Abstract: Presently provided are inhibitors of TD02 and IDO1 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2,3 dioxygenase and indoleamine 2,3-dioxygenase 1; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.

Abstract: An optical fiber transducer usable in environments of extreme operating temperature features a stationary support, a movable body displaceable back and forth relative thereto, and an optical fiber connected between the support and the movable body. The fiber has a Fiber Bragg Grating in an intermediate region thereof between the support and movable body. To accommodate varying coefficients of thermal expansion (CTEs) among these components, one or more tubes close circumferentially around the fiber. Each tube has a CTE that is greater than that of the fiber, and less than that of the constituent material of the support and movable body. The fiber is bonded to an interior of the tube(s), while an exterior of the tube(s) is bonded to the support and movable body.

Abstract: Systems/methods for monitoring and management of field devices and equipment at the edge provide an interworking component that runs on or at an edge device to facilitate monitoring and management of the field devices and equipment. In particular, the edge based interworking component allows operations, administration, and management (OA&M) services to be performed for both the hardware making up the devices as well as the operating systems and software applications running on the hardware. In some embodiments, OA&M services includes one or more IT orchestration services for the hardware as well as the operating systems and software applications running on the hardware. Such an arrangement allows monitoring and management of the field devices and equipment that have heretofore been performed by traditional control systems to be partly or entirely pushed down to the edge and/or pushed up to the cloud, depending on the particular implementation.

Abstract: A communication management resource receives input from a first wireless network. The input is generated in response to a mobile communication device requesting use of wireless services from the first wireless network; the first wireless network is operated by a first service provider. The communication management resource (such as in or associated with a second wireless network) allocates a network address for use by the mobile communication device. The network address is allocated by an allocation management resource in the second wireless network, which is operated by a second service provider. The communication management resource then communicates the allocated network address from the second wireless network through the first wireless network to the mobile communication device. The mobile communication device uses the network address to communicate through the first wireless network.

Abstract: Method for scanning for second object on or within first object starts by receiving information on first object and second object. Task lists are generated that include at least one task action based on information on first object and second object. Based on task lists, beamer is then signaled to generate and send first signal to first probe unit to perform first beam firing. Receiver processes first data signal from first probe unit that is then analyzed to determine if first object is identified using processed first data signal. Upon determination that first object is identified, based on task list, beamer is signaled to generate and send second signal to second probe unit to perform second beam firing. Receiver processes second data signal from second probe unit that is then analyzed to determine if second object is identified using processed second data signal. Other embodiments are described.

Abstract: According to certain aspects, a computer-implemented method for operating an autonomous or semi-autonomous vehicle may be provided. With the customer's permission, an identity of a vehicle operator may be identified and a vehicle operator profile may be retrieved. Operating data regarding autonomous operation features operating the vehicle may be received from vehicle-mounted sensors. When a request to disable an autonomous feature is received, a risk level for the autonomous feature is determined and compared with a driver behavior setting for the autonomous feature stored in the vehicle operator profile. Based upon the risk level comparison, the autonomous vehicle retains control of vehicle or the autonomous feature is disengaged depending upon which is the safer driver—the autonomous vehicle or the vehicle human occupant. As a result, unsafe disengagement of self-driving functionality for autonomous vehicles may be alleviated.

Abstract: The present disclosure provides an orthodontic article including the reaction product of the polymerizable composition. Further, the present disclosure provides polymerizable compositions and methods of making an orthodontic article. The method includes obtaining a polymerizable composition and selectively curing the polymerizable composition to form an orthodontic article. Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an orthodontic article; and generating, with the manufacturing device by an additive manufacturing process, the orthodontic article based on the digital object. A system is also provided, including a display that displays a 3D model of an orthodontic article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an orthodontic article.

Abstract: The disclosure relates to monitoring a state of a physical passenger transport system. In an aspect, monitoring includes use of an updated digital double dataset that reproduces characterizing properties of components of the physical passenger transport system in an actual configuration of the passenger transport system after assembly and installation thereof in a building, in a machine-processable manner. At least one detection device is arranged in the physical passenger transport system, which detects a load profile which is transmitted to the updated digital double dataset. A set of rules is used to convert the load profile into modified characterizing properties of virtual components. Through the monitoring, changes and change trends on the components are tracked and evaluated using the updated digital double dataset by calculations and/or by static and dynamic simulations.

Abstract: A customer communications device of a first network operator (H-MVNO) detects a network identifier from an access point of a second network (MNO) indicating that the second network provides access for first network devices in accordance with a sharing agreement. The device registers via the access point of the second network. Authentication and authorization for the device is performed by a first network security entity on behalf second network, with the device using a restricted use first IP address acquired from a DHCP in the second network. The home network (H-MVNO) sets up the session QoS from the home PCF and home SMF toward the visiting network SMF. The visiting network SMF executes the traffic QoS class via the visiting UPF with the device using a second IP address acquired from a DHCP in the second network for user plane data traffic through the second network.

Abstract: A deck box includes individual panels and a lid that are able to be assembled to one another without the need for external hardware. A bottom panel is connected to a pair of side panels. The side panels are provided with guides or rails that extend toward the bottom panel. Front and rear panels are provided with guides or rails so that each of the front and rear panel can assemble to and between the side panels, sliding into engagement in a direction toward the bottom panel. A lid has an integrally-molded hinge member that engages with an integrally-molded hinge member of the rear panel.

Abstract: An engineered stone product is made using a material that includes ceramic powder, glass sand, and a binder.

Abstract: Disclosed herein is a method for eccentricity correction. This method may dispose a downhole tool into a borehole. The downhole tool may comprise a measuring assembly that has at least one transducer, determining a beam pattern from the at least one transducer, determining a center of the measurement assembly in the borehole with the beam pattern, calculating a beam pattern factor with at least the beam pattern, calculating an angle factor with at least the beam pattern, calculating an eccentricity factor with at least the beam pattern factor and the angle factor, and creating an eccentricity corrected image with at least the eccentricity factor.

Abstract: A wireless network environment includes user equipment. A communication management resource in the user equipment establishes a wireless communication link between the user equipment and a first wireless station. The first wireless station provides the user equipment access to a remote network. Based on operating conditions of the user equipment, the communication management resource initiates execution of a paging notification retrieval function on the user equipment to retrieve paging notifications. Via the executed function (such as an application executed on the user equipment), and one or more request messages for paging notifications, the communication management resource communicates with a remote entity to retrieve the paging notifications.

Abstract: A content delivery network (CDN) includes UE gateways, a service switch (SS) mesh network, and server gateways. The CDN nodes maintain cache lists of mappings identifying corresponding upstream system nodes for content items available at content servers connected to the server gateways. When a CDN node receives an upstream service instance request for a specific content item by a corresponding UE connected to a UE gateway, upon determining that a mapping for the specific content item is in its cache list, the CDN node forwards the upstream service instance request to the corresponding upstream system node as part of a process of defining a downstream data path for the specific content item from the corresponding content server to the corresponding UE. The CDN enables service-level content delivery at lower levels of latency than conventional DNS-based systems.

Abstract: Various embodiments are directed to methods, apparatus, systems, architectures, mechanisms and apparatus providing a local, self-organizing, and automatic unlicensed channel(s) exclusion enforcement mechanism wherein a frequency coordination (AFC) function at a network device associated with an access point (AP), such as a home/business gateway including an AP.

Abstract: Based on a service agreement between a first wireless network provider and a content provider, a user, who subscribes to a second wireless network provider that does not have a roaming agreement with the first wireless network provider, can use an unauthenticated wireless device to receive content from a content system of the content provider via a wireless network of the first wireless network provider. In certain embodiments, the unauthenticated wireless device communicates with an orchestration node of the wireless network using encapsulated messages transmitted via a logical tunnel that bypass nodes of the wireless network that would otherwise prevent a network connection from being established between the unauthenticated wireless device and the wireless network.

Abstract: Lighting system including bowl reflector, visible-light source, central reflector, and optically-transparent body. Bowl reflector has central axis, and rim defining emission aperture, and first visible-light-reflective surface defining portion of cavity in bowl reflector. First visible-light-reflective surface includes parabolic surface. Visible-light source is located in cavity and configured for generating visible-light emissions from semiconductor light-emitting device. Central reflector includes second visible-light-reflective surface, having convex flared funnel shape and having first peak facing toward visible-light source. Optically-transparent body has first base being spaced apart from second base and having side wall extending between first and second bases. Concave flared funnel-shaped surface of second base faces toward convex flared funnel-shaped second visible-light reflective surface of central reflector.

Abstract: A method is disclosed, as well as systems, performed by one or more processors, for interacting with data in a data repository. The method comprises receiving, in a data catalogue environment, a search request relating to one or more items in the data repository and determining an object type associated with the one or more items. Other operations comprise loading an object template in dependence on the determined object type, populating the template with data from the data repository in dependence on the search request to create an object view, and displaying the object view within the data catalogue environment. The data repository comprises a plurality of joined datasets, and wherein the object view comprises one or more links to items in a joined dataset.

Abstract: A wireless network environment includes user equipment. A communication management resource in the user equipment establishes a wireless communication link between the user equipment and a first wireless station. The first wireless station provides the user equipment access to a remote network. Based on operating conditions of the user equipment, the communication management resource initiates execution of a paging notification retrieval function on the user equipment to retrieve paging notifications. Via the executed function (such as an application executed on the user equipment), and one or more request messages for paging notifications, the communication management resource communicates with a remote entity to retrieve the paging notifications.

Abstract: A method is disclosed, as well as systems, performed by one or more processors, for interacting with data in a data repository. The method comprises receiving, in a data catalogue environment, a search request relating to one or more items in the data repository and determining an object type associated with the one or more items. Other operations comprise loading an object template in dependence on the determined object type, populating the template with data from the data repository in dependence on the search request to create an object view, and displaying the object view within the data catalogue environment. The data repository comprises a plurality of joined datasets, and wherein the object view comprises one or more links to items in a joined dataset.