Patents by Inventor Richard W. Burack

Richard W. Burack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and Method for Detecting Population Variation from Nucleic Acid Sequencing Data
    Publication number: 20160034638
    Abstract: The present invention relates to a method of identifying genetic variants within a population of sequences. The method includes the steps of aligning a set of sequence data reads to reference sequences, dividing reference sequences into multiple tracks of overlapping regions of analysis (ROAs), partitioning each read into a ROA, identifying a plurality of sequence patterns in the reads, setting a sequence pattern frequency threshold value, eliminating any sequence pattern that has a value below the frequency threshold value forming a plurality of dictionaries from the sequence patterns having a value above the frequency threshold value, and cross-validating sequence patterns via partial sequence assembly. The method may optionally include amending the reference sequences used in iterative re-alignment of sequence data.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicant: University of Rochester
    Inventors: Janice M. Spence, John P. Spence, Richard W. Burack