Patents by Inventor Richard Versace

Richard Versace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY
    Publication number: 20170157134
    Abstract: A pharmaceutical combination comprising (a) a compound of formula (I), or pharmaceutically acceptable salts thereof; and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway; the uses of such combination in the treatment or prevention of proliferative diseases; and methods of treating a subject suffering.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Inventors: Qing Sheng, Hui-Qin Wang, Fang Li, Jinsheng Liang, Zhu Alexander Cao, John Monahan, Richard Versace
  • COMBINATION THERAPY
    Publication number: 20160287605
    Abstract: A pharmaceutical combination comprising (a) a compound of formula (I), or pharmaceutically acceptable salts thereof; and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway; the uses of such combination in the treatment or prevention of proliferative diseases; and methods of treating a subject suffering.
    Type: Application
    Filed: June 16, 2016
    Publication date: October 6, 2016
    Applicant: Novartis AG
    Inventors: Qing Sheng, Hui-Qin Wang, Fang Li, Jinsheng Liang, Zhu Alexander Cao, John Monahan, Richard Versace
  • COMBINATION THERAPY
    Publication number: 20150290204
    Abstract: A pharmaceutical combination comprising (a) a compound of formula (I), or pharmaceutically acceptable salts thereof; and (b) one or more at least one compound targeting, decreasing or inhibiting the intrinsic ATPase activity of Hsp90 and/or degrading, targeting, decreasing or inhibiting the Hsp90 client proteins via the ubiquitin proteosome pathway; the uses of such combination in the treatment or prevention of proliferative diseases; and methods of treating a subject suffering from a proliferative disease; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 15, 2015
    Applicant: Novartis AG
    Inventors: Qing Sheng, Hui-Qin Wang, Fang Li, Jinsheng Liang, Zhu Alexander Cao, John Monahan, Richard Versace
  • 1,4-Disubstituted isoquinilone derivatives as raf-kinase inhibitors useful for the treatment of proliferative diseases
    Publication number: 20070060582
    Abstract: This invention relates to compounds of the formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 15, 2007
    Inventors: Cynthia Fink, Lawrence Perez, Timothy Ramsey, Naeem Yusuff, Richard Versace, David Batt, Michael Sabio, Sunkyu Kim
  • Substituted lactams and their use as anti-cancer agents
    Publication number: 20060281731
    Abstract: This invention relates to certain substituted lactam compounds of the formula (I), particularly caprolactam compounds, which are useful for the treatment of cancer.
    Type: Application
    Filed: July 23, 2004
    Publication date: December 14, 2006
    Inventors: Kenneth Walter Bair, Frederick Kinder Jr., Richard Versace
  • Deacetylase inhibitors
    Publication number: 20060189674
    Abstract: The present invention provides hydroxamate compounds which are deacetylase inhibitors. The compounds are suitable for pharmaceutical compositions having anti-proliferative properties.
    Type: Application
    Filed: April 20, 2006
    Publication date: August 24, 2006
    Inventors: Stacy Remiszewski, Kenneth Bair, Richard Versace, Lawrence Perez, Michael Green, Lidia Sambucetti, Sushil Sharma
  • Deacetylase inhibitors
    Publication number: 20050085507
    Abstract: The present invention provides hydroxamate compounds which are deacetylase inhibitors. The compounds are suitable for pharmaceutical compositions having anti-proliferative properties.
    Type: Application
    Filed: November 9, 2004
    Publication date: April 21, 2005
    Inventors: Stacy Remiszewski, Kenneth Bair, Richard Versace, Lawrence Perez, Michael Green, Lidia Sambucetti, Sushil Sharma