Patents by Inventor Rina Wu

Rina Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHROMOGENIC IN SITU HYBRIDIZATION METHODS, KITS, AND COMPOSITIONS
    Publication number: 20090233803
    Abstract: The present invention relates to chromogenic (calorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides methods, kits, and compositions for performing bright field cancer diagnostics employing chromogenic in situ hybridization (e.g. to detect gene amplifications, gene translocations, and chromosome polysomy). In preferred embodiments, the present invention provides CISH methods, kits and compositions for detecting HER2 gene status.
    Type: Application
    Filed: August 17, 2007
    Publication date: September 17, 2009
    Applicant: INVITROGEN CORPORATION
    Inventors: Zuo-Rong Shi, Rina Wu
  • CHROMOGENIC IN SITU HYBRIDIZATION METHODS, KITS, AND COMPOSITIONS
    Publication number: 20090137412
    Abstract: The present invention relates to chromogenic (calorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides methods, kits, and compositions for performing bright field cancer diagnostics employing chromogenic in situ hybridization (e.g. to detect gene amplifications, gene translocations, and chromosome polysomy). In preferred embodiments, the present invention provides CISH methods, kits and compositions for detecting HER2 gene status.
    Type: Application
    Filed: August 17, 2007
    Publication date: May 28, 2009
    Applicant: INVITROGEN CORPORATION
    Inventors: Zuo-Rong Shi, Rina Wu
  • Chromogenic in situ hybridization methods, kits, and compositions
    Publication number: 20060035246
    Abstract: The present invention relates to chromogenic (calorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides methods, kits, and compositions for performing bright field cancer diagnostics employing chromogenic in situ hybridization (e.g. to detect gene amplifications, gene translocations, and chromosome polysomy).
    Type: Application
    Filed: April 26, 2005
    Publication date: February 16, 2006
    Inventors: Rina Wu, Abbey Marquez
  • Identifying subjects suitable for topoisomerase II inhibitor treatment
    Patent number: 6942970
    Abstract: The present invention provides methods for diagnosing and treating cancer, and in particular methods for determining the susceptibility of subjects suspected of having breast cancer (or known to have breast cancer) to treatment with topoisomerase II inhibitors. The present invention also provides in situ hybridization probes for specifically detecting topoII? gene sequences.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: September 13, 2005
    Assignee: Zymed Laboratories, Inc.
    Inventors: Jorma Isola, Minna Tanner, Tero Jarvinen, Zuo-Rong Shi, Rina Wu
  • In situ hybridization probes and cancer therapy diagnostics
    Publication number: 20030134279
    Abstract: The present invention provides methods for diagnosing and treating cancer, and in particular methods for determining the susceptibility of subjects suspected of having breast cancer (or known to have breast cancer) to treatment with topoisomerase II inhibitors. The present invention also provides in situ hybridization probes for specifically detecting topoII&agr; gene sequences.
    Type: Application
    Filed: September 14, 2001
    Publication date: July 17, 2003
    Inventors: Jorma Isola, Minna Tanner, Tero Jarvinen, Zuo-Rong Shi, Rina Wu
  • Chromogenic in situ hybridization methods, kits, and compositions
    Publication number: 20030017491
    Abstract: The present invention relates to chromogenic (colorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides methods, kits, and compositions for performing bright field cancer diagnostics employing chromogenic in situ hybridization (e.g. to detect gene amplifications, gene translocations, and chromosome polysomy). In preferred embodiments, the present invention provides CISH methods, kits and compositions for detecting HER2 gene status.
    Type: Application
    Filed: June 17, 2002
    Publication date: January 23, 2003
    Inventors: Zuo-Rong Shi, Rina Wu