Patents by Inventor Rina AOKI

Rina AOKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018562
    Abstract: A cyclic lipopeptide-producing microbial strain improve productivity of a cyclic lipopeptide, such as surfactin, via microbial culture. The cyclic lipopeptide-producing microbial strain, lack at least one of a gene encoding betaine aldehyde dehydrogenase (EC:1.2.1.8) or a gene encoding choline dehydrogenase (EC:1.1.1.1), and a method for producing a cyclic lipopeptide comprising culturing such microbial strain are provided.
    Type: Application
    Filed: August 21, 2023
    Publication date: January 18, 2024
    Applicant: KANEKA CORPORATION
    Inventors: Rina Aoki, Shingo Kobayashi, Naoaki Taoka
  • Patent number: 11268113
    Abstract: Provided are a PHA-producing microorganism producing a higher molecular weight PHA and a PHA production method using the PHA-producing microorganism. A PHA-producing microorganism including a gene encoding a PHA synthase derived from genus Aeromonas, in which at least a portion of a PHA degrading enzyme gene is altered by substitution, deletion, insertion, and/or addition to reduce or eliminate activity of a PHA degrading enzyme encoded by the gene, and further a glycerol kinase activity is enhanced.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: March 8, 2022
    Assignee: KANEKA CORPORATION
    Inventors: Rina Aoki, Shunsuke Sato
  • Patent number: 11225676
    Abstract: A PHA copolymer which is slowly crystallized is improved in crystallization speed to improve the melt workability of the PHA copolymer in working such as injection molding, film molding, blow molding, fiber spinning, extrusion foaming or bead foaming, thereby improving the resultant articles in productivity. A method for the improvement is a method for producing a PHA mixture, including the step of culturing a microorganism having both of a gene encoding a PHA synthase that synthesizes a copolymer PHA (A) and that is derived from the genus Aeromonas, and a gene encoding a PHA synthase that synthesizes a PHA (B) different in melting point from the copolymer PHA (A) by 10° C. or more to produce, in a cell of the microorganism, two or more PHAs different in melting point from one another by 10° C. or more simultaneously.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: January 18, 2022
    Assignee: KANEKA CORPORATION
    Inventors: Shingo Kobayashi, Rina Aoki, Tetsuya Minami, Hisashi Arikawa, Keiji Matsumoto
  • Patent number: 10876140
    Abstract: Provided is a method for producing PHA by a microbe with improved productivity of PHA, and a PHA-producing microbe used for the production method. A method for producing polyhydroxyalkanoic acid, the method including a step of culturing a microbe having a polyhydroxyalkanoic acid synthase gene and an inactivated gene encoding a flagellar protein to cause the microbe to produce polyhydroxyalkanoic acid. In the microbe, a lipase, a dephosphorylating enzyme, and a protein represented by the amino acid sequence of SEQ ID NO: 6 or 7 may be additionally inactivated. The microbe may be Cupriavidus necator.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: December 29, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Shunsuke Sato, Hisashi Arikawa, Rina Aoki
  • Publication number: 20200109423
    Abstract: Provided is a method for producing PHA by a microbe with improved productivity of PHA, and a PHA-producing microbe used for the production method. A method for producing polyhydroxyalkanoic acid, the method including a step of culturing a microbe having a polyhydroxyalkanoic acid synthase gene and an inactivated gene encoding a flagellar protein to cause the microbe to produce polyhydroxyalkanoic acid. In the microbe, a lipase, a dephosphorylating enzyme, and a protein represented by the amino acid sequence of SEQ ID NO: 6 or 7 may be additionally inactivated. The microbe may be Cupriavidus necator.
    Type: Application
    Filed: December 20, 2017
    Publication date: April 9, 2020
    Applicant: KANEKA CORPORATION
    Inventors: Shunsuke SATO, Hisashi ARIKAWA, Rina AOKI
  • Publication number: 20200087687
    Abstract: Provided are a PHA-producing microorganism producing a higher molecular weight PHA and a PHA production method using the PHA-producing microorganism. A PHA-producing microorganism including a gene encoding a PHA synthetase derived from genus Aeromonas, in which at least a portion of a PHA degrading enzyme gene is altered by substitution, deletion, insertion, and/or addition to reduce or eliminate activity of a PHA degrading enzyme encoded by the gene, and further a glycerol kinase activity is enhanced.
    Type: Application
    Filed: May 23, 2018
    Publication date: March 19, 2020
    Applicant: KANEKA CORPORATION
    Inventors: Rina AOKI, Shunsuke SATO
  • Publication number: 20200056214
    Abstract: A PHA copolymer which is slowly crystallized is improved in crystallization speed to improve the melt workability of the PHA copolymer in working such as injection molding, film molding, blow molding, fiber spinning, extrusion foaming or bead foaming, thereby improving the resultant articles in productivity. A method for the improvement is a method for producing a PHA mixture, including the step of culturing a microorganism having both of a gene encoding a PHA synthase that synthesizes a copolymer PHA (A) and that is derived from the genus Aeromonas, and a gene encoding a PHA synthase that synthesizes a PHA (B) different in melting point from the copolymer PHA (A) by 10° C. or more to produce, in a cell of the microorganism, two or more PHAs different in melting point from one another by 10° C. or more simultaneously.
    Type: Application
    Filed: October 31, 2019
    Publication date: February 20, 2020
    Applicant: KANEKA CORPORATION
    Inventors: Shingo KOBAYASHI, Rina AOKI, Tetsuya MINAMI, Hisashi ARIKAWA, Keiji MATSUMOTO
  • Patent number: 10519473
    Abstract: A PHA copolymer which is slowly crystallized is improved in crystallization speed to improve the melt workability of the PHA copolymer in working such as injection molding, film molding, blow molding, fiber spinning, extrusion foaming or bead foaming, thereby improving the resultant articles in productivity. A method for the improvement is a method for producing a PHA mixture, including the step of culturing a microorganism having both of a gene encoding a PHA synthase that synthesizes a copolymer PHA (A) and that is derived from the genus Aeromonas, and a gene encoding a PHA synthase that synthesizes a PHA (B) different in melting point from the copolymer PHA (A) by 10° C. or more to produce, in a cell of the microorganism, two or more PHAs different in melting point from one another by 10° C. or more simultaneously.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: December 31, 2019
    Assignee: KANEKA CORPORATION
    Inventors: Shingo Kobayashi, Rina Aoki, Tetsuya Minami, Hisashi Arikawa, Keiji Matsumoto
  • Publication number: 20170198313
    Abstract: A PHA copolymer which is slowly crystallized is improved in crystallization speed to improve the melt workability of the PHA copolymer in working such as injection molding, film molding, blow molding, fiber spinning, extrusion foaming or bead foaming, thereby improving the resultant articles in productivity. A method for the improvement is a method for producing a PHA mixture, including the step of culturing a microorganism having both of a gene encoding a PHA synthase that synthesizes a copolymer PHA (A) and that is derived from the genus Aeromonas, and a gene encoding a PHA synthase that synthesizes a PHA (B) different in melting point from the copolymer PHA (A) by 10° C. or more to produce, in a cell of the microorganism, two or more PHAs different in melting point from one another by 10° C. or more simultaneously.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 13, 2017
    Applicant: KANEKA CORPORATION
    Inventors: Shingo KOBAYASHI, Rina AOKI, Tetsuya MINAMI, Hisashi ARIKAWA, Keiji MATSUMOTO
  • Publication number: 20170198136
    Abstract: The purpose of the present invention is to improve processability in the melt-molding by improving the slowness of crystallization that is a disadvantage of polyhydroxyalkanoate, which is slow to crystallize, and to improve processing speed. Provided is a polyester resin composition including a first polyhydroxyalkanoate and a second polyhydroxyalkanoate, wherein the melting point of the second polyhydroxyalkanoate in the polyester resin composition is observed at a temperature lower than the melting point measured for the second polyhydroxyalkanoate alone.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 13, 2017
    Applicant: KANEKA CORPORATION
    Inventors: Tetsuya MINAMI, Shingo KOBAYASHI, Rina AOKI, Noriyuki SUZUKI