Abstract: Apparatuses, systems, and methods for suppression of venous artifacts from superior tagging in flow-sensitive alternating inversion recovery. The systems may include an image capture device and a controller. The controller may be configured to cause the image capture device to perform a labeling experiment, capture a first image of a slice of body tissue, perform a control experiment, and capture a second image of the slice of body tissue. The systems may be configured to perform a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to the first slice of body tissue imaged during at least one of the labeling experiment and/or the control experiment, and to apply a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and/or the control experiment.

Abstract: Apparatuses, systems, and methods for suppression of venous artifacts from superior tagging in flow-sensitive alternating inversion recovery. The systems may include an image capture device and a controller. The controller may be configured to cause the image capture device to perform a labeling experiment, capture a first image of a slice of body tissue, perform a control experiment, and capture a second image of the slice of body tissue. The systems may be configured to perform a ninety (90) degree RF saturation pulse directed to a portion of body tissue that is superior to the first slice of body tissue imaged during at least one of the labeling experiment and/or the control experiment, and to apply a spoiler gradient subsequent to the saturation pulse during at least one of the labeling experiment and/or the control experiment.

Abstract: Methods, devices, and systems for creating an MRI image using an orthogonally positioned tagging imaging method for arterial labeling with FAIR. Embodiments of the present methods for creating an MRI image may include positioning a perfusion imaging plane that corresponds to an image target area of an imaging object, and causing an MRI image to be generated that corresponds to a representation of the image target area at the perfusion imaging plane. The perfusion imaging plane may be orthogonal to a direction of inflow from immediately proximal arteries of the image target area.

Abstract: A contrast agent adapted for magnetic resonance imaging of a sample, the contrast agent comprising a suspension in a medium acceptable for magnetic resonance imaging of (a) coated particles of a contrast agent possessing paramagnetic characteristics and (b) coated particles of a contrast agent possessing diamagnetic characteristics, each of the coatings being selected from a group of materials which [I] renders the coated particles (a) and (b) substantially comparable with and substantially biologically and substantially chemically inert to each other and the environments to which the contrast agent is exposed during magnetic resonance imaging and [II] which substantially stabilizes the suspension; the nature of each of the coatings and the relative amounts of (a) and (b) in the suspension being such that the positive magnetic susceptibility of (a) substantially offsets the negative magnetic susceptibility of (b) and the resulting suspension has substantially zero magnetic susceptibility and, when employed in

Abstract: A contrast agent useful for imaging a sample comprising a suspension in a medium acceptable for imaging (a) particles of a contrast agent possessing paramagnetic characteristics and (b) particles of a contrast agent possessing diamagnetic characteristics. Also disclosed is a method of imaging a sample which comprises introducing into the sample the above-described contrast agent and generating a substantially artifact-free image thereof. The combination of diamagnetic barium sulfate and superparamagnetic iron oxide (SPIO) in one suspension produces a macroscopic cancellation of positive and negative magnetic susceptibility components which eliminates susceptibility artifacts even with gradient echo pulse sequences. The relaxation properties which make the SPIO suspension a useful negative contrast agent are retained.