Abstract: A prosthetic system for implantation between upper and lower vertebrae having an upper joint component and a lower joint component. The joint is adapted for implantation within a disc space between the upper and lower vertebrae, allowing the upper and lower vertebrae to move relative to one another. The system further includes a bridge component extending posteriorly from the lower joint component and from the disc space, with the bridge component having a lower contact surface configured for engaging a resected bone surface of a pedicle of the lower vertebrae. The distal end of the bridge component comprises a connection component adapted to receive a fastener.

Abstract: An ear cleaner is provided that includes an elongated handle, a spoon, and a disc intermediate the spoon and the disc.

Abstract: A method uses natural language for visual analysis of a dataset, and is performed at a computer having a display, processors, and memory. The computer displays a data visualization based on a dataset retrieved from a database and receives a first user input to specify a natural language command related to the displayed data visualization. Based on the displayed data visualization and the natural language command, the computer identifies an initial range of values for a first data field in the dataset and displays an editable user interface control showing the initial range of values. The computer receives a second user input, at the user interface control, specifying a modified range of values for the first data field and retrieves an updated dataset from the database using the modified range of values for the first data field. The computer then updates the displayed data visualization using the updated dataset.

Abstract: A metrology tool that includes a substrate table to hold a substrate; a projection system configured to project a beam on a target portion of the substrate; an actuator configured to adjust a position of the projection system relative to the substrate on the substrate table; a sensor configured to determine a position of the substrate table; and a one or more processors configured to: determine, based on the position of the substrate table, a position error of the substrate table with respect to a reference; and control, via the actuator, a position of the projection system to compensate for the position error of the substrate table so that the beam projects on the target portion of the substrate.

Abstract: The invention relates to the use of mavoglurant, or a pharmaceutically acceptable salt thereof: in the reduction of opioid use by an opioid use disorder patient; in preventing relapse into opioid use by an opioid use disorder patient; in the promotion of opioid abstinence by an opioid use disorder patient; in the treatment of the symptoms of depression or anxiety associated with opioid use disorder.

Abstract: A method for tracking an item in a distributed environment is provided. At least one node in a network adds a new block to a first cryptographically verifiable ledger represented by a first sequence of blocks that is stored in one or more non-transitory computer-readable media. The new block added to the first cryptographically verifiable ledger contains a component identifier and a hash of a previous block in the first sequence of blocks. The at least one node in the network adds a new block to a second cryptographically verifiable ledger represented by a second sequence of blocks that is stored in the one or more non-transitory computer-readable media. The new block added to the second cryptographically verifiable ledger contains a destination identifier, the first sequence of blocks, and a hash of a previous block in the second sequence of blocks.

Abstract: An apparatus includes a high side heat exchanger, a load, a compressor, a belt, a first bin, a second bin, and a controller. The high side heat exchanger removes heat from a refrigerant. The load uses the refrigerant to cool an enclosed space. The compressor compresses the refrigerant. The first and second bins are coupled to the belt and positioned within the enclosed space. The controller receives a first message, determines that the first bin should be selected, and cycles the belt to move the first bin to a retrieval location within the enclosed space. The controller also receives a second message, determines that the second bin should be selected, and cycles the belt to move the second bin to the retrieval location.

Abstract: The invention relates to the use of a mGluR5 antagonist for the treatment of opioid analgesic tolerance associated with chronic opioid use in chronic pain.

Abstract: An oral care device includes a body and a base connected to the body. The oral care device includes a mouthpiece extending from the base and an oral care product reservoir in communication with the mouthpiece. A plurality of brushing walls extend from the base about the mouthpiece.

Abstract: Disclosed is a laser discharge chamber in which useful lifetime is extended by local electrical tuning using one or a combination of design of the chamber internal geometry, placement and distribution of components within the chamber such as electrodes, current returns, and capacitors, and selective electrical isolation of portions of the components.

Abstract: A method uses natural language for visual analysis of a dataset, and is performed at a computer having a display, processors, and memory. The computer displays a data visualization based on a dataset retrieved from a database and receives a first user input to specify a natural language command related to the displayed data visualization. Based on the displayed data visualization and the natural language command, the computer identifies an initial range of values for a first data field in the dataset and displays an editable user interface control showing the initial range of values. The computer receives a second user input, at the user interface control, specifying a modified range of values for the first data field and retrieves an updated dataset from the database using the modified range of values for the first data field. The computer then updates the displayed data visualization using the updated dataset.

Abstract: In accordance with one aspect of the present disclosure, a fishing lure is provided that includes a body having an opening to receive a fish and at least one hook connected to the body. The body includes capture portions having a spaced apart, open configuration that permits fish to be positioned in the opening of the body and a closer, closed configuration wherein the capture portions capture the fish in the opening of the body.

Abstract: A method uses natural language for visual analysis of a dataset, and is performed at a computer having a display, processors, and memory. The computer displays a data visualization based on a dataset retrieved from a database and receives a first user input to specify a natural language command related to the displayed data visualization. Based on the displayed data visualization and the natural language command, the computer identifies an initial range of values for a first data field in the dataset and displays an editable user interface control showing the initial range of values. The computer receives a second user input, at the user interface control, specifying a modified range of values for the first data field and retrieves an updated dataset from the database using the modified range of values for the first data field. The computer then updates the displayed data visualization using the updated dataset.

Abstract: An adjustable depth fishing lure including a lip and a lure body is provided. The lip is partially received in a slot of the lure body and is movable to predetermined positions relative to the lure body. The lip may include an eyelet. The lip includes a locking member and the lure body includes a plurality of teeth. The locking member is configured to engage at least one of the teeth to fix the lip relative to the lure body at one of the predetermined positions. This engagement between the locking member and the teeth provides a rigid connection that resists loading applied to the lip by the fisherman pulling on the fishing line and/or a fish biting a hook connected to the lure body.

Abstract: A toothbrush device having a body defining a cavity and an input port disposed on the body in fluid communication with the cavity. The input port permits brushing by-products to pass through the input port and into the cavity while restricting passage of the brushing by-products outward from the cavity. In one form, the toothbrush device includes an elongated handle with a reservoir having at least a portion disposed within the handle. The reservoir is sized to hold a predetermined amount of oral care product, and a mouthpiece is in fluid communication with the reservoir to discharge the oral care product from the reservoir.

Abstract: An ear cleaning device is provided for removing debris from an ear. In one form, the ear cleaning device includes a shaft, a head connected to the shaft, and a contiguous pocket structure of the head. The contiguous pocket structure includes a plurality of pockets that may be configured to receive debris. In another form, the ear cleaning device has a handle, a bulbous cleaner connected to the handle, and a solid inner core of the bulbous cleaner. The bulbous cleaner has two or more spaced, longitudinal walls disposed outward of the inner core that are configured to remove debris with turning of the ear cleaning device about a longitudinal axis of the device.

Abstract: According to one embodiment, a prism system is provided. The prism system includes a polarizing beam splitter (PBS) surface. The PBS surface is configured to generate first and second sub-beams having corresponding first and second polarization information from a received beam, the second polarization information being different than the first polarization information. A first optical path of the first sub-beam within the prism system has substantially same length as a second optical path of the second sub-beam within the prism system. Additionally or alternatively, the first sub-beam achieves a predetermined polarization extinction ratio.