Patents by Inventor Rimantas Slibinskas

Rimantas Slibinskas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calreticulin for Treating or Preventing an Angiogenic Eye Disease
    Publication number: 20220370554
    Abstract: The present invention relates to therapeutic use of calreticulin in treatment of angiogenic eye diseases. Different treatment methods and pharmaceutical compositions comprising calreticulin are disclosed.
    Type: Application
    Filed: October 7, 2020
    Publication date: November 24, 2022
    Applicant: UAB BALTYMAS
    Inventors: Rimantas Slibinskas, Evaldas Ciplys
  • Generation of native recombinant secreted human endoplasmic reticulum chaperones by using their native signal sequences in yeast expression systems
    Patent number: 9796971
    Abstract: A method using yeast as a host for production of human ER chaperone proteins, using endogenous signal peptides of intracellular human proteins that are recognized and correctly processed in the yeast cells to subsequently lead to the secretion of the human proteins. The resultant proteins possessed native amino acid sequence and were biologically active. Moreover, secretion allowed simple one-step purification of native recombinant human proteins with high yields.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 24, 2017
    Assignee: UAB BALTYMAS
    Inventors: Evaldas Ciplys, Rimantas Slibinskas, Kestutis Sasnauskas, Marek Michalak, Leslie Ina Gold
  • Generation of Native Recombinant Secreted Human Endoplasmic Reticulum Chaperones by Using Their Native Signal Sequences in Yeast Expression Systems
    Publication number: 20150191713
    Abstract: A method using yeast as a host for production of human ER chaperone proteins, using endogenous signal peptides of intracellular human proteins that are recognized and correctly processed in the yeast cells to subsequently lead to the secretion of the human proteins. The resultant proteins possessed native amino acid sequence and were biologically active. Moreover, secretion allowed simple one-step purification of native recombinant human proteins with high yields.
    Type: Application
    Filed: January 12, 2015
    Publication date: July 9, 2015
    Applicant: UAB BALTYMAS
    Inventors: Evaldas Ciplys, Rimantas Slibinskas, Kestutis Sasnauskas, Marek Michalak, Leslie Ina Gold