Patents by Inventor Richard Woychik

Richard Woychik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Allelic series of genomic modifications in cells
    Publication number: 20050191658
    Abstract: The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e.g., chemicals, electromagnetic radiation, etc.) to introduce modifications in any nucleic acid sequence in the genome of a cell. Also provided are sets of cells which contain at least one modification in any gene of interest. The methods and compositions of the invention are useful in determining the function of the gene of interest.
    Type: Application
    Filed: November 22, 2004
    Publication date: September 1, 2005
    Inventors: Richard Woychik, Terry Magnuson, Ellis Avner
  • Allelic series of genomic modifications in cells
    Publication number: 20050186675
    Abstract: The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e.g., chemicals, electromagnetic radiation, etc.) to introduce modifications in any nucleic acid sequence in the genome of a cell. Also provided are sets of cells which contain at least one modification in any gene of interest. The methods and compositions of the invention are useful in determining the function of the gene of interest.
    Type: Application
    Filed: November 22, 2004
    Publication date: August 25, 2005
    Applicant: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Richard Woychik, Terry Magnuson, Ellis Avner
  • Efficient construction of gene targeting using phage-plasmid recombination
    Patent number: 6221647
    Abstract: A method for producing gene targeting constructs in bacterial by way of homologous recombination between bacterial phage and plasmids.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: April 24, 2001
    Assignee: Amgen, Inc.
    Inventor: Richard Woychik
  • Efficient construction of gene targeting using phage-plasmid recombination
    Patent number: 6090629
    Abstract: A method for producing gene targeting constructs in bacterial by way of homologous recombination between bacterial phage and plasmids.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: July 18, 2000
    Assignee: Amgen, Inc.
    Inventor: Richard Woychik
  • Efficient construction of gene targeting vectors
    Patent number: 6090554
    Abstract: The present invention is directed to methods for producing or obtaining gene targeting constructs by way of homologous recombination in host cells and to targeting constructs produced by those methods. The invention is also directed to transgenic animals having targeted mutations introduced in to the cells of the animal using the targeting constructs of the invention.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: July 18, 2000
    Assignee: Amgen, Inc.
    Inventors: Richard Woychik, David Garfinkel