Abstract: An ocular lighting assembly (10) including an anchor (16) and a plurality of light guides (14). The anchor is configured to mount to a surface of an eye (30) and to maintain the position of the plurality of discrete light guides. The plurality of light guides are arranged to guide light from a light source into the interior of the eye.

Abstract: A contact electrode assembly for delivering at least one therapeutic agent into ocular tissue of a subject includes a flexible dielectric layer, a first electrode portion, and a second electrode portion. The flexible dielectric includes oppositely disposed first and second surfaces. The first electrode portion is disposed on the first surface of the dielectric layer. The second electrode portion is disposed on a portion of the second surface of the dielectric layer. The second electrode portion includes an interdigitated electrode having a first comb-shaped portion defining a first plurality of fingers and a second comb-shaped portion defining a second plurality of fingers. Each of the first electrode portion, the first comb-shaped portion, and the second comb-shaped portion is electrically connectable to a signal source.

Abstract: An apparatus for delivering at least one therapeutic agent to an ocular tissue of a subject includes at least one electrode, a medicament layer including the at least one therapeutic agent, an electrical signal source, and logic configured to control the electrical signal source. The at least one electrode has oppositely disposed, dome-shaped first and second major surfaces. The first major surface is curved such that the first major surface substantially conforms to a contour of the ocular tissue when placed in contact with the ocular tissue. The medicament layer is disposed on at least a portion of the second major surface. The electrical signal source provides a signal having certain characteristics and is electrically connected to the at least one electrode. The certain characteristics comprise at least one orienting frequency and at least one motivating frequency sufficient to motivate the at least one therapeutic agent into the ocular tissue.

Abstract: A contact electrode assembly for delivering at least one therapeutic agent into ocular tissue of a subject includes a flexible dielectric layer, a first electrode portion, and a second electrode portion. The flexible dielectric includes oppositely disposed first and second surfaces. The first electrode portion is disposed on the first surface of the dielectric layer. The second electrode portion is disposed on a portion of the second surface of the dielectric layer. The second electrode portion includes an interdigitated electrode having a first comb-shaped portion defining a first plurality of fingers and a second comb-shaped portion defining a second plurality of fingers. Each of the first electrode portion, the first comb-shaped portion, and the second comb-shaped portion is electrically connectable to a signal source.

Abstract: An apparatus for delivering at least one therapeutic agent to an ocular tissue of a subject includes at least one electrode, a medicament layer including the at least one therapeutic agent, an electrical signal source, and logic configured to control the electrical signal source. The at least one electrode has oppositely disposed, dome-shaped first and second major surfaces. The first major surface is curved such that the first major surface substantially conforms to the contour of the ocular tissue when placed in contact with the ocular tissue. The medicament layer is disposed on at least a portion of the second major surface. The electrical signal source provides a signal having certain characteristics and is electrically connected to the at least one electrode. The certain characteristics comprise at least one orienting frequency and at least one motivating frequency sufficient to motivate the at least one therapeutic agent into the ocular tissue.

Abstract: A work-strengthenable alloy which includes a gamma prime phase gamma prime particles comprising the following elements in percent by weight:______________________________________ molybdenum 6-16 chromium 13-25 iron 0-23 nickel 10-55 carbon 0-0.05 boron 0-0.05 cobalt balance, at least 20, ______________________________________said alloy also containing one or more elements which form gamma prime phase with nickel,the electron vacancy number, N.sub.v, of the alloy being defined byN.sub.v =0.61 Ni+1.71 Co+2.66 Fe+4.66 Cr+566 Mowherein the respective chemical symbols represent the effective atomic fractions of the respective elements present in the alloy, said value not exceeding the valueN.sub.v =2.82-0.017 W.sub.Fe,where W.sub.Fe is the percent by weight of iron in the alloy for those alloys containing no iron or less than 13 percent by weight iron and W.sub.Fe is 13 for the alloys containing from 13-23 percent by weight iron. The alloys are formed by a melt; and heating the alloy at a temperature of from 600.

Abstract: This invention relates to a nickel-cobalt alloy comprising the following elements in percent by weight:______________________________________ Carbon about 0-0.05 Molybdenum about 6-11 Iron about 0-1 Titanium about 0-6 Chromium about 15-23 Boron about 0.005-0.020 Columbium about 1.1-10 Aluminum about 0.4-4.0 Cobalt about 30-60 Nickel balance ______________________________________the alloy having an electron vacancy number, N.sub.v, defined by N.sub.v =0.61 Ni+1.71 Co+2.66 Fe+4.66 Cr+5.66 Mo wherein the respective chemical symbols represent the effective atomic fractions of the respective elements present in the alloy, the value not exceeding the value N.sub.v =2.82-0.017 W.sub.Fe, wherein W.sub.Fe is the percent by weight of iron in the alloy.In one aspect, the alloy of the present invention is preferably finally cold worked at ambient temperature to a reduction in cross-section of at least 5% and up to about 40%, although higher levels of cold work may be used with some loss of thermomechanical properties.

Abstract: A method of making a work-strengthenable alloy which includes a gamma prime phase which method comprises forming a melt comprising the following elements in percent by weight:______________________________________ molybdenum 6-16 chromium 13-25 iron 0-23 nickel 10-55 carbon 0-0.05 boron 0-0.05 cobalt balance, at least 20, ______________________________________said alloy also containing one or more elements which form gamma prime phase with nickel, the electron vacancy number, N.sub.v, of the alloy being defined byN.sub.v =0.61 Ni+1.71 Co+2.66 Fe+4.66 Cr+5.66 Mowherein the respective chemical symbols represent the effective atomic fractions of the respective elements present in the alloy, said value not exceeding the valueN.sub.v =2.82-0.017 W.sub.Fe,where W.sub.Fe is the percent by weight of iron in the alloy for those alloys containing no iron or less than 13 percent by weight iron and W.sub.