set, are identified among the plurality of data entities. Data associating the one or more sets of related entities with the file and the defined repeating type of entity set are stored.

Abstract: A technique for providing real time feedback from a machine learning system is provided that includes a method and system for interactively training machine learning models. In particular, by separating processing and analysis using static and dynamic models that are trained differently, the disclosed technique enables interactive training and prediction of machine learning models to increase the speed of generating new predictions based on real time feedback. In some cases, a dynamic model is applied to the output of a static model to generate an analysis, a correction of the analysis is received, and the correction is used to retrain the dynamic model. An updated analysis is generated based on reapplying the dynamic model to the output of the static model without having to retrain the static model.

Abstract: Disclosed herein are antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof that bind human CD48. Also disclosed are pharmaceutical compositions comprising the antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof; and methods of making and using such pharmaceutical compositions for treating cancer in a patient in need of treatment.

Abstract: Techniques are disclosed to provide an interactive visual representation of semantically related extracted data. In various embodiments, a plurality of data entities are extracted from a file, each entity comprising a key-value pair. One or more sets of related entities, each set comprising an occurrence of a defined repeating type of entity set, are identified among the plurality of data entities. Data associating the one or more sets of related entities with the file and the defined repeating type of entity set are stored.

Abstract: Antibody-drug conjugates that bind to human oncology targets are disclosed. The antibody-drug conjugates comprise a Bcl-xL inhibitor drug moiety. The disclosure farther relates to methods and compositions for use in the treatment of cancers by administering the antibody-drug conjugates provided herein. Linker-drug conjugates comprising Bcl-xL inhibitor drug moiety and methods of making same are also disclosed.

Abstract: Disclosed herein are antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof that bind human CD48. Also disclosed are pharmaceutical compositions comprising the antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof; and methods of making and using such pharmaceutical compositions for treating cancer in a patient in need of treatment.

Abstract: Anti-CD48 antibody-drug conjugates are disclosed. The anti-CD48 antibody-drug conjugates comprise an Mcl-1 inhibitor drug moiety and an anti-CD48 antibody or antigen-binding fragment thereof that binds an antigen target, e.g., an antigen expressed on a tumor or other cancer cell. The disclosure further relates to methods and compositions for use in the treatment of cancers by administering the antibody-drug conjugates provided herein. Linker-drug conjugates comprising an Mcl-1 inhibitor drug moiety and methods of making same are also disclosed.

Abstract: Disclosed herein are antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof that bind human CD48. Also disclosed are pharmaceutical compositions comprising the antibodies, antigen binding fragments thereof, and antibody drug conjugates thereof; and methods of making and using such pharmaceutical compositions for treating cancer in a patient in need of treatment.

Abstract: A link assembly has a pair of mechanical links pivotally connected to rotate relative to one another about a pivot axis. A cable protector is provided as part of the link assembly. The cable protector has a cup with an end wall which defines a first end of a winding chamber, and an annular side wall which extends from the end wall and defines a side of the winding chamber. A lid defines a second end of the winding chamber opposite to the first end. The lid is coupled to the cup by a bearing so that the cup and lid can rotate with respect to each other. An opening is formed in the side wall of the cup and a slot is formed in the lid. The assembly is fitted with a cable having a length, a width, and a thickness, wherein the width of the cable is greater than its thickness.

Abstract: A link assembly has a pair of mechanical links pivotally connected to rotate relative to one another about a pivot axis. A cable protector is provided as part of the link assembly. The cable protector has a cup with an end wall which defines a first end of a winding chamber, and an annular side wall which extends from the end wall and defines a side of the winding chamber. A lid defines a second end of the winding chamber opposite to the first end. The lid is coupled to the cup by a bearing so that the cup and lid can rotate with respect to each other. An opening is formed in the side wall of the cup and a slot is formed in the lid. The assembly is fitted with a cable having a length, a width, and a thickness, wherein the width of the cable is greater than its thickness.

Abstract: A computer system generates medical messages based on an analysis of medical information associated with healthcare providers. The analyzed medical information may be derived from medical records and/or insurance claims, such as those that may be managed by a clearing house entity that manages the processing of medical insurance claims. Healthcare providers having certain patients that meet various analysis criteria may be identified for purposes of generating the messages that can serve to inform the health care providers about potential medical treatments and procedures, such as new drugs, that be significant for the health care provider and may also be significant to the patients of the health care provider who may be identified in the messages.

Abstract: A system and method for managing reservation requests for one or more inventory items are provided. A user reservation request is obtained and processed to identify inventory data matching the reservation request. Reservation transaction, reservation items and reservation inventory records are generated corresponding to the user reservation request. If the transaction can be completed, a confirmation is sent to the user and a notification is sent to a supplier.

Abstract: A system and method for managing reservation requests for one or more inventory items are provided. A user reservation request is obtained and processed to identify inventory data matching the reservation request. Reservation transaction, reservation items and reservation inventory records are generated corresponding to the user reservation request. If the transaction can be completed, a confirmation is sent to the user and a notification is sent to a supplier.

Abstract: A system and method for managing inventory data are provided. A travel server obtains inventory data from one or more inventory suppliers and stores the inventory data as SKU group, SKU and SKU inventory records. The travel server utilizes the SKU group, SKU and SKU inventory records. The travel server utilizes the SKU group, SKU and SKU inventory records to process user requests for available inventory and supplier inventory action requests.

Abstract: A system and method for managing inventory data are provided. A travel server obtains inventory data from one or more inventory suppliers and stores the inventory data as SKU group, SKU and SKU inventory records. The travel server utilizes the SKU group, SKU and SKU inventory records to process user requests for available inventory and supplier inventory action requests.

Abstract: The invention relates to a method for producing hydroxylated triple helical proteins in yeast host cells by introducing to a suitable yeast host cell, DNA sequences encoding the triple helical protein as well as prolyl 4-hydroxylase (PH4), in a manner wherein the introduced DNA sequences are replicated, stably retained and segregated by the yeast host cells.

Abstract: An in-vehicle coffee maker includes a coffee mug and a brewing station that receives the mug, and has a lid that secures the mug therein. A pump supplies water to the lid from a water reservoir via a water line. A heating element heats the water to a predetermined temperature. The mug includes a mug portion, a drink cap, and a pod retainer. The drink cap includes a pod chamber to hold coffee grounds, and the pod retainer secures the coffee grounds therein. The pod retainer includes a opening for water to pass through, into the pod chamber, which in turn includes an opening for water to drain downward into the mug. The lid of the brewing station includes a nozzle that forms a sealed engagement with the opening in the pod retainer so water supplied from the reservoir to the lid flows into the pod chamber.