Abstract: The panelized roof sheathing construction system includes a plurality of panels attached to a building frame structure in substantially abutting relationship. Each panel includes a water resistant barrier layer secured atop the outward facing surface of the panel. The water resistant barrier layer includes a skid resistant surface. Joints between panels are sealed by strips of water resistant tape or the like. The panels are made of lignocellulosic material. The water resistant and skid resistant surface may include indicia for aligning strips of tape or for aligning fasteners.

Abstract: The panel includes a water resistant barrier layer secured atop its outward facing surface. The water resistant barrier layer includes a skid resistant surface. The panels are made of lignocellulosic material. The water resistant and skid resistant surface may include indicia for aligning strips of tape or for aligning fasteners. A method for manufacturing the water resistant building panels is also disclosed and includes the steps of feeding paper onto a forming belt, depositing lignocellulosic material and the binding agent onto the forming belt so as to form a lignocellulosic mat, applying heat and pressure so as to impart the skid resistant surface on the paper, and cutting panels to predetermined sizes.

Abstract: The invention comprises a wall sheathing barrier system having moisture permeability and simple improved installation method. The system comprises adjoined structural panels. Each panel has an overlay paper bonded permanently to the structural panel, which provides a moisture permeable barrier and a textured skid-resistant surface. The skid resistant surface may include indicia for aligning strips of tape or for aligning fasteners. Further, the seams of adjoining panels are sealed with a sealing means to complete the moisture barrier.

Abstract: The problem of inadequate and cost ineffective broad-range prognostic factors for breast cancer is solved by providing a method for constructing a cloning vector for preparing a multi-gene probe for a single-step determination of disease outcome. The 5-genes chosen (HER2, Topo II&agr;, NM23-H1, CK19 and MMP9) are known to show altered expression in different breast tumors. The multi-gene probe is labeled and used to screen a tumor specimen. Since five prognostic markers are prepared and used simultaneously, a wider variety of breast cancers may be covered and disease outcome prediction may be improved in a wider population at a substantially reduced cost.

Abstract: The problem of inadequate broad-range prognostic factors for breast cancer is solved by providing a multi-gene probe for a single-step determination of disease outcome. The 5-genes chosen (HER2, Topo II&agr;, NM23-H1, CK19 and MMP9) are known to show altered expression in different breast tumors. The altered expression of any one of them has a similar prognostic significance, with respect to disease-free survival or overall survival. The multi-gene probe is labeled and used to screen a tumor specimen. The signal generated after the assay provides information that has prognostic significance. Since five prognostic markers are simultaneously assessed, a wider variety of breast cancers are covered and disease outcome prediction is improved in a wider population.