Patents by Inventor Rie Tokizane

Rie Tokizane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tau aggregation inhibitor
    Patent number: 9907799
    Abstract: A tau aggregation inhibitor can sufficiently inhibit a tau protein from aggregating in cells. The inhibitor includes a 4-substituted catechol structure compound, having, at position 4 of its catechol ring, an electron-donating substituent R other than a hydrocarbon group, or a salt thereof. The 4-substituted catechol structure compound is preferably 4-aminocatechol or 1,2,4-benzenetriol. Examples of tauopathies to which this inhibitor is applicable include AD, Down's syndrome, frontotemporal dementia, cotricobasal degeneration (CBD) and progressive supranuclear palsy (PSP).
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: March 6, 2018
    Assignees: THE DOSHISHA, National Center for Geriatrics and Gerontology
    Inventors: Tomohiro Miyasaka, Hachiro Sugimoto, Rie Tokizane, Yuki Shinzaki, Yohei Oe, Tetsuo Ota, Akihiko Takashima, Yoshiyuki Soeda, Yasuo Ihara, Yoshikazu Inoue
  • Pyrazole derivative
    Patent number: 9724333
    Abstract: Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): or a salt thereof.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: August 8, 2017
    Assignee: GREEN TECH CO., LTD.
    Inventors: Hachiro Sugimoto, Michiaki Okuda, Shinichi Nakayama, Yoshikazu Inoue, Yoko Sakata, Yuki Fujita, Rie Tokizane
  • NOVEL PYRAZOLE DERIVATIVE
    Publication number: 20160228412
    Abstract: Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): or a salt thereof.
    Type: Application
    Filed: April 19, 2016
    Publication date: August 11, 2016
    Inventors: Hachiro Sugimoto, Michiaki Okuda, Shinichi Nakayama, Yoshikazu Inoue, Yoko Sakata, Yuki Fujita, Rie Tokizane
  • Pyrazole derivative
    Patent number: 9321752
    Abstract: Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): or a salt thereof.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: April 26, 2016
    Assignee: GREEN TECH CO., LTD.
    Inventors: Hachiro Sugimoto, Michiaki Okuda, Shinichi Nakayama, Yoshikazu Inoue, Yoko Sakata, Yuki Fujita, Rie Tokizane
  • TAU AGGREGATION INHIBITOR
    Publication number: 20160030437
    Abstract: A tau aggregation inhibitor can sufficiently inhibit a tau protein from aggregating in cells. The inhibitor includes a 4-substituted catechol structure compound, having, at position 4 of its catechol ring, an electron-donating substituent R other than a hydrocarbon group, or a salt thereof. The 4-substituted catechol structure compound is preferably 4-aminocatechol or 1,2,4-benzenetriol. Examples of tauopathies to which this inhibitor is applicable include AD, Down's syndrome, frontotemporal dementia, cotricobasal degeneration (CBD) and progressive supranuclear palsy (PSP).
    Type: Application
    Filed: April 2, 2014
    Publication date: February 4, 2016
    Inventors: Tomohiro Miyasaka, Hachiro Sugimoto, Rie Tokizane, Yuki Shinzaki, Yohei Oe, Tetsuo Ota, Akihiko Takashima, Yoshiyuki Soeda, Yasuo Ihara, Yoshikazu Inoue
  • Novel Pyrazole Derivative
    Publication number: 20150252029
    Abstract: Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): or a salt thereof.
    Type: Application
    Filed: September 17, 2013
    Publication date: September 10, 2015
    Inventors: Hachiro Sugimoto, Michiaki Okuda, Shinichi Nakayama, Yoshikazu Inoue, Yoko Sakata, Yuki Fujita, Rie Tokizane