Abstract: The proposed medicinal preparation comprises a filler and an active principle which is hydrazide of diphenylphosphinylacetic acid of the formula: ##STR1## The filler may be starch and calcium stearate. The preparation is administered in the form of pills containing about 83 percent by weight of the active principle.The preparation of this invention is advantageous over the existing preparations used for treating neurotic and psychic disorders with pronounced vegetative disturbances in that it has a greater regulating effect on vegetative disturbances. The proposed preparation is the most effective for treating temporal lobe epilepsy with psychosensory, psychomotor, emotional and vegetative paroxysms.The preparation is well endured by patients. It produces no complications, nor side effects and can be used over prolonged periods of time for treating both young and old patients.

Abstract: The process according to the present invention comprises reacting diphenylchlorophosphine with ethylene oxide in a medium of an inert organic solvent. The resulting reaction mixture is heated in the presence of an alkyl ester of a haloacetic acid until the formation of an alkyl ester of diphenylphosphinylacetic acid. The latter, without separation and any additional purification, is reacted with hydrazine hydrate. The advantage of the process according to the present invention resides in a simplified technology, preparation of the desired product in a single stage at a high yield and the use of readily available commercially produced reagents.