Patents by Inventor Rita L. Strack

Rita L. Strack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA sequences that induce fluorescence of small molecule fluorophores
    Patent number: 9664676
    Abstract: The present invention relates to novel nucleic acid molecules, called aptamers, that bind specifically to a small molecule fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: May 30, 2017
    Assignee: Cornell University
    Inventors: Samie R. Jaffrey, Rita L. Strack, Grigory Filonov, Wenjiao Song
  • RNA SEQUENCES THAT INDUCE FLUORESCENCE OF SMALL MOLECULE FLUOROPHORES
    Publication number: 20150141282
    Abstract: The present invention relates to novel nucleic acid molecules, called aptamers, that bind specifically to a small molecule fluorophore and thereby enhance the fluorescence signal of the fluorophore upon exposure to radiation of suitable wavelength. Molecular complexes formed between the novel fluorophores, novel nucleic acid molecules, and their target molecules are described, and the use of multivalent aptamer constructs as fluorescent sensors for target molecules of interest are also described.
    Type: Application
    Filed: September 8, 2014
    Publication date: May 21, 2015
    Inventors: Samie R. Jaffrey, Rita L. Strack, Grigory Filonov, Wenjiao Song
  • Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation
    Patent number: 8679749
    Abstract: Polynucleotides encoding variant polypeptides of DsRed are provided herein. The DsRed variants have increased bacterial expression, reduced aggregation, increased solubility, shifted emission spectra or increased brightness relative to a wild-type DsRed.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: March 25, 2014
    Assignee: The University of Chicago
    Inventors: Benjamin S. Glick, Daniel E. Strongin, Robert Keenan, Rita L. Strack, Dibyendu Bhattacharyya
  • RED FLUORESCENT PROTEINS WITH ENHANCED BACTERIAL EXPRESSION, INCREASED BRIGHTNESS AND REDUCED AGGREGATION
    Publication number: 20110020784
    Abstract: Polynucleotides encoding variant polypeptides of DsRed are provided herein. The DsRed variants have increased bacterial expression, reduced aggregation, increased solubility, shifted emission spectra or increased brightness relative to a wild-type DsRed.
    Type: Application
    Filed: November 3, 2008
    Publication date: January 27, 2011
    Inventors: Benjamin S. Glick, Daniel E. Strongin, Robert Keenan, Rita L. Strack, Dibyendu Bhattacharyya