Patents by Inventor Riley Brien

Riley Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for whole cell analysis
    Patent number: 11426729
    Abstract: The present disclosure relates to systems and methods for whole cell analysis. In particular, the present disclosure relates to single cell genomic analysis (e.g., gene expression analysis.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: August 30, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Euisik Yoon, Yu-Heng Cheng, Yu-Chih Chen, Riley Brien, Max S. Wicha
  • Droplet actuator and methods of droplet manipulation
    Patent number: 10525472
    Abstract: Apparatus, methods, and systems for automated liquid droplet manipulation include an open droplet supporting surface. An actuator can translate the surface in space with at least one degree freedom of movement to influence movement of one or more droplets on the surface. In one embodiment, the surface is patterned with areas that attract the droplets and interstitial areas that repel the droplets to enhance transport of droplets. For example, for water-based droplets the attracting areas can be hydrophilic and the repelling hydrophobic. In one embodiment, the repelling areas are superhydrophobic. Electromechanical movement of the surface avoids expensive and complex microfluidic fabrication and components, and avoids electrowetting requirements.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: January 7, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Santosh Pandey, Riley Brien, Taejoon Kong, Zach Njus, Jared Anderson
  • SYSTEMS AND METHODS FOR WHOLE CELL ANALYSIS
    Publication number: 20190344270
    Abstract: The present disclosure relates to systems and methods for whole cell analysis. In particular, the present disclosure relates to single cell genomic analysis (e.g., gene expression analysis.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 14, 2019
    Inventors: Euisik Yoon, Yu-Heng Cheng, Yu-Chih Chen, Riley Brien, Max S. Wicha