Abstract: Non-invasive methods and systems for detection of cancer or arterial vascular disorder involving administering to an individual a composition comprising noble metal nanoparticles that accumulate in a cancerous or injured vascular tissue; optically irradiating an area of a tissue suspected of being a cancerous or injured vascular tissue with a light source outputting an optical signal of at least one wavelength; and measuring diffusion reflection of the area of the irradiated tissue using at least one detector, whereby detection from the measured diffusion reflection of accumulation of the noble metal nanoparticles in this area indicates that the irradiated tissue is a cancerous or injured vascular tissue.

Abstract: Non-invasive methods and systems for detection of cancer or arterial vascular disorder involving administering to an individual a composition comprising noble metal nanoparticles that accumulate in a cancerous or injured vascular tissue; optically irradiating an area of a tissue suspected of being a cancerous or injured vascular tissue with a light source outputting an optical signal of at least one wavelength; and measuring diffusion reflection of the area of the irradiated tissue using at least one detector, whereby detection from the measured diffusion reflection of accumulation of the noble metal nanoparticles in this area indicates that the irradiated tissue is a cancerous or injured vascular tissue.

Abstract: A non-invasive and real-time optical method for detection of cancerous cells that includes the steps of optically irradiating an area of a tissue in which targeted nanoparticles are accumulated with a light source outputting an optical signal of ne or more specific wavelengths; identifying cancerous cells by measuring diffusion reflection of the irradiated tissue where the cancerous cells and the nanoparticles are located; and outputting data indicative of the identified cancerous cells.