Abstract: An oil circulation device for an internal combustion engine includes an oil pan, a partition, and a communication groove. The oil pan is disposed below a cylinder block and includes a bottom wall and a sidewall to define a recessed portion that opens upward. The partition extends upward from the bottom wall so as to have a protruding end and divide the recessed portion into a first recessed portion and a second recessed portion. The communication groove extends downward from the protruding end of the partition in a thickness direction of the partition to connect the first recessed portion and the second recessed portion.

Abstract: An oil circulation device for an internal combustion engine includes an oil pan, a partition, and a communication groove. The oil pan is disposed below a cylinder block and includes a bottom wall and a sidewall to define a recessed portion that opens upward. The partition extends upward from the bottom wall so as to have a protruding end and divide the recessed portion into a first recessed portion and a second recessed portion. The communication groove extends downward from the protruding end of the partition in a thickness direction of the partition to connect the first recessed portion and the second recessed portion.

Abstract: To overcome disadvantages of a known creatinine amide hydrolase, and provide a creatinine amide hydrolase having improved affinity for creatinine or having a decreased Km value for creatinine, and also provide a reagent composition for use in the determination of creatinine, which is adapted to an automated analysis apparatus and is excellent in accuracy, preciseness and economic efficiency. Disclosed is a modified creatinine amide hydrolase having improved affinity for a substrate compared to an unmodified one. Also disclosed is a creatinine determination reagent comprising the modified creatinine amide hydrolase, a creatinine amidino hydrolase, sarcosine oxidase and a reagent for detection of hydrogen peroxide.

Abstract: [Problems] To overcome disadvantages of a known creatinine amide hydrolase, and provide a creatinine amide hydrolase having improved affinity for creatinine or having a decreased Km value for creatinine, and also provide a reagent composition for use in the determination of creatinine, which is adapted to an automated analysis apparatus and is excellent in accuracy, preciseness and economic efficiency. [Means for Solving Problems] Disclosed is a modified creatinine amide hydrolase having improved affinity for a substrate compared to an unmodified one. Also disclosed is a creatinine determination reagent comprising the modified creatinine amide hydrolase, a creatinine amidino hydrolase, sarcosine oxidase and a reagent for detection of hydrogen peroxide.