Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: A charging system for a vehicle. The charging system includes an on-board battery, a charger region and a wireless receiver for generating a charging signal in the charger region to charge a battery. The system also includes a plurality of sensors located to sense living beings and foreign objects in proximity to the charger region. The system further includes a controller for filtering transient conditions and terminating the charging signal when a being or a foreign object is near the charger region.

Abstract: Vaccine antigen formulations that are stable after undergoing freeze and thaw conditions and methods of preparing the formulations are provided. Methods of using the formulations to prepare vaccine are also provided. Vaccines comprising the formulations are useful, for example, to protect against, inhibit or alleviate a disease or infection, such as related to anthrax infection.

Abstract: A computer system arranged to determine whether a candidate media-component matches one or more reference media-components, wherein the computer system comprises: at least one processing device arranged to receive the candidate media-component and the at least one processing device further comprising: a window generator arranged to select a portion of the can didate media-component; a fingerprint generator arranged to generate a fingerprint from the portion of the candidate media-component selected by the window generator, wherein the at least one processing device is arranged to cause the window generator to move through the candidate media component thereby selecting a plurality of portions of the candidate media component from at least some of which the fingerprint generator is arranged to generate a candidate fingerprint thereby creating a sequence of candidate fingerprints; a comparator arranged to compare at least some of the candidate fingerprints within the sequence of candidate fingerprints against f

Abstract: Methods, systems, and computer program products are provided for workflow decision management. Embodiments include maintaining a device state history; identifying a device usage pattern in dependence upon the device state history; and identifying a derived scenario in dependence upon the device usage pattern. The derived scenario has a tolerance. Embodiments also include identifying a workflow in dependence upon the derived scenario and executing the workflow in dependence upon the tolerance.

Abstract: Gas turbine engine turbine blade assembly includes a hollow airfoil joined to blade root, dovetail slot heat shield bonded or attached to a bottom surface of the root, and a shield outlet from heat shield open to inlet apertures extending radially through a radially inner root end of the root. Heat shield may have body with legs extending upwardly from heat shield bottom, slanted open upstream end, and free ends of the legs longer than the heat shield bottom. Flanges may be located along free ends and bonded to bottom surface. Body, heat shield bottom and/or the legs may be rounded. Disk includes a plurality of dovetail slots formed in a rim, complimentary plurality of turbine blades removably retained in dovetail slots by the roots, slot bottoms of the dovetail slots extending circumferentially between disk posts in rim. Heat shield bottoms may be radially spaced apart the slot bottoms.

Abstract: The invention provides a composition comprising a reduced toxicity NetB epitope polypeptide and a reduced toxicity Clostridium perfringens alpha-toxin epitope polypeptide. The composition is useful as a vaccine providing complete protection against infection by C. perfringens.

Abstract: Systems for selecting, generating, and breeding hybrid dairy cattle are described, as are methods for maintaining herds of hybrid cattle.

Abstract: A system and method for controlling media through a user interface integrated within a taskbar is described. This system and method enable a user to control media while a user interface of another application remains in perspective. Further, this system includes a taskbar media player, which can play media and enable a user to control the play of that media from within a taskbar.

Abstract: Time-varying passwords for user authentication are disclosed. Example methods disclosed herein for password generation include obtaining a base password including characters, determining a first character position of the base password at which a first time-varying data element is to be inserted to determine a time-varying password, the first time-varying data element to be computed based on a time-varying parameter, and determining a first offset to be applied to a value of the time-varying parameter to compute the first time-varying data element. Example methods disclosed herein for password evaluation include accessing a base password including characters, applying a first offset to a value of a time-varying parameter to determine a first time-varying data element to be inserted at a first character position of the base password to determine a time-varying password, and comparing the time-varying password with an input password to perform authentication based on the input password.

Abstract: A system for monitoring/confirming the location of and communicating with a group of user devices or individual members thereof is generally represented by reference numeral 1. The system 1 comprises a mobile application or website executable on a mobile device 2 such as a smartphone. The mobile application enables users to associate mobile devices to form groups 3 of such devices. The system 1 also has a location confirmation member in the form of a Bluetooth low energy beacon and/or sonic signal beacon 4 and/or GPS system 15 for determining which mobile devices 2 associated with a formed group 3 are present in a pre-defined location or area 5, and given this information communicates collectively or individually with those mobile devices 2 which are associated with a formed group 3 and have been determined as present in the pre-defined location or area 5 at the time of said communication.

Abstract: Disclosed is a high thermal conductivity composite baseplate (“HTCCB”) for use with an electronics package on a vehicle. The HTCCB may include a first boron and carbon fiber layer and a second boron and carbon fiber layer. Additionally, the HTCCB may also include a carbon nanotube (“CNT”) material bonding the first boron and carbon fiber layer to the second boron and carbon fiber layer and a plurality of CNTs within the CNT material.

Abstract: Disclosed is a thermal conductive joint between a face-sheet and a heat-pipe on a radiator panel. The thermal conductive joint includes an adhesive layer attached between the face-sheet and the heat-pipe and a plurality of carbon nanotubes (“CNTs”) within the adhesive layer.

Abstract: A turbine disk and blade assembly comprises a turbine disk including a plurality of disk posts extending radially therefrom and a plurality of disk slots between adjacent disk posts. The turbine disk is of a first material having a first coefficient of thermal expansion. The assembly further comprises a plurality of turbine blades. One of the turbine blades is received in each disk slot. The turbine blades are of a second material having a second coefficient of thermal expansion. The assembly further comprises a plurality of seal plates, wherein one of the seal plates is positioned in each disk slot radially inward of the turbine blade. The seal plates are of a material having a coefficient of thermal expansion substantially similar to that of either the disk posts or the turbine blade.

Abstract: Systems and methods for using secondary communication channel information, such as RTCP information to facilitate correlating business information to allow gateway recording. Using information in this secondary communication channel the recording system can correlate the business metadata either directly (e.g., using a phone extension) or through one or more indirect operations (e.g., a call ID-to-universal call id-to-phone extension). Additionally, information in the primary communication channel may be used to perform an indirect operation to correlate auxiliary business information (e.g., using the CALLID or UCID in SIP signaling to resolve the agent's phone extension and thereby access auxiliary business information.

Abstract: A user (18) views a reference symbol (36) along a line of sight (28) intersected by an image intensifier (22), arranged to present an intensified image of a forward scene (26) to the eye (24) of the user (18), and an image display (14), arranged to display an image to the eye (24) of the user (18) overlaid on the intensified image. The user indicates alignment of first and alternate symbols generated at known positions on the image display (14) with the reference symbol (36) and the position of a helmet (16) carrying the image display (14) is determined by a helmet tracking system (30) for each alignment. A line of sight can be determined for each symbol alignment given the helmet (16) position and known location of the first and alternate symbols. These lines of sight can be used to determine the magnification factor of the forward scene (26) induced by the image intensifier (20).

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: According to one embodiment, there is disclosed an inducer assembly for use with a gas turbine engine. The inducer assembly may include a cavity. The inducer assembly may also include an inducer in fluid communication with the cavity. Moreover, the inducer assembly may include at least one guide vane disposed within the cavity.

Abstract: A new cultivar of Cosmos plant named ‘Hamcosp’ that is characterized by large diameter crimson red inflorescences with yellow pollen and broad pinnate leaves.