Abstract: An orthopedic stocking, comprising a tubular elastic sheath having closed ends and formed with a fenestration adjacent a first of said ends. The stocking is folded in a manner such that the second closed end is drawn through the sheath and projects through the fenestration in the first end to provide overlapping sections. The overlapping sections are then reverse folded to form an outer cuff disposed outwardly of the overlapping sections. To apply the stocking to an extremity, such as a leg, the toe is inserted into the closed second that projects through the fenestration, and the cuff is unrolled upwardly along the limb. After the cuff is unrolled, the corners or ears of the first end are grasped and pulled upwardly to roll the stocking along the limb and the fenestration is sealed to the limb. The stocking provides a sterile seal to the limb to prevent cross contamination.