Abstract: Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes providing a first set of data corresponding to a drug of interest: providing a disease signature; providing a reference set of drug interaction data associated with the disease signature, comparing the first set of data to the reference set using a holistic analysis, and reporting the results of the comparison. An example of the apparatus includes, a standardizer to at least one of standardize and normalize drug interaction data related to a pre-selected disease signature: a deviation analyzer to compare the drug interaction data to data corresponding to a drug under review using a holistic analysis, and a reporter for reporting the output of the deviation analyzer.

Abstract: Certain examples provide systems and methods for holistic viewing to provide comparative analysis and patient treatment decision support in a drug therapy development process. A computer-implemented method for developing a therapeutic drug treatment plan for a patient using quantifiable comparative holistic decision support. In addition, the inventive may also be summarized as a computer-implemented method for developing a therapeutic drug treatment plan for a patient using quantifiable comparative holistic decision support for a known disease signature corresponding to a subject medical condition of a patient.

Abstract: Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example of the inventive apparatus includes a standardizer to at least one of standardize and normalize data related to drug performance for a known disease signature; and a deviation analyzer to analyze said data based on at least one of a plurality of different efficacy metrics, wherein a quantified variation between a first data set of results corresponding to an identified target drug and a second data set of results corresponding to a control, wherein said first data set of results is provided for comparison with the second data set of results and the deviation therebetween is compared to the at least one efficacy metric associated with the disease signature.

Abstract: Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. A computer-implemented method for integrated comparative holistic analysis of drug development and related quantifiable patient treatment decision support for a medical condition having a known disease signature.

Abstract: An apparatus and method for determining the biological amplitude and frequency windows of magnetic fields. The method for determining the biological window for the field metrics of a magnetic field is described with particular reference to a chemical system and method using myosin light chain kinase, calmodulin, and magnetic fields. The process is designed to calculate and measure the number of radioactive events (i.e., Cherenkov emissions) of a specimen or sample wherein such events are indicative of the relative biological effectiveness as will be described herein below.

Abstract: A method and apparatus for relieving pain associated with degenerative diseases and disorders in biological subjects such as mammals. The method employs the use of an apparatus which is capable of producing a magnetic field of a particular nature which has been proven in human tests to dramatically reduce pain. An embodiment of the apparatus includes a frame, a plurality of magnets capable of producing a magnetic field wherein each of the plurality of magnets has a north pole and a south pole and a longitudinal axis passing therethrough and are partially held in place by the frame. Another embodiment incorporates a coil of electrically conducting material is wrapped about a frame, and/or the plurality of magnets in an orthogonal relationship to the longitudinal axis of each of the plurality of magnets. A source of electrical energy supplies an electrical current to the coil enabling a magnetic field to be produced therefrom.

Abstract: A method and apparatus for relieving pain associated with degenerative diseases and disorders in biological subjects such as mammals. The method employs the use of an apparatus which is capable of producing a magnetic field of a particular nature which has been proven in human tests to dramatically reduce pain. An embodiment of the apparatus includes a frame, a plurality of magnets capable of producing a magnetic field wherein each of the plurality of magnets has a north pole and a south pole and a longitudinal axis passing therethrough and are partially held in place by the frame. Another embodiment incorporates a coil of electrically conducting material is wrapped about a frame, and/or the plurality of magnets in an orthogonal relationship to the longitudinal axis of each of the plurality of magnets. A source of electrical energy supplies an electrical current to the coil enabling a magnetic field to be produced therefrom.

Abstract: A magnetic field device and method for inhibiting angiogenesis and retarding growth rates of cancerous tumors present in mammals. The apparatus includes a frame, and a wire consisting of electrically conducting material. The wire is wrapped around the frame to form a coil. A source of AC current is connected to a transformer to vary the AC voltage. The AC current is passed through a bridge rectifier and then to the coil of wire enabling a DC rectified wave magnetic field to be produced therefrom. The method employs the use of an apparatus which is capable of producing a magnetic field of a particular nature which has been proven in animal studies to affect angiogenesis and retard the growth rate of cancerous tumors.

Abstract: A method and apparatus for affecting angiogenesis in biological subjects such as mammals. The method employs the use of an apparatus which is capable of producing a magnetic field of a particular nature which has been proven in animal studies to affect angiogenesis. The apparatus includes a frame, a plurality of magnets capable of producing a magnetic field wherein each of the plurality of magnets has a north pole and a south pole and a longitudinal axis passing therethrough and are partially held in place by the frame. A coil of electrically conducting material is wrapped about the plurality of magnets in an orthogonal relationship to the longitudinal axis of each of the plurality of magnets. A source of electrical energy supplies an electrical current to the coil enabling a magnetic field to be produced therefrom. A switch is provided to enable the electrical current to flow in a first direction and optionally in a second direction opposite to the first direction.

Abstract: A slip on recoil pad having a sleeve portion and a cushion portion. The sleeve and cushion portions can be formed integral with one another or be separate components attached together. The sleeve component may be comprised of a neoprene or polypropylene rubber for providing enhanced cushioning, warmth, and durability, and may also include a rifle sling attachment stud, grommet. The rifle sling attachment stud preferably includes a reinforcing liner or strip to prevent the reinforcing stud from pulling through the sleeve portion of the recoil pad. In addition, a protective layer is provided to overlie the rivet, or grommet portion attached to the eyelet of the rifle sling attachment stud to prevent marring or scratching of the rifle stock when it is installed and attached thereto.

Abstract: The present invention is directed to a laser assisted telescopic targeting system, apparatus and method of range finding and aiming a projectile firing weapon. The invention includes a laser light generating source capable of producing a spot of laser light on a target. The invention also includes a shooting scope to view the target. The shooting scope preferably has indicia or a shutter for measuring the approximate size of the laser dot projected on the target. Based upon the size of the spot and the growth rate of the laser targeting source the user can determine, with a substantial degree of accuracy, the relative distance from the target. The method includes steps associated with using the inventive apparatus and system and aiming a projectile firing weapon depending upon the information obtained.

Abstract: The present invention is directed to an apparatus and method for magnetically filtering metallic particulates from lubricating fluids or oils used in motorized vehicles. The invention includes a magnet and an optional sleeve. The sleeve holds the magnet and is configured for overlying the canister of a canister type oil filter. The sleeve is preferably made from a high temperature resistant material to withstand the heat associated with the operating temperature of the oil within filter. The invention is also directed to a magnetically assisted oil filter having a magnet incorporated into the canister.