Abstract: The present invention relates generally to systems, devices and methods for the efficient use of utilities, more particularly to the distribution and provision of electricity supply at appropriate voltages, monitoring and usage by end devices, and to facilitating consumers in changing their energy usage behaviour, and to adopt and easily install appropriate sustainable, energy efficient or renewable technologies. Said end devices typically including traditional electric, electronic and lighting appliances requiring AC or DC power provision or low voltage DC power via AC/DC converters.

Abstract: Disclosed herein are binding moieties that comprise non-CDR loops for masking the binding of a binding molecule to its target and CDRs for binding bulk serum proteins. Conditionally active target binding proteins that contain the binding moieties are also provided. Cleavable linkers used in the conditionally active target binding proteins are also disclosed.

Abstract: A drainage-optimized additive composition for papermaking is disclosed. The composition comprises an aqueous media, a glyoxalated polyacrylamide (GPAM) resin, and an anionic polyacrylamide (APAM) resin. The GPAM resin has a weight average molecular weight (Mw) of at least about 5 MDa and a cationic monomer content of at least about 4 mol %. The APAM resin has a Mw of at least about 0.25 MDa, and an anionic monomer content up to about 25 mol %. A method of preparing the additive composition is also disclosed, and comprises preparing a cationic acrylamide (CPAM) prepolymer having a predetermined cationic monomer, selectively glyoxalating the CPAM prepolymer in aqueous media during glyoxalation to give the GPAM resin, and combining the GPAM and APAM resins. The method may be carried out in situ during a papermaking process (i.e., as an on-site method), and may be implemented in different forms during the process of forming paper.

Abstract: Methods and systems for determination of flow parameters of administered fluid from a radioembolization delivery device may include translationally moving a device delivery arm of the radioembolization delivery device in a translational direction, wherein the device delivery arm is coupled to a syringe holder such that move in the translational direction one of proximally or distally advances the syringe holder; sensing, via one or more pattern sensors, a corresponding movement of a pattern associated with the translational device delivery arm movement as a sensed pattern movement; generating, via the one or more pattern sensors, one or more output signals based on the sensed pattern movement; and generating, via a processor, a flow rate of the administered fluid, a flow amount of the administered fluid, and/or the translational direction of movement of the device delivery arm with respect to the syringe holder based on the one or more output signals.

Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: An improved data structure approach, and corresponding computational systems and methods are described to provide a technical approach that can be used for improving computational performance where a blockchain data structure is being accessed continuously or periodically for validation of recordals of one or more events that have taken place. A hybrid off-chain (or off-contract)/on-chain solution is utilized to provide a mechanism for establishing data linkages between the off-chain (or off-contract) records and on-chain data payloads.

Abstract: Systems and methods are provided for interconnecting proxy directories, through core proxy services. One example computer-implemented method includes receiving, by a first proxy service core computing device, from a participant, a proxy lookup request, where the proxy lookup request includes a proxy and based on one or more routing rules, submitting the proxy lookup request to a second proxy service core computing device. The method also includes receiving, by the first proxy service core computing device, from the second proxy service core computing device, a proxy lookup response, which includes account data linked to the proxy, and returning the proxy lookup response, to the participant, in response to the proxy lookup request.

Abstract: The present disclosure describes methods and systems for interpreting a user external data reference value and a user data change input value, accessing an external data source in response to the user external data reference value, receiving source data from the external data source, updating the source data in the external data source in response to the external data source and the user data change input value, and providing an updated display value for a document in response to the user data change input value and the source data.

Abstract: Systems and methods include interpreting a first user input from a first user, the first user input comprising a text flow entry, interpreting a second user input from the first user, the second user input comprising at least one of: an in-line data access entry or a table-based calculation entry, positioning a text entry value on a unified document surface in response to the first user input, creating at least one data structure in response to the second user input, the at least one data structure comprising data from an external data source, the external data source being external to the unified document surface, and positioning the at least one data structure on the unified document surface.

Abstract: The present disclosure describes methods and systems for a accessing a data element, providing a first view in response to the data element, the first view comprising at least a portion of the data element, determining a visualization element (VE) in response to the data element, and further in response to at least one of a user visualization selection or a user context value, and providing a second view in response to the VE and the data element.

Abstract: The present disclosure describes methods and systems for interpreting a table grouping input value associated with a table, wherein the table comprises a plurality of categories and a plurality of associated data sets corresponding to the plurality of categories, determining an aggregation value in response to the table grouping input value, wherein the aggregation value corresponds to at least one of the plurality of categories, and in response to the aggregation value, providing an aggregated table view.

Abstract: An improved data structure approach, and corresponding computational systems and methods are described to provide a technical approach that can be used for improving computational performance where a blockchain data structure is being accessed continuously or periodically for validation of recordals of one or more events that have taken place. A hybrid off-chain (or off-contract)/on-chain solution is utilized to provide a mechanism for establishing data linkages between the off-chain (or off-contract) records and on-chain data payloads.

Abstract: The present invention relates to an apparatus for providing respiratory assistance to a user via a user conduit. The apparatus being operable in a humidifying mode and a non-humidifying mode, and includes a humidification chamber for containing an amount of water that can be located in an operating position in the humidifying mode and, optionally separate from the apparatus in the non-humidifying mode. The apparatus may also have an auxiliary flow path that can be activated in the non-humidifying mode and a powered device that heats water in the humidification chamber when the apparatus is in the humidifying mode.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.

Abstract: A control knob lockout device for rendering knobs of a stove inoperable includes a pair of latches, a pair of keepers, and a housing. The latches are mountable to a stove so that the latches are positioned singly proximate to opposed sides of the stove. The latches also are positioned in substantial alignment with a set of control knobs that is engaged to a surface of the stove. The housing defines an interior space and has a rear face. The rear face has an opening positioned therein to insert the set of control knobs so that the housing is positioned thereover. The pair of keepers is engaged to a front face of the housing. Each keeper is positioned proximate to a respective opposed end of the housing and selectively engages a respective latch to fixedly position the housing over the set of control knobs.

Abstract: The present disclosure relates to an apparatus that can be used to humidify a stream of air that may be delivered to a patient for respiratory assistance during Positive Airway Pressure (PAP) therapy. The apparatus includes a humidification chamber and compartment that receives the humidification chamber in which the humidification chamber is secured in the compartment to enhance thermal engagement, for example, between a heater plate of the compartment and a heater base of the humidification chamber.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: The present disclosure describes methods and systems for interpreting a table grouping input value associated with a table, wherein the table comprises a plurality of categories and a plurality of associated data sets corresponding to the plurality of categories, determining an aggregation value in response to the table grouping input value, wherein the aggregation value corresponds to at least one of the plurality of categories, and in response to the aggregation value, providing an aggregated table view.

Abstract: The present disclosure describes methods and systems for a document server communicatively coupled to at least one client computing device, a document comprising an operation log, wherein the operation log comprises at least one first sequential operation defining operations to create data values of the document, a document object model, wherein the document is at least partially positioned on at least one of the document server and a first client computing device of the at least one client computing device, and a formula engine, wherein the formula engine is structured to determine a calculation definition in response to the user formula value and the document object model.