Patents by Inventor Richard Z. Lewanczuk

Richard Z. Lewanczuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
    Patent number: 5886012
    Abstract: Hypotensive mammals are treated to lower mean blood pressure by administering synergistic amounts of a calcium blocking agent together with a calcium supplement.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: March 23, 1999
    Assignee: Peter K. T. Pang
    Inventors: Peter K. T. Pang, Richard Z. Lewanczuk, Christine G. Benishin, Jie Shan
  • Active component of parathyroid hypertensive factor
    Patent number: 5739274
    Abstract: An active component of parathyroid hypertensive factor (PHF) which comprises a polypeptide linked to a phospholipid has been identified. The component has activities substantially similar to parathyroid hypertensive factor and therefore is indicated in the control of extracellular calcium uptake, and is related to hypertension and some other diseases in mammals. Method for screening patients for the presence of the circulating factor using antibodies against the component are described. Antagonists of the parathyroid hypertensive factor component have been developed and their use in methods of treating patients with diseases which involve intracellular calcium elevation are also described.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: April 14, 1998
    Assignee: CV Technologies, Inc.
    Inventors: Peter K. T. Pang, Christina G. Benishin, Shan Jie, Richard Z. Lewanczuk
  • Kit used in the treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
    Patent number: 5457132
    Abstract: A kit containing benzeneacetonitrile and calcium or dihydropyridine and calcium hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: October 10, 1995
    Assignee: Peter K. T. Pang
    Inventors: Peter K. T. Pang, Richard Z. Lewanczuk, Christine G. Benishin
  • Method of treatment for hypertension using combination therapy involving exogenous calcium and dihydropyridine calcium channel blockers
    Patent number: 5354765
    Abstract: Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.
    Type: Grant
    Filed: July 27, 1992
    Date of Patent: October 11, 1994
    Assignee: Peter K. T. Pang
    Inventors: Peter K. T. Pang, Richard Z. Lewanczuk, Christine G. Benishin
  • Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
    Patent number: 5350771
    Abstract: Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: September 27, 1994
    Assignee: Peter K. T. Pang
    Inventors: Peter K. T. Pang, Richard Z. Lewanczuk, Christine G. Benishin
  • Parathyroid hypertensive factor, antibodies and uses thereof
    Patent number: 5192664
    Abstract: A new circulating factor from the parathyroid gland of some hypertensive mammals have been isolated and characterized. Polyclonal and monoclonal antibodies raised against this factor are usable as a screen for the presence of the factor. The factor is involved in the control of calcium uptake in cells. Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly. The factor has a molecular weight of 3,000 to 4,000 Daltons.
    Type: Grant
    Filed: November 21, 1990
    Date of Patent: March 9, 1993
    Assignee: Peter K. T. Pang
    Inventors: Peter K. T. Pang, Richard Z. Lewanczuk, Christine G. Benishin, Toyoii Kaneko