Patents by Inventor Rina Ulmansky

Rina Ulmansky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B-cell epitope peptides of HSP 65, novel amino acid sequences, DNA encoding the amino acid sequences of said peptides, antibodies directed against said peptides and different uses thereof in the treatment of inflammatory and autoimmune diseases
    Patent number: 8158125
    Abstract: B-cell epitope peptides of HSP 65, particularly the peptides comprising the amino acid sequence substantially as denoted by SEQ ID: NOs. 1-5 and their biologically functional homologues and derivatives thereof. Also included are polyclonal and monoclonal antibodies directed against them and their compositions for passive immunization against inflammatory and autoimmune diseases and in the treatment of inflammatory and autoimmune diseases. Also encompassed are diagnostic uses of these antibodies, for identifying people at risk of developing arthritis or diabetes, and a method of monitoring progress of the disease conditions and disease prognosis.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: April 17, 2012
    Assignee: Hadasit Medical Research Services & Development Ltd.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkei Kashi
  • Use of liposomal glucocorticoids for treating inflammatory states
    Patent number: 7744920
    Abstract: The present invention provides the use of a glucocorticoid (GC) or of a GC derivative encapsulated in a liposome for the preparation of a pharmaceutical composition for the treatment of an inflammatory associated condition in a subject, provided that said condition is not associated with a neurodegenerative disease or disorder. A specific use concerns a liposomal formulation comprising methylprednisolone sodium hemisuccinate (MPS) for the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: September 11, 2005
    Date of Patent: June 29, 2010
    Assignees: Hadasit Medical Research Services & Development Limited, Yissum Research Development Company of the Hebrew University
    Inventors: Yechezkel Barenholz, Yaakov Naparstek, Yuval Avnir, Rina Ulmansky
  • B-CELL EPITOPE PEPTIDES OF HSP 65, NOVEL AMINO ACID SEQUENCES, DNA ENCODING THE AMINO ACID SEQUENCES OF SAID PEPTIDES, ANTIBODIES DIRECTED AGAINST SAID PEPTIDES AND DIFFERENT USES THEREOF IN THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES
    Publication number: 20090181028
    Abstract: B-cell epitope peptides of HSP 65, particularly the peptides comprising the amino acid sequence substantially as denoted by SEQ ID: NOs. 1-5 and their biologically functional homologues and derivatives thereof. Also included are polyclonal and monoclonal antibodies directed against them and their compositions for passive immunization against inflammatory and autoimmune diseases and in the treatment of inflammatory and autoimmune diseases. Also encompassed are diagnostic uses of these antibodies, for identifying people at risk of developing arthritis or diabetes, and a method of monitoring progress of the disease conditions and disease prognosis.
    Type: Application
    Filed: December 29, 2008
    Publication date: July 16, 2009
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkei Kashi
  • B-cell epitope peptides of HSP 65, DNA encoding said peptides, antibodies directed against said peptides and the different uses thereof in the treatment of inflammatory and autoimmune diseases
    Patent number: 7488476
    Abstract: B-cell epitope peptides of HSP 65, particularly the peptides comprising the amino acid sequence substantially as denoted by SEQ ID: Nos. 1-5 and their biologically functional homologues and derivatives thereof. Also included are polyclonal and monoclonal antibodies directed against them and their compositions for passive immunization against inflammatory and autoimmune diseases and in the treatment of inflammatory and autoimmune diseases. Also encompassed are diagnostic uses of these antibodies, for identifying people at risk of developing arthritis or diabetes, and a method of monitoring progress of the disease conditions and disease prognosis.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: February 10, 2009
    Assignee: Hadasit Medical Research Services & Development Ltd.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi
  • Use of Liposomal Glucocorticoids for Treating Inflammatory States
    Publication number: 20080003276
    Abstract: The present invention provides the use of a glucocorticoid (GC) or of a GC derivative encapsulated in a liposome for the preparation of a pharmaceutical composition for the treatment of an inflammatory associated condition in a subject, provided that said condition is not associated with a neurodegenerative disease or disorder A specific use concerns a liposomal formulation comprising methylprednisolone sodium hemisuccinate (MPS) for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: September 11, 2005
    Publication date: January 3, 2008
    Inventors: Yechezkel Barenholz, Yaakov Naparstek, Yuval Avnir, Rina Ulmansky
  • Amino acid sequences, DNA encoding the amino acid sequences, antibodies directed against such sequences and the different uses thereof
    Patent number: 7247305
    Abstract: The invention is directed to a peptide comprising the amino acid sequence substantially as denoted by SEQ ID NO:1 and biologically functional homologues and derivatives thereof.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: July 24, 2007
    Assignee: Hadasit Medical Research Services & Development Ltd.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi
  • Novel amino acid sequences, DNA encoding the amino acid sequences, antibodies directed against such sequences and the different uses thereof
    Publication number: 20050123535
    Abstract: B-cell epitope peptides of HSP 65, particularly the peptides comprising the amino acid sequence substantially as denoted by SEQ ID: Nos. 1-5 and their biologically functional homologues and derivatives thereof. Also included are polyclonal and monoclonal antibodies directed against them and their compositions for passive immunization against inflammatory and autoimmune diseases and in the treatment of inflammatory and autoimmune diseases. Also encompassed are diagnostic uses of these antibodies, for identifying people at risk of developing arthritis or diabetes, and a method of monitoring progress of the disease conditions and disease prognosis.
    Type: Application
    Filed: August 31, 2004
    Publication date: June 9, 2005
    Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi
  • Novel amino acid sequences, DNA encoding the amino acid sequences, antibodies directed against such sequences and the different uses thereof
    Publication number: 20050096285
    Abstract: The invention is directed to a peptide comprising the amino acid sequence substantially as denoted by SEQ ID NO:1 and biologically functional homologues and derivatives thereof.
    Type: Application
    Filed: May 24, 2004
    Publication date: May 5, 2005
    Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi
  • B-cell epitope peptides of HSP 65
    Patent number: 6770281
    Abstract: The invention is directed to a peptide, comprising the amino acid sequence substantially as denoted by SEQ ID NO:1 and biologically functional homologues and derivatives thereof.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: August 3, 2004
    Assignee: Hadasit Medical Research Services & Development Ltd.
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi
  • Novel amino acid sequences, DNA encoding the amino acid sequences, antibodies directed against such sequences and the different uses thereof
    Publication number: 20020150586
    Abstract: The invention is directed to a peptide comprising the amino acid sequence substantially as denoted by SEQ ID NO:1 and biologically functional homologues and derivatives thereof.
    Type: Application
    Filed: May 2, 2001
    Publication date: October 17, 2002
    Inventors: Yaakov Naparstek, Rina Ulmansky, Yechezkel Kashi