Patents by Inventor Rienk Henrik Kuipers

Rienk Henrik Kuipers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a beta -lactam nucleus and the application thereof
    Publication number: 20040053912
    Abstract: The invention relates to a process for the preparation of an aqueous solution or suspension of a &bgr;-lactam nucleus and application thereof. The aqueous solution or suspension of the &bgr;-lactam nucleus is prepared by process wherein an enzymatic deacylation of a &bgr;-lactam compound, which compounds comprises a &bgr;-lactam nucleus with a side chain coupled to it via an amide bond and which deacylation reaction is carried out in a mixture of water and an organic solvent and which deacylation leads to a &bgr;-lactam nucleus and a carboxylic acid, is carried out at a pH value of between 2 and 6 so that the carboxylic acid is extracted in situ to the organic solvent.
    Type: Application
    Filed: September 29, 2003
    Publication date: March 18, 2004
    Inventors: Thomas van der Does, Rienk Henrik Kuipers, Marjon Brigitte Diender, Jeroen Leonardus den Hollander, Adrianus Johannes Jozef Straathof, Lucas Antonius Maria van der Wielen, Joseph Johannes Heijnen