Patents by Inventor Ricky L. Fenton

Ricky L. Fenton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of 10-keto morphinans by benzylic oxidation
    Patent number: 8314237
    Abstract: The present invention provides processes for the preparation of 10-keto and/or 10-hydroxy morphinans. In particular, the invention provides to processes for preparing a 10-keto morphinan by chromium-catalyzed benzylic oxidation of a morphinan with a periodic acid.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: November 20, 2012
    Assignee: Mallinckrodt LLC
    Inventors: Hang Sun, John E. Johnson, Jr., Ricky L. Fenton, Sarah M. Dorn
  • Preparation of 10-Keto Morphinans by Benzylic Oxidation
    Publication number: 20110071296
    Abstract: The present invention provides processes for the preparation of 10-keto and/or 10-hydroxy morphinans. In particular, the invention provides to processes for preparing a 10-keto morphinan by chromium-catalyzed benzylic oxidation of a morphinan with a periodic acid.
    Type: Application
    Filed: September 7, 2010
    Publication date: March 24, 2011
    Applicant: Mallinckrodt Inc.
    Inventors: Hang Sun, John E. Johnson, JR., Ricky L. Fenton, Sarah M. Dorn
  • Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
    Patent number: 6908919
    Abstract: The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: June 21, 2005
    Assignee: Pharmacia Corporation
    Inventors: Michael S. South, Brenda L. Case, Thomas A. Dice, Ricky L. Fenton, Gary W. Franklin, Michael J. Hayes, Horng-Chih Huang, Wei Huang, Darin E. Jones, Carrie L. Kusturin, Richard J. Lindmark, Scott A. Long, William L. Neumann, David B. Reitz, John I. Trujillo, Ching-Cheng Wang, Rhonda Wood, Qingping Zeng, Matthew W. Mahoney, John J. Parlow, Melvin L. Rueppel
  • 6-Membered unsaturated heterocyclic compounds useful for selective inhibition of the coagulation cascade
    Publication number: 20040106626
    Abstract: The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
    Type: Application
    Filed: October 3, 2002
    Publication date: June 3, 2004
    Applicant: Pharmacia Corporation
    Inventors: Michael S. South, Ronald K. Webber, Horng-Chih Huang, Mihaly V. Toth, Alan E. Moormann, Jeffery S. Snyder, Jeffrey A. Scholten, Danny J. Garland, Melvin L. Rueppel, William L. Neumann, Scott Long, Wei Huang, John Trujillo, John J. Parlow, Darin E. Jones, Brenda Case, Michael J. Hayes, Qingping Zeng, Ricky L. Fenton, Carrie L. Kusturin, Hayat K. Rahman, Zaheer Abbas, Kirby R. Sample, Barbara A. Schweitzer, Rhonda S. Wood, Jim Szalony, Osman D. Suleymanov, Anita Salyers, Nancy S. Nicholson
  • Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
    Publication number: 20040006230
    Abstract: The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Application
    Filed: July 15, 2002
    Publication date: January 8, 2004
    Applicant: Pharmacia Corporation
    Inventors: Michael S. South, Brenda L. Case, Thomas A. Dice, Ricky L. Fenton, Gary W. Franklin, Michael J. Hayes, Horng-Chih Huang, Wei Huang, Darin E. Jones, Carrie L. Kusturin, Richard J. Lindmark, Scott A. Long, William L. Neumann, David B. Reitz, John I. Trujillo, Ching-Cheng Wang, Rhonda Wood, Qingping Zeng, Matthew W. Mahoney, John J. Parlow, Melvin L. Rueppel
  • Ph-selective delivery system using crosslinked polymeric resins as vehicles
    Patent number: 6471955
    Abstract: This invention provides a method of preparing a polymeric delivery system for active ingredients having enhanced site specific release performance characteristics. The delivery system is formed either by attaching the active ingredient to a linker through an acid-sensitive covalent bond, then forming a covalent bond between the linker and a portion of the subunits of a crosslinked polystyrene polymer, or by attaching a linker to a portion of the subunits of a crosslinked polystyrene polymer, then attaching the active ingredient to the polymer-linker combination through an acid-sensitive covalent bond. The invention also provides a delivery system comprising an active ingredient covalently bonded through an acid-sensitive covalent bond to a linker, which is in turn covalently bonded to a portion of subunits of a crosslinked polystyrene polymer.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: October 29, 2002
    Assignee: Pharmacia Corporation
    Inventors: Samuel J. Tremont, Denis Forster, Ricky L. Fenton, Yinong Ma
  • Gastro-specific prodrugs
    Patent number: 6413945
    Abstract: A compound is disclosed havin the formula AW—SiR1R2R3 wherein R1 and R2 are independently alkyl, cycloalkyl, alkenyl, alkynyl, aryl, aralkyl, alkaryl, or a hydrophilic group; R3 is a hydrophilic group; and AW is the covalently bonded form of a drug AWH, wherein W is O, NH, S, or an enolate group. The hydrophilic group may be either non-neutral, or may be a polyol. This compound serves as a prodrug for the drug AWH. A method for preparing these compounds is also disclosed. Also disclosed is a method of treatment or prevention of gastric ulcers by administering the prodrug compounds.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: July 2, 2002
    Assignee: Pharmacia Corporation
    Inventors: Samuel J. Tremont, Paul W. Collins, Ricky L. Fenton