Abstract: According to an example aspect of the present invention, there is provided generating, Low-Field-Magnetic Resonance Imaging, LF-MRI, or Ultra-Low-Field Magnetic Resonance Imaging, ULF-MRI, data with respect to an image frame, determining a sensorwise agreement of the data with determined sensitivity profiles, and determining a mapping between the image frame and a sensor frame, such that the sensorwise agreement has been fulfilled.

Abstract: According to an example aspect of the present invention, there is provided generating, Low-Field-Magnetic Resonance Imaging, LF-MRI, or Ultra-Low-Field Magnetic Resonance Imaging, ULF-MRI, data with respect to an image frame, determining a sensorwise agreement of the data with determined sensitivity profiles, and determining a mapping between the image frame and a sensor frame, such that the sensorwise agreement has been fulfilled.

Abstract: The invention relates to a transcranial magnetic stimulation device comprising: at least two coils, an input channel for each coil, a control unit, and at least one energy storage for storing energy for the at least two coils, the control unit being configured to: determine at least one stimulus intensity; determine an energy level stored in the at least one energy storage; determine a modulation pattern for each coil; and generate at least one control signal for controlling the input channel of the at least one coil of the at least two coils according to the determined modulation pattern in order to control an input of each coil from the at least one energy storage. A method is also disclosed.

Abstract: Provided herein is a multichannel Transcranial Magnetic Stimulation (mTMS) coil device with two or more overlapping coil windings within a casing. The mTMS coil device is capable of adjusting parameters of the stimulation of magnetic and induced electric fields through the selective control of the multiple coil windings within the mTMS coil device. Additionally, provided are methods of operation including navigated TMS for adjusting parameters such as location, direction and/or orientation of magnetic and induced electric fields from mTMS coil devices.

Abstract: The invention relates to a transcranial magnetic stimulation device comprising: at least two coils (130, 140), an input channel (150, 160) for each coil (130, 40), a control unit (170), at least one energy storage (120) for storing energy for the at least two coils (130, 140), the control unit (170) is configured to: determine at least one stimulus intensity; determine an energy level stored in the at least one energy storage (120); determine a modulation pattern for each coil (130, 140); generate at least one control signal for controlling the input channel of the at least one coil (130, 140) of the at least two coils (130, 140) according to the determined modulation pattern in order to control an input of each coil (130, 140) from the at least one energy storage (120). A method is also disclosed.

Abstract: The invention relates to a prepolarizing magnetic resonance- or relaxation-based measurement system, comprising a prepolarizing coil for producing a prepolarizing field at the target zone, means for pulsing the prepolarizing field according to a first pulsing scheme, and means for measuring magnetization of a target placed in the target zone. According to the invention, the system further comprises a shielding coil for producing a shielding field and means for pulsing the shielding field according to a second pulsing scheme, whereby the shielding coil and the second pulsing scheme are arranged to reduce the formation of unwanted transient fields caused by the coupling of the prepolarizing coil to conducting or magnetic structures in the surroundings of the system. The invention also relates to a corresponding method of measurement and a process of designing the pulsing schemes for the system or process.

Abstract: Provided herein is a multichannel Transcranial Magnetic Stimulation (mTMS) coil device with two or more overlapping coil windings within a casing. The mTMS coil device is capable of adjusting parameters of the stimulation of magnetic and induced electric fields through the selective control of the multiple coil windings within the mTMS coil device. Additionally, provided are methods of operation including navigated TMS for adjusting parameters such as location, direction and/or orientation of magnetic and induced electric fields from mTMS coil devices.

Abstract: The invention relates to a prepolarizing magnetic resonance- or relaxation-based measurement system, comprising a prepolarizing coil for producing a prepolarizing field at the target zone, means for pulsing the prepolarizing field according to a first pulsing scheme, and means for measuring magnetization of a target placed in the target zone. According to the invention, the system further comprises a shielding coil for producing a shielding field and means for pulsing the shielding field according to a second pulsing scheme, whereby the shielding coil and the second pulsing scheme are arranged to reduce the formation of unwanted transient fields caused by the coupling of the prepolarizing coil to conducting or magnetic structures in the surroundings of the system. The invention also relates to a corresponding method of measurement and a process of designing the pulsing schemes for the system or process.

Abstract: An error in the co-registration of a coordinate system used to represent a head of a subject in image data with a coordinate system used to represent the location of trackers affixed to the scalp surface of the head and a tracked device, such as a transcranial magnetic stimulation (“TMS”) induction coil device, is corrected using information representative of the actual distance between the tracked device and the scalp of the subject, such that representations of the tracked device and the subject's head are accurately shown on a display of a navigated brain stimulation (“NBS”) system tracking movement of the tracked device in relation to the subject's head. The correction of the error in the co-registration is performed without collecting additional tracking information from trackers on a tracked TMS coil device and the head, which avoids interrupting NBS using the TMS coil device.

Abstract: An error in the co-registration of a coordinate system used to represent a head of a subject in image data with a coordinate system used to represent the location of trackers affixed to the scalp surface of the head and a tracked device, such as a transcranial magnetic stimulation (“TMS”) induction coil device, is corrected using information representative of the actual distance between the tracked device and the scalp of the subject, such that representations of the tracked device and the subject's head are accurately shown on a display of a navigated brain stimulation (“NBS”) system tracking movement of the tracked device in relation to the subject's head. The correction of the error in the co-registration is performed without collecting additional tracking information from trackers on a tracked TMS coil device and the head, which avoids interrupting NBS using the TMS coil device.

Abstract: Disclosed is a method for producing a magnetic stimulation effect and/or a fake magnetic stimulation effect in a biological tissue. According to the method, the real magnetic stimulation is effected by virtue of inducing an electromagnetic field in said biological tissue with a sufficiently strong field strength to essentially excite said tissue, and the fake magnetic stimulation is effected by virtue of inducing an electromagnetic field in said biological tissue with a field strength that is weaker than the electromagnetic field required for an essential excitation of said tissue.

Abstract: The present invention relates to a stimulator head of a magnetic stimulator used in the stimulation of living tissue such as the human brain. Such a stimulator bead comprises a stimulator head body (3) suited for mounting the stimulator head on the magnetic stimulator equipment, at least one coil (1) which is connected to said stimulator head body (3) and is designed suitable for generating a stimulating magnetic field, and conductors (7) for passing electric current from said magnetic stimulator into any of said at least one coil (1). According to the invention, the stimulator head includes a housing (2) which is connected to said stimulator head body (3) and is designed to enclose at least one air-tight space (5) which further separates each of said at least one stimulator coil (1) from the other parts of said housing (2) facing the object being stimulated.

Abstract: The invention relates to a method and apparatus for examining and mapping the reactivity of and connections between different cortical areas. In the method an electromagnetic stimulus is induced in the interior parts of the head and the electromagnetic field generated around the skull is measured by electrical means (1). According to the method, the electromagnetic activity of the brain is measured using multichannel equipment, artefacts caused by the stimulus are eliminated from the signal containing the electromagnetic activity, a visualization of the activity changes in the measured signals is formed, and the areas of the head related to said activity generating said electromagnetic field are localized, or alternatively, the maximum of the sensitivity pattern of the multichannel activity measurement system is focused to a desired point.

Abstract: The present invention is related to a method and an apparatus for separating the different components of evoked responses and spontaneous activity of the brain, as well as signals measured from the heart, from each other. The apparatus according to the invention presents the measured signals in graphic form and the user selects from the signals such a time instant, time interval or frequency band, which plausibly can be related to a given source component. The apparatus forms a signal vector from the temporal or frequency signals thus selected, projects the unprocessed signal onto the signal vector thus formed, and subtracts the projection from the unprocessed signals, whereby the projected vector and the set of signals remaining after the subtraction step provide the separation of the unprocessed signals into the selected component and such a part which is clean of contribution of the selected component.

Abstract: A method and apparatus for finding the location of electrodes attached to a body, particularly to the head is provided with at least one first coil arranged in conjunction with each electrode. The coils of the electrodes form a coil group to be localized. A plurality of other coils are arranged in the vicinity of the electrodes so that the position of the coils is uniquely known. The second set of coils forms a fixed coil group. A magnetic field is induced in at least a part of either the first coil group or the second coil group. The set of coils not generating the magnetic field are used for detecting the induced magnetic field. The measured results from the group of coils acting as a magnetometer are used to determine the position of electrodes. Using this implementation, the positions of the electrodes can be determined in a quick and accurate manner.