Abstract: Parenteral delivery of a beneficial agent using an auto-injector configured for reduction of forces acting on a primary container for the beneficial agent during activation of the auto-injector. The primary container may be disposed within a pressure chamber of the auto-injector such that an increased pressure within the pressure chamber during activation is applied to a stopper of the primary container and an external surface of a sidewall of the primary container. In turn, a pressure differential between a containment volume of the primary container and the pressure chamber may be reduced or eliminated. In turn, forces acing on the primary container in response to the pressure increase in the pressure container may be reduced or eliminated. Configurations are also provided for improved relative movement between a stopper and a sidewall of the primary container for more reliable injection.

Abstract: A source fluid inlet for an automated filling device. The source fluid inlet may comprise features that limit engagement and/or disengagement of a source fluid tubing set from a port in the source fluid inlet except when the port is disposed in a predetermined load position. In turn, engagement and/or disengagement of the source fluid tubing may be selectively allowed to assist in reduction of interconnection errors of one or more source fluid sources. The source fluid inlet may selectively position a source fluid tubing set in a fill position to facilitate fluid communication with a receptacle to be filled (e.g., a syringe). The source fluid inlet further comprises one or more mechanisms for engagement and/or retention of a cap disposed on a syringe.

Abstract: A source fluid inlet for an automated filling device. The source fluid inlet may comprise features that limit engagement and/or disengagement of a source fluid tubing set from a port in the source fluid inlet except when the port is disposed in a predetermined load position. In turn, engagement and/or disengagement of the source fluid tubing may be selectively allowed to assist in reduction of interconnection errors of one or more source fluid sources. The source fluid inlet may selectively position a source fluid tubing set in a fill position to facilitate fluid communication with a receptacle to be filled (e.g., a syringe). The source fluid inlet further comprises one or more mechanisms for engagement and/or retention of a cap disposed on a syringe.

Abstract: A lancing device has a spring-loaded lancet holder slidably mounted within a housing for carrying a disposable lancet and needle. A slider mounted in a slot in the housing is moved back for cocking the device and, after the lancet is fired, is moved forward to eject the used lancet. A releasable connector reversibly immobilizes the holder while the lancet is being ejected. The releasable connector permits a shortened ejection stroke, which, in turn, permits a shorter slot in the housing.

Abstract: A lancing device has a spring-loaded lancet holder slidably mounted within a housing for carrying a disposable lancet and needle. A knob on the back of the device has forward-extending fingers that stop the lancet holder at an adjustable predetermined point after the device has been fired. The fingers not only control the penetration depth of the needle, but also absorb vibrations and reduce noise to cause less pain to the user.