Abstract: A microfluidic chip pump is provided. The microfluidic chip pump may include: a pump housing comprising a pump cavity, a moveable member arranged in the pump cavity, separating the pump cavity into a first chamber and a second chamber; and an actuator assembly configured to drive the moveable member between a first stable position and a second stable position, changing a volume of the first chamber and a volume of the second chamber. When the moveable member is at the first stable position, the first chamber may reach a minimum volume. When the moveable member is at the second stable position, the first chamber may reach a maximum volume. The microfluidic chip pump may be configured to expel a fixed volume of fluid from the second chamber each time the moveable member is driven from the first stable position to the second stable position.

Abstract: A microfluidic chip pump is provided. The microfluidic chip pump may include: a pump housing comprising a pump cavity, a moveable member arranged in the pump cavity, separating the pump cavity into a first chamber and a second chamber; and an actuator assembly configured to drive the moveable member between a first stable position and a second stable position, changing a volume of the first chamber and a volume of the second chamber. When the moveable member is at the first stable position, the first chamber may reach a minimum volume. When the moveable member is at the second stable position, the first chamber may reach a maximum volume. The microfluidic chip pump may be configured to expel a fixed volume of fluid from the second chamber each time the moveable member is driven from the first stable position to the second stable position.

Abstract: A microfluidic chip for circulating tumor cell separation, comprising a first shell layer, a second shell layer, and a filter membrane between the first shell layer and the second shell layer. A first channel is formed between the filter membrane and the first shell layer; a second channel is formed between the filter membrane and the second shell layer; the first shell layer is provided with m input interfaces and n output interfaces, wherein m is greater than or equal to 1 and n is greater than or equal to 1; the second shell layer is provided with x input interfaces and y output interfaces, wherein x is greater than or equal to 1 and y is greater than or equal to 1. The chip is used for circulating tumor cell separation to achieve high flux, high efficiency, and a simple method, and facilitate promotion.